| UniProt: | P0ACT2 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11741 | ||
| Length: | 220 (200) | ||
| Sequences: | 15587 | ||
| Seq/Len: | 77.94 |
| ENVR
Paralog alert: 0.81 [within 20: 0.20] - ratio of genomes with paralogs Cluster includes: ACRR BDCR BETI COMR ENVR NEMR RUTR SLMA UIDR YBIH YBJK YJDC |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 27_H | 36_D | 3.999 | 1.00 | |
| 22_A | 40_A | 3.813 | 1.00 | |
| 35_N | 45_R | 3.456 | 1.00 | |
| 53_E | 57_Q | 2.871 | 1.00 | |
| 23_Q | 32_T | 2.534 | 1.00 | |
| 88_Q | 146_A | 2.487 | 1.00 | |
| 26_Q | 40_A | 2.445 | 1.00 | |
| 14_Q | 65_Q | 2.327 | 1.00 | |
| 141_R | 160_D | 2.27 | 1.00 | |
| 24_F | 32_T | 2.229 | 1.00 | |
| 84_D | 87_Q | 2.213 | 1.00 | |
| 54_N | 57_Q | 2.159 | 1.00 | |
| 145_Q | 149_Q | 2.085 | 1.00 | |
| 44_T | 47_A | 2.068 | 1.00 | |
| 38_A | 48_I | 2.035 | 1.00 | |
| 61_E | 64_L | 2.001 | 1.00 | |
| 12_T | 15_E | 1.968 | 1.00 | |
| 20_A | 24_F | 1.943 | 1.00 | |
| 23_Q | 40_A | 1.928 | 1.00 | |
| 14_Q | 18_E | 1.924 | 1.00 | |
| 13_R | 61_E | 1.923 | 1.00 | |
| 141_R | 145_Q | 1.922 | 1.00 | |
| 35_N | 39_D | 1.913 | 1.00 | |
| 19_T | 40_A | 1.856 | 1.00 | |
| 145_Q | 159_L | 1.81 | 1.00 | |
| 23_Q | 36_D | 1.795 | 1.00 | |
| 15_E | 19_T | 1.794 | 1.00 | |
| 90_R | 191_P | 1.791 | 1.00 | |
| 145_Q | 148_Q | 1.742 | 1.00 | |
| 196_N | 200_M | 1.706 | 1.00 | |
| 147_C | 153_V | 1.691 | 1.00 | |
| 21_I | 65_Q | 1.667 | 1.00 | |
| 32_T | 37_I | 1.662 | 1.00 | |
| 75_E | 139_T | 1.653 | 1.00 | |
| 84_D | 152_C | 1.615 | 1.00 | |
| 94_I | 191_P | 1.605 | 1.00 | |
| 23_Q | 27_H | 1.597 | 1.00 | |
| 34_L | 48_I | 1.551 | 1.00 | |
| 24_F | 29_V | 1.536 | 1.00 | |
| 34_L | 49_Y | 1.533 | 1.00 | |
| 18_E | 65_Q | 1.524 | 1.00 | |
| 64_L | 129_I | 1.523 | 1.00 | |
| 13_R | 51_H | 1.521 | 1.00 | |
| 17_I | 61_E | 1.482 | 1.00 | |
| 147_C | 152_C | 1.457 | 1.00 | |
| 34_L | 45_R | 1.447 | 1.00 | |
| 161_V | 192_A | 1.438 | 1.00 | |
| 28_G | 31_K | 1.428 | 1.00 | |
| 28_G | 32_T | 1.409 | 1.00 | |
| 52_F | 61_E | 1.377 | 0.99 | |
| 57_Q | 61_E | 1.375 | 0.99 | |
| 85_P | 150_Q | 1.36 | 0.99 | |
| 86_F | 90_R | 1.356 | 0.99 | |
| 22_A | 26_Q | 1.353 | 0.99 | |
| 37_I | 58_L | 1.352 | 0.99 | |
| 168_G | 172_G | 1.352 | 0.99 | |
| 60_N | 129_I | 1.348 | 0.99 | |
