| UniProt: | P0AEF8 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12625 | ||
| Length: | 339 (321) | ||
| Sequences: | 6402 | ||
| Seq/Len: | 19.94 |
| DPPB
Paralog alert: 0.81 [within 20: 0.12] - ratio of genomes with paralogs Cluster includes: DDPB DDPC DPPB DPPC GSIC GSID NIKB NIKC OPPB OPPC SAPB SAPC YEJB YEJE |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 60_K | 64_Q | 3.808 | 1.00 | |
| 54_A | 59_D | 3.785 | 1.00 | |
| 28_H | 65_Q | 3.582 | 1.00 | |
| 60_K | 68_H | 3.514 | 1.00 | |
| 20_T | 66_Y | 3.389 | 1.00 | |
| 71_W | 75_H | 3.286 | 1.00 | |
| 33_D | 53_L | 3.231 | 1.00 | |
| 46_P | 50_A | 3.164 | 1.00 | |
| 67_L | 71_W | 3.072 | 1.00 | |
| 241_R | 247_R | 2.845 | 1.00 | |
| 21_L | 66_Y | 2.83 | 1.00 | |
| 98_A | 287_W | 2.666 | 1.00 | |
| 228_M | 255_A | 2.664 | 1.00 | |
| 237_I | 255_A | 2.659 | 1.00 | |
| 249_R | 253_V | 2.627 | 1.00 | |
| 264_V | 331_V | 2.575 | 1.00 | |
| 105_C | 209_A | 2.52 | 1.00 | |
| 63_W | 67_L | 2.505 | 1.00 | |
| 163_T | 206_I | 2.275 | 1.00 | |
| 91_E | 293_W | 2.23 | 1.00 | |
| 292_R | 296_D | 2.172 | 1.00 | |
| 268_G | 324_V | 2.144 | 1.00 | |
| 19_I | 314_A | 2.135 | 1.00 | |
| 109_F | 213_G | 2.133 | 1.00 | |
| 239_T | 243_K | 2.102 | 1.00 | |
| 163_T | 203_A | 2.1 | 1.00 | |
| 232_L | 255_A | 1.982 | 1.00 | |
| 265_T | 328_Y | 1.954 | 1.00 | |
| 72_G | 77_D | 1.946 | 1.00 | |
| 128_I | 132_T | 1.902 | 1.00 | |
| 3_Q | 7_R | 1.884 | 1.00 | |
| 73_V | 78_L | 1.848 | 1.00 | |
| 51_Q | 55_E | 1.839 | 1.00 | |
| 50_A | 54_A | 1.835 | 1.00 | |
| 87_P | 90_E | 1.829 | 1.00 | |
| 124_K | 127_S | 1.82 | 1.00 | |
| 64_Q | 68_H | 1.82 | 1.00 | |
| 16_F | 315_T | 1.8 | 1.00 | |
| 49_H | 53_L | 1.787 | 1.00 | |
| 20_T | 69_Y | 1.778 | 1.00 | |
| 48_R | 51_Q | 1.763 | 1.00 | |
| 112_A | 116_P | 1.757 | 1.00 | |
| 231_V | 236_Y | 1.754 | 1.00 | |
| 84_S | 91_E | 1.733 | 1.00 | |
| 86_I | 90_E | 1.729 | 1.00 | |
| 17_I | 21_L | 1.722 | 1.00 | |
| 152_L | 211_V | 1.711 | 1.00 | |
| 246_T | 249_R | 1.695 | 1.00 | |
| 327_L | 330_V | 1.685 | 1.00 | |
| 117_V | 133_A | 1.667 | 1.00 | |
| 157_S | 165_V | 1.659 | 1.00 | |
| 10_G | 14_P | 1.656 | 1.00 | |
| 89_W | 93_V | 1.644 | 1.00 | |
| 50_A | 53_L | 1.636 | 1.00 | |
