May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
YDHX - Uncharacterized ferredoxin-like protein YdhX
UniProt: P77375 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13958
Length: 222 (210)
Sequences: 1106
Seq/Len: 5.27
YDHX
Paralog alert: 0.69 [within 20: 0.17] - ratio of genomes with paralogs
Cluster includes: DMSB HYCB HYDN HYFA NRFC YDHX YDHY YGFS YNFG YSAA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
109_S 139_R 2.743 1.00
59_T 157_S 2.732 1.00
197_Q 200_L 2.471 1.00
103_V 129_Y 2.352 1.00
165_P 168_V 2.331 1.00
40_I 186_I 2.331 1.00
98_A 111_R 2.197 1.00
39_M 153_F 2.121 1.00
112_D 160_A 2.063 1.00
128_S 141_L 1.931 1.00
38_A 181_E 1.918 1.00
120_E 123_Q 1.903 1.00
40_I 189_W 1.9 1.00
78_D 81_N 1.891 1.00
153_F 208_L 1.805 1.00
131_I 148_A 1.783 1.00
91_S 208_L 1.764 1.00
99_P 204_G 1.758 1.00
68_R 149_D 1.7 1.00
197_Q 205_K 1.624 0.99
101_I 109_S 1.578 0.99
128_S 131_I 1.524 0.99
96_E 207_H 1.522 0.99
112_D 116_I 1.516 0.99
43_E 89_R 1.496 0.99
46_C 52_C 1.484 0.99
190_L 195_Y 1.482 0.99
184_P 187_Q 1.474 0.98
46_C 49_C 1.47 0.98
91_S 176_L 1.467 0.98
142_N 149_D 1.465 0.98
41_H 176_L 1.462 0.98
116_I 159_L 1.442 0.98
46_C 171_C 1.437 0.98
104_C 124_C 1.433 0.98
69_L 176_L 1.407 0.98
103_V 133_A 1.401 0.98
49_C 171_C 1.393 0.98
49_C 52_C 1.387 0.97
90_Q 198_Y 1.372 0.97
197_Q 209_Y 1.331 0.97
104_C 130_C 1.329 0.96
52_C 171_C 1.327 0.96
124_C 130_C 1.327 0.96
47_N 173_E 1.318 0.96
109_S 119_V 1.305 0.96
168_V 176_L 1.303 0.96
96_E 205_K 1.299 0.96
187_Q 190_L 1.297 0.96
187_Q 191_Q 1.283 0.95
118_R 152_D 1.28 0.95
177_I 189_W 1.278 0.95
38_A 207_H 1.249 0.95
188_A 191_Q 1.239 0.94
35_V 180_R 1.236 0.94
55_A 170_A 1.232 0.94
158_R 163_F 1.22 0.94
48_G 175_A 1.213 0.93
10_L 17_F 1.212 0.93
190_L 209_Y 1.205 0.93
89_R 210_R 1.199 0.93
89_R 176_L 1.193 0.93
129_Y 132_G 1.186 0.92
158_R 162_G 1.182 0.92
36_R 96_E 1.171 0.92
18_F 23_S 1.148 0.91
164_P 168_V 1.144 0.90
185_E 188_A 1.134 0.90
36_R 182_D 1.128 0.90
158_R 169_S 1.127 0.90
188_A 192_Q 1.126 0.89
112_D 118_R 1.116 0.89
94_H 160_A 1.112 0.89
37_Y 159_L 1.103 0.88
23_S 27_A 1.099 0.88
180_R 183_S 1.098 0.88
106_T 125_I 1.096 0.88
152_D 157_S 1.091 0.87
15_V 24_S 1.087 0.87
17_F 20_G 1.087 0.87
103_V 139_R 1.084 0.87
36_R 207_H 1.079 0.87
98_A 101_I 1.075 0.86
186_I 190_L 1.071 0.86
121_K 147_V 1.064 0.86
57_R 62_V 1.063 0.86
106_T 109_S 1.062 0.85
41_H 89_R 1.054 0.85
60_N 157_S 1.046 0.84
18_F 27_A 1.043 0.84
186_I 189_W 1.039 0.84
20_G 23_S 1.033 0.83
12_M 21_S 1.028 0.83
176_L 198_Y 1.025 0.83
41_H 210_R 1.023 0.82
37_Y 94_H 1.007 0.81
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1ti6B60.83781000.426Contact Map0.658
2ivfB10.91441000.445Contact Map0.676
2vpzB20.83781000.491Contact Map0.733
1h0hB20.83781000.497Contact Map0.564
1kqfB10.93691000.503Contact Map0.612
1q16B10.86041000.574Contact Map0.675
3mm5B20.932499.70.759Contact Map0.29
3i9v920.621699.40.815Contact Map0.263
1jnrB20.603699.30.817Contact Map0.412
3gyxB60.603699.30.82Contact Map0.421
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 0.1665 seconds.