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YBJK - Uncharacterized HTH-type transcriptional regulator YbjK
UniProt: P75811 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13680
Length: 178 (172)
Sequences: 14523
Seq/Len: 84.44
YBJK
Paralog alert: 0.76 [within 20: 0.18] - ratio of genomes with paralogs
Cluster includes: ACRR BDCR BETI COMR ENVR NEMR RUTR SLMA UIDR YBIH YBJK YJDC
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
24_Y 33_K 4.337 1.00
19_E 37_L 3.736 1.00
32_R 42_L 3.689 1.00
50_S 54_E 3.025 1.00
23_L 37_L 2.73 1.00
9_R 12_K 2.437 1.00
11_E 62_S 2.431 1.00
20_A 29_V 2.223 1.00
41_P 44_S 2.165 1.00
21_V 29_V 2.145 1.00
80_D 83_G 2.107 1.00
58_E 61_S 2.049 1.00
51_G 54_E 2.019 1.00
35_A 45_M 2.012 1.00
16_A 37_L 1.997 1.00
10_R 58_E 1.985 1.00
17_T 21_V 1.924 1.00
15_Q 62_S 1.838 1.00
11_E 15_Q 1.829 1.00
12_K 16_A 1.828 1.00
90_D 170_L 1.783 1.00
21_V 26_I 1.725 1.00
17_T 55_L 1.724 1.00
61_S 122_V 1.72 1.00
165_S 168_E 1.706 1.00
53_D 116_K 1.703 1.00
32_R 36_T 1.683 1.00
20_A 24_Y 1.668 1.00
29_V 34_I 1.61 1.00
20_A 37_L 1.603 1.00
31_H 46_T 1.599 1.00
25_G 28_A 1.587 1.00
54_E 58_E 1.574 1.00
18_L 62_S 1.573 1.00
20_A 33_K 1.565 1.00
84_A 136_Q 1.547 1.00
31_H 45_M 1.534 1.00
145_A 149_F 1.513 1.00
34_I 55_L 1.492 1.00
19_E 23_L 1.483 1.00
14_I 58_E 1.479 1.00
131_Q 141_G 1.472 1.00
25_G 29_V 1.463 1.00
62_S 66_I 1.463 1.00
148_A 152_G 1.462 1.00
10_R 48_Y 1.45 1.00
26_I 56_L 1.424 1.00
16_A 19_E 1.388 0.99
135_E 140_P 1.38 0.99
49_F 58_E 1.361 0.99
18_L 59_A 1.357 0.99
33_K 37_L 1.338 0.99
33_K 36_T 1.298 0.99
86_Q 174_E 1.279 0.99
40_V 44_S 1.272 0.99
9_R 48_Y 1.263 0.99
31_H 42_L 1.261 0.99
16_A 38_A 1.254 0.99
30_T 33_K 1.25 0.99
131_Q 135_E 1.249 0.99
14_I 49_F 1.249 0.99
8_Q 11_E 1.235 0.98
15_Q 19_E 1.231 0.98
44_S 48_Y 1.225 0.98
61_S 65_E 1.222 0.98
57_L 61_S 1.218 0.98
46_T 51_G 1.189 0.98
16_A 20_A 1.176 0.98
83_G 87_A 1.172 0.98
14_I 59_A 1.157 0.97
54_E 57_L 1.151 0.97
44_S 47_Y 1.143 0.97
128_Q 132_Q 1.136 0.97
82_P 86_Q 1.133 0.97
53_D 57_L 1.123 0.97
86_Q 90_D 1.117 0.96
24_Y 29_V 1.116 0.96
53_D 118_L 1.11 0.96
108_Q 111_A 1.104 0.96
13_I 38_A 1.099 0.96
18_L 22_K 1.097 0.96
57_L 122_V 1.084 0.96
19_E 101_D 1.063 0.95
69_R 73_A 1.058 0.95
24_Y 28_A 1.055 0.95
43_G 47_Y 1.053 0.95
72_Q 129_R 1.025 0.93
17_T 59_A 1.024 0.93
8_Q 12_K 1.023 0.93
121_T 125_N 1.018 0.93
13_I 48_Y 1.011 0.93
58_E 62_S 1.009 0.93
26_I 52_I 1.007 0.93
108_Q 112_L 1.003 0.93
13_I 45_M 1.003 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2dg8A4199.90.147Contact Map0.771
3htaA4199.90.164Contact Map0.762
2gfnA2199.90.177Contact Map0.773
2np5A40.994499.90.181Contact Map0.746
2nx4A40.994499.90.189Contact Map0.777
3he0A3199.90.201Contact Map0.781
3colA2199.90.204Contact Map0.753
3crjA40.988899.90.207Contact Map0.814
3pasA40.994499.90.21Contact Map0.783
4gfkA20.994499.90.212Contact Map0.712
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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