| 88_V | 308_G | 1.621 | 1.00 | |
| 113_V | 116_P | 1.621 | 1.00 | |
| 12_V | 318_I | 1.605 | 1.00 | |
| 123_V | 251_I | 1.591 | 1.00 | |
| 297_A | 305_V | 1.59 | 1.00 | |
| 45_S | 48_R | 1.572 | 1.00 | |
| 155_L | 159_H | 1.565 | 1.00 | |
| 64_Q | 67_L | 1.553 | 1.00 | |
| 231_V | 234_E | 1.55 | 1.00 | |
| 236_Y | 258_N | 1.547 | 1.00 | |
| 213_G | 217_L | 1.544 | 1.00 | |
| 86_I | 94_P | 1.543 | 1.00 | |
| 248_M | 252_I | 1.526 | 1.00 | |
| 147_W | 151_M | 1.514 | 1.00 | |
| 154_M | 159_H | 1.505 | 1.00 | |
| 231_V | 237_I | 1.503 | 1.00 | |
| 122_A | 229_L | 1.502 | 1.00 | |
| 68_H | 71_W | 1.488 | 1.00 | |
| 17_I | 66_Y | 1.485 | 1.00 | |
| 35_V | 49_H | 1.483 | 1.00 | |
| 163_T | 207_L | 1.48 | 1.00 | |
| 243_K | 254_H | 1.478 | 1.00 | |
| 126_G | 130_D | 1.473 | 1.00 | |
| 235_D | 238_R | 1.47 | 1.00 | |
| 151_M | 155_L | 1.46 | 1.00 | |
| 57_G | 60_K | 1.46 | 1.00 | |
| 120_L | 124_K | 1.45 | 1.00 | |
| 61_P | 64_Q | 1.442 | 1.00 | |
| 130_D | 225_R | 1.427 | 1.00 | |
| 17_I | 70_I | 1.411 | 1.00 | |
| 231_V | 259_A | 1.397 | 0.99 | |
| 113_V | 217_L | 1.391 | 0.99 | |
| 140_G | 218_A | 1.391 | 0.99 | |
| 91_E | 305_V | 1.39 | 0.99 | |
| 294_L | 309_G | 1.385 | 0.99 | |
| 293_W | 305_V | 1.382 | 0.99 | |
| 32_G | 301_R | 1.38 | 0.99 | |
| 16_F | 318_I | 1.379 | 0.99 | |
| 21_L | 62_M | 1.371 | 0.99 | |
| 129_F | 133_A | 1.371 | 0.99 | |
| 237_I | 250_V | 1.369 | 0.99 | |
| 78_L | 308_G | 1.367 | 0.99 | |
| 12_V | 322_L | 1.357 | 0.99 | |
| 111_T | 267_I | 1.345 | 0.99 | |
| 261_L | 328_Y | 1.341 | 0.99 | |
| 120_L | 129_F | 1.336 | 0.99 | |
| 98_A | 101_E | 1.334 | 0.99 | |
| 6_L | 10_G | 1.328 | 0.99 | |
| 143_M | 148_W | 1.32 | 0.99 | |
| 209_A | 213_G | 1.318 | 0.99 | |
| 118_G | 224_T | 1.315 | 0.99 | |
| 110_A | 216_P | 1.307 | 0.99 | |
| 155_L | 160_W | 1.307 | 0.99 | |
| 148_W | 214_T | 1.304 | 0.99 | |
| 57_G | 68_H | 1.302 | 0.99 | |
| 133_A | 221_V | 1.276 | 0.99 | |
| 156_V | 160_W | 1.267 | 0.99 | |
| 119_V | 228_M | 1.264 | 0.99 | |
| 124_K | 129_F | 1.262 | 0.99 | |
| 309_G | 313_V | 1.259 | 0.99 | |
| 68_H | 72_G | 1.252 | 0.99 | |
| 326_L | 330_V | 1.25 | 0.99 | |
| 20_T | 311_L | 1.233 | 0.98 | |
| 323_L | 327_L | 1.229 | 0.98 | |
| 52_L | 56_L | 1.225 | 0.98 | |
