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OPENSEQ.org

SLMA - Nucleoid occlusion factor SlmA
UniProt: P0C093 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11191
Length: 198 (192)
Sequences: 20477
Seq/Len: 106.65

SLMA
Paralog alert: 0.84 [within 20: 0.25] - ratio of genomes with paralogs
Cluster includes: ACRR BDCR BETI COMR ENVR NEMR RUTR SLMA UIDR YBIH YBJK YJDC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
26_S 36_K 3.946 1.00
21_L 40_S 3.664 1.00
35_A 45_E 3.41 1.00
53_P 57_R 2.901 1.00
137_R 156_T 2.31 1.00
22_M 32_I 2.261 1.00
23_L 32_I 2.215 1.00
13_E 65_F 2.201 1.00
87_R 142_E 2.195 1.00
83_D 86_A 2.165 1.00
54_S 57_R 2.162 1.00
25_S 40_S 2.158 1.00
11_R 14_E 2.046 1.00
18_S 40_S 2.028 1.00
12_R 61_S 1.999 1.00
44_S 47_A 1.952 1.00
38_A 48_L 1.947 1.00
141_R 145_M 1.926 1.00
35_A 39_A 1.884 1.00
137_R 141_R 1.855 1.00
13_E 17_Q 1.851 1.00
19_L 23_L 1.833 1.00
22_M 40_S 1.817 1.00
14_E 18_S 1.809 1.00
22_M 36_K 1.747 1.00
141_R 155_E 1.735 1.00
20_A 65_F 1.715 1.00
64_E 124_R 1.713 1.00
61_S 64_E 1.681 1.00
22_M 26_S 1.642 1.00
75_N 135_Q 1.606 1.00
16_L 61_S 1.548 1.00
141_R 144_R 1.547 1.00
17_Q 65_F 1.532 1.00
23_L 28_G 1.502 1.00
18_S 21_L 1.499 1.00
19_L 58_M 1.494 1.00
143_K 149_E 1.488 1.00
32_I 37_L 1.471 1.00
89_R 187_D 1.471 1.00
34_T 48_L 1.463 1.00
57_R 61_S 1.451 1.00
83_D 148_G 1.438 1.00
34_T 49_Y 1.437 1.00
56_T 118_Q 1.425 1.00
12_R 51_H 1.424 1.00
65_F 69_S 1.397 0.99
27_D 31_R 1.389 0.99
36_K 39_A 1.377 0.99
27_D 32_I 1.376 0.99
21_L 25_S 1.368 0.99
133_E 160_S 1.361 0.99
52_F 61_S 1.352 0.99
143_K 148_G 1.314 0.99
34_T 45_E 1.309 0.99
142_E 146_R 1.298 0.99
37_L 58_M 1.294 0.99
33_T 36_K 1.291 0.99
36_K 40_S 1.284 0.99
28_G 59_F 1.281 0.99
89_R 93_L 1.268 0.99
164_A 168_G 1.255 0.99
60_D 124_R 1.248 0.99
20_A 62_L 1.244 0.98
43_V 47_A 1.231 0.98
93_L 186_F 1.221 0.98
16_L 52_F 1.216 0.98
18_S 41_V 1.205 0.98
161_Q 165_F 1.203 0.98
47_A 50_R 1.202 0.98
137_R 155_E 1.195 0.98
154_D 157_L 1.188 0.98
16_L 62_L 1.185 0.98
85_T 89_R 1.182 0.98
26_S 31_R 1.173 0.98
157_L 188_A 1.168 0.97
10_N 13_E 1.167 0.97
20_A 66_I 1.166 0.97
60_D 64_E 1.163 0.97
84_T 146_R 1.161 0.97
144_R 155_E 1.159 0.97
87_R 139_V 1.154 0.97
93_L 187_D 1.152 0.97
44_S 50_R 1.143 0.97
86_A 90_L 1.139 0.97
17_Q 21_L 1.125 0.97
20_A 24_E 1.1 0.96
181_R 184_D 1.098 0.96
64_E 68_D 1.09 0.96
49_Y 54_S 1.077 0.95
10_N 14_E 1.071 0.95
140_L 155_E 1.061 0.95
56_T 120_R 1.057 0.95
90_L 93_L 1.055 0.95
93_L 183_T 1.051 0.94
11_R 51_H 1.05 0.94
192_L 196_Q 1.043 0.94
18_S 22_M 1.04 0.94
56_T 60_D 1.034 0.94
57_R 60_D 1.026 0.94
5_Q 8_K 1.023 0.93
135_Q 138_Q 1.023 0.93
86_A 89_R 1.011 0.93
73_R 94_L 1.009 0.93
133_E 137_R 1.005 0.93
46_A 50_R 1.001 0.92
139_V 143_K 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4gckA40.99491000.08Contact Map0.756
2ibdA20.98991000.094Contact Map0.751
4gfkA20.98481000.1Contact Map0.732
2xdnA40.99491000.1Contact Map0.736
3vibA40.99491000.113Contact Map0.747
3kz9A40.98991000.118Contact Map0.798
2gfnA20.98991000.119Contact Map0.778
3g1oA10.98481000.119Contact Map0.654
3dcfA20.97471000.119Contact Map0.614
1vi0A20.97981000.12Contact Map0.782

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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