May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

HYDN - Electron transport protein HydN
UniProt: P0AAK4 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11552
Length: 175 (167)
Sequences: 2200
Seq/Len: 13.17

HYDN
Paralog alert: 0.63 [within 20: 0.30] - ratio of genomes with paralogs
Cluster includes: DMSB HYCB HYDN HYFA NRFC YDHX YDHY YGFS YNFG YSAA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
67_A 75_I 3.06 1.00
25_S 136_H 2.971 1.00
93_K 106_V 2.615 1.00
75_I 84_V 2.544 1.00
75_I 104_M 2.456 1.00
144_M 152_L 2.355 1.00
69_V 98_A 2.218 1.00
63_D 68_N 2.099 1.00
96_V 128_A 2.067 1.00
21_A 146_A 2.066 1.00
141_P 144_M 1.975 1.00
104_M 128_A 1.974 1.00
16_R 19_E 1.852 1.00
93_K 96_V 1.849 1.00
137_R 145_A 1.846 1.00
140_G 145_A 1.833 1.00
69_V 94_T 1.815 1.00
13_I 149_T 1.774 1.00
153_I 163_L 1.758 1.00
12_C 18_C 1.743 1.00
26_H 132_D 1.731 1.00
70_C 89_C 1.727 1.00
12_C 15_C 1.714 1.00
81_F 133_L 1.706 1.00
70_C 95_C 1.701 1.00
15_C 18_C 1.686 1.00
76_S 85_M 1.653 1.00
89_C 95_C 1.636 1.00
85_M 88_R 1.635 1.00
159_K 162_Q 1.598 1.00
42_P 46_V 1.596 1.00
106_V 128_A 1.55 1.00
7_A 152_L 1.542 1.00
7_A 55_A 1.502 1.00
163_L 166_E 1.471 1.00
71_P 90_I 1.43 1.00
72_N 90_I 1.415 1.00
162_Q 165_A 1.399 0.99
76_S 83_H 1.386 0.99
70_C 92_C 1.385 0.99
25_S 137_R 1.366 0.99
83_H 135_N 1.363 0.99
12_C 147_C 1.361 0.99
109_R 125_K 1.348 0.99
162_Q 166_E 1.342 0.99
163_L 167_K 1.32 0.99
15_C 147_C 1.296 0.99
140_G 144_M 1.296 0.99
92_C 95_C 1.287 0.99
65_P 98_A 1.279 0.99
89_C 92_C 1.273 0.99
8_D 11_K 1.26 0.99
57_V 152_L 1.239 0.98
41_L 44_I 1.22 0.98
18_C 147_C 1.217 0.98
9_A 55_A 1.217 0.98
93_K 128_A 1.216 0.98
138_E 154_C 1.202 0.98
72_N 75_I 1.167 0.97
40_F 43_R 1.163 0.97
157_R 161_E 1.156 0.97
155_V 159_K 1.146 0.97
14_G 17_T 1.144 0.97
132_D 136_H 1.132 0.97
5_I 133_L 1.108 0.96
64_A 67_A 1.103 0.96
64_A 77_R 1.102 0.96
81_F 138_E 1.101 0.96
11_K 151_A 1.1 0.96
115_S 120_N 1.092 0.96
17_T 146_A 1.084 0.96
86_Q 127_E 1.081 0.95
94_T 97_V 1.073 0.95
106_V 126_A 1.063 0.95
160_L 163_L 1.055 0.95
55_A 152_L 1.039 0.94
20_V 24_V 1.032 0.94
84_V 128_A 1.03 0.94
83_H 132_D 1.029 0.94
107_V 129_N 1.026 0.94
156_D 159_K 1.016 0.93
39_T 42_P 1.015 0.93
108_V 115_S 1.014 0.93
133_L 154_C 1.003 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1h0hB20.90861000.379Contact Map0.667
1ti6B60.90861000.38Contact Map0.664
1kqfB10.91431000.392Contact Map0.698
2ivfB10.91431000.401Contact Map0.694
2vpzB20.881000.434Contact Map0.692
1q16B10.914399.90.523Contact Map0.678
3mm5B20.914399.70.648Contact Map0.247
1rgvA10.445799.30.744Contact Map0.345
2fgoA10.451499.30.744Contact Map0.319
3eunA10.457199.30.746Contact Map0.282

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0158 seconds.