| 152_L | 207_L | 1.219 | 0.98 | |
| 122_A | 228_M | 1.211 | 0.98 | |
| 21_L | 25_A | 1.209 | 0.98 | |
| 109_F | 209_A | 1.207 | 0.98 | |
| 202_V | 206_I | 1.198 | 0.98 | |
| 114_G | 220_I | 1.194 | 0.98 | |
| 28_H | 62_M | 1.187 | 0.98 | |
| 104_V | 108_I | 1.185 | 0.98 | |
| 149_G | 211_V | 1.176 | 0.98 | |
| 90_E | 93_V | 1.166 | 0.97 | |
| 126_G | 131_H | 1.161 | 0.97 | |
| 145_I | 281_T | 1.149 | 0.97 | |
| 66_Y | 70_I | 1.143 | 0.97 | |
| 101_E | 205_M | 1.14 | 0.97 | |
| 107_M | 267_I | 1.137 | 0.97 | |
| 118_G | 122_A | 1.124 | 0.97 | |
| 94_P | 97_Q | 1.118 | 0.96 | |
| 278_A | 281_T | 1.105 | 0.96 | |
| 206_I | 210_I | 1.103 | 0.96 | |
| 81_S | 302_D | 1.095 | 0.96 | |
| 60_K | 63_W | 1.091 | 0.96 | |
| 25_A | 62_M | 1.084 | 0.96 | |
| 4_F | 8_R | 1.082 | 0.96 | |
| 114_G | 224_T | 1.08 | 0.95 | |
| 39_A | 44_I | 1.079 | 0.95 | |
| 149_G | 284_I | 1.072 | 0.95 | |
| 86_I | 91_E | 1.068 | 0.95 | |
| 168_R | 287_W | 1.067 | 0.95 | |
| 122_A | 232_L | 1.058 | 0.95 | |
| 78_L | 89_W | 1.051 | 0.94 | |
| 52_L | 55_E | 1.048 | 0.94 | |
| 320_V | 324_V | 1.047 | 0.94 | |
| 5_I | 326_L | 1.043 | 0.94 | |
| 9_L | 322_L | 1.042 | 0.94 | |
| 54_A | 60_K | 1.042 | 0.94 | |
| 224_T | 263_V | 1.036 | 0.94 | |
| 73_V | 311_L | 1.029 | 0.94 | |
| 247_R | 250_V | 1.029 | 0.94 | |
| 4_F | 337_H | 1.023 | 0.93 | |
| 39_A | 52_L | 1.021 | 0.93 | |
| 71_W | 74_M | 1.015 | 0.93 | |
| 245_L | 250_V | 1.011 | 0.93 | |
| 245_L | 249_R | 1.008 | 0.93 | |
| 101_E | 168_R | 1.004 | 0.93 | |
| 223_M | 266_V | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3tuiA | 4 | 0.6195 | 99.9 | 0.761 | Contact Map | 0.726 |
| 3rlfF | 1 | 0.8614 | 99.8 | 0.777 | Contact Map | 0.528 |
| 2onkC | 4 | 0.7788 | 99.8 | 0.78 | Contact Map | 0.577 |
| 3d31C | 2 | 0.7876 | 99.7 | 0.792 | Contact Map | 0.546 |
| 3rlfG | 1 | 0.8289 | 99.6 | 0.82 | Contact Map | 0.403 |
| 3s82A | 2 | 0.2625 | 52 | 0.958 | Contact Map | 0.272 |
| 1p7lA | 4 | 0.2625 | 37.7 | 0.962 | Contact Map | 0.363 |
| 2p02A | 1 | 0.2478 | 31.8 | 0.963 | Contact Map | 0.279 |
| 3imlA | 4 | 0.2802 | 22.4 | 0.966 | Contact Map | 0.259 |
| 3so4A | 4 | 0.2714 | 15 | 0.969 | Contact Map | 0.253 |
Sequence Conservation (Image Generated using WebLogo v3)