| 17_I | 62_M | 1.34 | 0.99 | |
| 36_D | 39_D | 1.338 | 0.99 | |
| 36_D | 40_A | 1.329 | 0.99 | |
| 33_T | 36_D | 1.327 | 0.99 | |
| 19_T | 22_A | 1.323 | 0.99 | |
| 146_A | 150_Q | 1.319 | 0.99 | |
| 185_D | 188_K | 1.305 | 0.99 | |
| 65_Q | 69_L | 1.303 | 0.99 | |
| 56_T | 123_M | 1.269 | 0.99 | |
| 43_V | 47_A | 1.256 | 0.99 | |
| 199_R | 202_M | 1.235 | 0.98 | |
| 148_Q | 159_L | 1.215 | 0.98 | |
| 165_I | 169_A | 1.201 | 0.98 | |
| 90_R | 195_D | 1.197 | 0.98 | |
| 144_L | 159_L | 1.195 | 0.98 | |
| 90_R | 94_I | 1.189 | 0.98 | |
| 12_T | 51_H | 1.185 | 0.98 | |
| 141_R | 159_L | 1.184 | 0.98 | |
| 44_T | 50_W | 1.183 | 0.98 | |
| 195_D | 199_R | 1.181 | 0.98 | |
| 11_K | 15_E | 1.174 | 0.98 | |
| 19_T | 41_A | 1.17 | 0.97 | |
| 29_V | 59_F | 1.169 | 0.97 | |
| 20_A | 58_L | 1.165 | 0.97 | |
| 86_F | 202_M | 1.155 | 0.97 | |
| 87_Q | 91_E | 1.15 | 0.97 | |
| 6_K | 9_A | 1.148 | 0.97 | |
| 158_D | 161_V | 1.136 | 0.97 | |
| 27_H | 31_K | 1.13 | 0.97 | |
| 17_I | 52_F | 1.12 | 0.96 | |
| 88_Q | 143_V | 1.117 | 0.96 | |
| 128_V | 132_K | 1.105 | 0.96 | |
| 21_I | 62_M | 1.103 | 0.96 | |
| 94_I | 187_Y | 1.101 | 0.96 | |
| 18_E | 22_A | 1.091 | 0.96 | |
| 60_N | 64_L | 1.08 | 0.95 | |
| 143_V | 147_C | 1.075 | 0.95 | |
| 21_I | 66_Q | 1.072 | 0.95 | |
| 64_L | 68_S | 1.063 | 0.95 | |
| 47_A | 50_W | 1.053 | 0.95 | |
| 135_F | 138_Q | 1.05 | 0.94 | |
| 49_Y | 54_N | 1.046 | 0.94 | |
| 61_E | 65_Q | 1.034 | 0.94 | |
| 159_L | 163_M | 1.027 | 0.94 | |
| 146_A | 149_Q | 1.017 | 0.93 | |
| 91_E | 94_I | 1.015 | 0.93 | |
| 57_Q | 60_N | 1.013 | 0.93 | |
| 148_Q | 155_N | 1.013 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2xdnA | 4 | 0.95 | 100 | 0.165 | Contact Map | 0.735 |
| 3lhqA | 2 | 0.9818 | 100 | 0.209 | Contact Map | 0.748 |
| 2w53A | 2 | 0.9864 | 100 | 0.209 | Contact Map | 0.803 |
| 3vibA | 4 | 0.95 | 100 | 0.222 | Contact Map | 0.749 |
| 2wuiA | 1 | 0.9455 | 100 | 0.223 | Contact Map | 0.627 |
| 1vi0A | 2 | 0.9318 | 100 | 0.242 | Contact Map | 0.791 |
| 2gfnA | 2 | 0.9273 | 100 | 0.255 | Contact Map | 0.772 |
| 2ibdA | 2 | 0.9091 | 100 | 0.256 | Contact Map | 0.747 |
| 3s5rA | 2 | 0.95 | 100 | 0.263 | Contact Map | 0.667 |
| 4gckA | 4 | 0.8909 | 100 | 0.264 | Contact Map | 0.721 |
Sequence Conservation (Image Generated using WebLogo v3)