May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

GSA - HEM2
UniProt: P23893 - P0ACB2
Length: 750
Sequences: 446
Seq/Len: 0.60
I_Prob: 0.00

GSA - Glutamate-1-semialdehyde 2,1-aminomutase
Paralog alert: 0.89 [within 20: 0.12] - ratio of genomes with paralogs
Cluster includes: ARGD ASTC BIOA GABT GSA PAT PUUE
HEM2 - Delta-aminolevulinic acid dehydratase
Paralog alert: 0.03 [within 20: 0.00] - ratio of genomes with paralogs
Cluster includes: HEM2
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
218_E 193_S 1.07 0.00
208_G 295_L 1.05 0.00
84_S 200_F 1.05 0.00
111_M 153_V 1.00 0.00
408_S 190_M 0.99 0.00
354_M 30_D 0.97 0.00
266_I 166_A 0.91 0.00
271_M 213_K 0.89 0.00
380_K 156_A 0.89 0.00
196_Q 256_V 0.88 0.00
241_T 269_A 0.88 0.00
348_V 20_M 0.88 0.00
348_V 144_L 0.87 0.00
67_N 154_A 0.87 0.00
354_M 298_L 0.86 0.00
368_Y 178_A 0.86 0.00
39_A 210_S 0.86 0.00
102_L 119_T 0.85 0.00
282_V 255_I 0.85 0.00
201_I 172_V 0.85 0.00
15_I 32_V 0.84 0.00
214_P 255_I 0.83 0.00
189_A 238_A 0.83 0.00
158_L 154_A 0.82 0.00
212_C 98_L 0.82 0.00
164_N 161_F 0.81 0.00
113_N 256_V 0.81 0.00
85_F 60_H 0.79 0.00
227_C 154_A 0.79 0.00
129_F 108_Q 0.79 0.00
386_M 117_S 0.78 0.00
208_G 302_K 0.78 0.00
185_A 260_R 0.77 0.00
218_E 50_M 0.77 0.00
62_M 208_A 0.77 0.00
76_I 26_L 0.77 0.00
107_D 255_I 0.77 0.00
67_N 117_S 0.76 0.00
208_G 210_S 0.76 0.00
8_Y 35_I 0.75 0.00
255_G 277_A 0.75 0.00
49_G 277_A 0.75 0.00
179_C 161_F 0.75 0.00
123_I 145_E 0.75 0.00
263_L 47_V 0.75 0.00
85_F 39_E 0.75 0.00
123_I 50_M 0.74 0.00
158_L 166_A 0.74 0.00
313_N 31_L 0.74 0.00
158_L 89_G 0.74 0.00
8_Y 133_L 0.74 0.00
266_I 171_Q 0.74 0.00
375_D 96_D 0.74 0.00
200_C 256_V 0.74 0.00
358_F 100_A 0.73 0.00
121_S 85_T 0.73 0.00
87_A 39_E 0.73 0.00
208_G 25_T 0.73 0.00
158_L 103_S 0.73 0.00
200_C 178_A 0.73 0.00
51_A 46_A 0.73 0.00
378_R 109_T 0.72 0.00
416_I 200_F 0.72 0.00
328_T 255_I 0.72 0.00
397_A 122_C 0.72 0.00
73_N 200_F 0.72 0.00
341_E 162_I 0.72 0.00
114_S 212_L 0.72 0.00
252_D 154_A 0.71 0.00
416_I 309_I 0.71 0.00
305_M 26_L 0.71 0.00
134_K 85_T 0.71 0.00
368_Y 114_I 0.71 0.00
111_M 75_S 0.71 0.00
106_M 35_I 0.71 0.00
224_R 175_I 0.71 0.00
348_V 249_A 0.71 0.00
388_D 32_V 0.71 0.00
131_G 148_G 0.71 0.00
262_C 47_V 0.70 0.00
136_I 27_S 0.70 0.00
394_A 81_I 0.70 0.00
13_E 58_E 0.70 0.00
350_H 307_D 0.70 0.00
186_S 260_R 0.70 0.00
79_A 117_S 0.69 0.00
44_L 106_C 0.69 0.00
136_I 26_L 0.69 0.00
136_I 75_S 0.69 0.00
217_P 174_A 0.69 0.00
55_Y 147_L 0.69 0.00
211_N 129_H 0.69 0.00
279_R 316_D 0.69 0.00
262_C 281_F 0.69 0.00
136_I 230_I 0.69 0.00
351_V 154_A 0.69 0.00
148_C 76_V 0.69 0.00
169_P 113_M 0.69 0.00
241_T 93_W 0.69 0.00
39_A 181_A 0.69 0.00
328_T 191_S 0.69 0.00
268_G 119_T 0.68 0.00
233_L 172_V 0.68 0.00
101_E 104_R 0.68 0.00
298_L 57_P 0.68 0.00
307_A 281_F 0.68 0.00
25_A 97_G 0.68 0.00
145_H 57_P 0.68 0.00
365_V 21_F 0.68 0.00
345_P 5_I 0.68 0.00
207_A 229_A 0.68 0.00
410_E 63_R 0.68 0.00
354_M 302_K 0.68 0.00
37_E 108_Q 0.68 0.00
97_Q 288_I 0.68 0.00
333_E 94_R 0.67 0.00
332_A 193_S 0.67 0.00
234_L 124_Y 0.67 0.00
420_R 74_R 0.67 0.00
99_V 244_L 0.67 0.00
385_M 277_A 0.67 0.00
162_Q 104_R 0.67 0.00
226_L 63_R 0.67 0.00
134_K 285_A 0.67 0.00
307_A 283_A 0.67 0.00
226_L 258_E 0.67 0.00
205_P 124_Y 0.67 0.00
166_P 319_E 0.67 0.00
160_L 8_P 0.66 0.00
192_E 255_I 0.66 0.00
400_A 316_D 0.66 0.00
391_V 261_E 0.66 0.00
379_F 249_A 0.66 0.00
129_F 277_A 0.66 0.00
417_D 70_N 0.66 0.00
56_V 229_A 0.66 0.00
53_I 65_I 0.66 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

Page generated in 0.1285 seconds.