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YEJB - Inner membrane ABC transporter permease protein YejB
UniProt: P0AFU0 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12038
Length: 364 (325)
Sequences: 6261
Seq/Len: 19.26
YEJB
Paralog alert: 0.79 [within 20: 0.10] - ratio of genomes with paralogs
Cluster includes: DDPB DDPC DPPB DPPC GSIC GSID NIKB NIKC OPPB OPPC SAPB SAPC YEJB YEJE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
91_H 96_D 3.869 1.00
97_K 101_E 3.789 1.00
28_Q 102_R 3.644 1.00
97_K 105_K 3.507 1.00
20_I 103_Y 3.485 1.00
33_G 90_T 3.353 1.00
108_W 112_R 3.345 1.00
83_P 87_A 3.254 1.00
104_F 108_W 3.024 1.00
264_R 270_E 2.995 1.00
21_T 103_Y 2.841 1.00
135_V 311_L 2.755 1.00
251_F 278_V 2.708 1.00
260_V 278_V 2.689 1.00
272_N 276_K 2.648 1.00
287_I 355_V 2.631 1.00
100_H 104_F 2.586 1.00
142_W 232_V 2.522 1.00
202_F 229_T 2.362 1.00
128_L 317_L 2.258 1.00
146_I 236_V 2.187 1.00
19_I 338_T 2.177 1.00
291_P 348_S 2.163 1.00
262_T 266_K 2.15 1.00
202_F 226_W 2.143 1.00
316_L 320_E 2.137 1.00
288_A 352_Y 2.11 1.00
255_V 278_V 1.941 1.00
109_D 114_D 1.926 1.00
20_I 106_M 1.91 1.00
87_A 91_H 1.872 1.00
124_S 127_T 1.87 1.00
88_E 92_R 1.864 1.00
110_Y 115_F 1.857 1.00
3_A 7_R 1.856 1.00
165_R 169_W 1.845 1.00
161_Y 164_S 1.828 1.00
86_I 90_T 1.806 1.00
101_E 105_K 1.803 1.00
149_L 153_P 1.778 1.00
254_E 259_Y 1.778 1.00
85_V 88_E 1.764 1.00
351_S 354_L 1.746 1.00
17_W 21_T 1.744 1.00
121_R 128_L 1.732 1.00
16_L 339_L 1.732 1.00
123_A 127_T 1.718 1.00
269_S 272_N 1.707 1.00
189_L 234_A 1.688 1.00
10_L 14_P 1.676 1.00
154_L 170_S 1.662 1.00
150_V 153_P 1.638 1.00
194_A 204_L 1.629 1.00
160_V 274_L 1.628 1.00
126_L 130_K 1.622 1.00
125_V 332_G 1.61 1.00
12_V 342_L 1.595 1.00
159_A 252_L 1.592 1.00
321_A 329_V 1.587 1.00
82_D 85_V 1.586 1.00
259_Y 281_N 1.573 1.00
254_E 260_V 1.566 1.00
101_E 104_F 1.563 1.00
123_A 131_D 1.557 1.00
254_E 257_K 1.556 1.00
202_F 230_L 1.551 1.00
236_V 240_F 1.533 1.00
87_A 90_T 1.532 1.00
184_L 188_L 1.532 1.00
191_V 196_G 1.519 1.00
266_K 277_H 1.515 1.00
271_K 275_W 1.496 1.00
192_F 196_G 1.495 1.00
17_W 107_L 1.492 1.00
105_K 108_W 1.483 1.00
258_Q 261_V 1.483 1.00
94_G 97_K 1.472 1.00
17_W 103_Y 1.471 1.00
157_R 161_Y 1.465 1.00
163_G 167_D 1.462 1.00
32_G 325_R 1.458 1.00
167_D 248_K 1.457 1.00
254_E 282_A 1.454 1.00
177_G 241_A 1.446 1.00
166_F 170_S 1.43 1.00
98_P 101_E 1.429 1.00
35_V 86_I 1.425 1.00
192_F 199_F 1.411 1.00
284_L 352_Y 1.394 0.99
16_L 342_L 1.39 0.99
128_L 329_V 1.388 0.99
317_L 329_V 1.382 0.99
185_F 237_I 1.364 0.99
155_G 247_T 1.363 0.99
135_V 138_T 1.363 0.99
115_F 332_G 1.36 0.99
188_L 192_F 1.357 0.99
12_V 346_I 1.349 0.99
318_G 333_T 1.341 0.99
260_V 273_I 1.337 0.99
21_T 99_I 1.337 0.99
94_G 105_K 1.334 0.99
150_V 240_F 1.326 0.99
148_Y 290_F 1.318 0.99
232_V 236_V 1.317 0.99
157_R 166_F 1.313 0.99
189_L 230_L 1.311 0.99
180_I 185_F 1.295 0.99
6_I 10_L 1.289 0.99
347_V 351_S 1.28 0.99
105_K 109_D 1.27 0.99
147_I 239_G 1.268 0.99
156_I 251_F 1.262 0.99
170_S 244_T 1.261 0.99
193_F 199_F 1.258 0.99
350_I 354_L 1.248 0.99
333_T 337_F 1.243 0.98
89_I 93_Y 1.242 0.98
161_Y 166_F 1.24 0.98
146_I 232_V 1.236 0.98
28_Q 99_I 1.232 0.98
21_T 25_F 1.226 0.98
20_I 335_Y 1.221 0.98
151_S 243_L 1.22 0.98
186_A 234_A 1.196 0.98
159_A 251_F 1.188 0.98
182_A 305_I 1.183 0.98
225_L 229_T 1.183 0.98
141_L 145_L 1.182 0.98
163_G 168_V 1.18 0.98
103_Y 107_L 1.165 0.97
25_F 99_I 1.157 0.97
302_S 305_I 1.156 0.97
127_T 130_K 1.143 0.97
4_Y 8_R 1.132 0.97
144_T 290_F 1.122 0.97
5_L 350_I 1.117 0.96
131_D 134_P 1.114 0.96
118_S 326_D 1.107 0.96
151_S 247_T 1.105 0.96
155_G 159_A 1.096 0.96
229_T 233_L 1.095 0.96
247_T 286_V 1.091 0.96
344_L 348_S 1.085 0.96
97_K 100_H 1.085 0.96
138_T 228_I 1.072 0.95
159_A 255_V 1.063 0.95
115_F 126_L 1.057 0.95
91_H 97_K 1.056 0.95
123_A 128_L 1.05 0.94
268_V 273_I 1.043 0.94
89_I 92_R 1.038 0.94
193_F 201_L 1.038 0.94
270_E 273_I 1.035 0.94
110_Y 335_Y 1.033 0.94
186_A 308_M 1.033 0.94
4_Y 361_F 1.03 0.94
9_L 346_I 1.026 0.94
169_W 173_F 1.014 0.93
295_I 341_G 1.014 0.93
246_L 289_G 1.013 0.93
129_I 333_T 1.008 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3tuiA40.576999.90.782Contact Map0.725
3rlfF10.802299.80.797Contact Map0.514
2onkC40.72899.80.803Contact Map0.577
3d31C20.733599.70.817Contact Map0.548
3rlfG10.774799.60.84Contact Map0.381
3s82A20.2473390.966Contact Map0.218
2p02A10.2363320.967Contact Map0.217
1p7lA40.252726.90.968Contact Map0.297
3imlA40.27224.60.969Contact Map0.207
3so4A40.2511.30.973Contact Map0.21
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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