| UniProt: | P56256 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG14319 | ||
| Length: | 157 (153) | ||
| Sequences: | 2356 | ||
| Seq/Len: | 15.40 |
| YSAA
Paralog alert: 0.65 [within 20: 0.32] - ratio of genomes with paralogs Cluster includes: DMSB HYCB HYDN HYFA NRFC YDHX YDHY YGFS YNFG YSAA |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 67_A | 75_I | 3.069 | 1.00 | |
| 25_S | 123_H | 2.831 | 1.00 | |
| 93_K | 106_V | 2.638 | 1.00 | |
| 75_I | 84_V | 2.44 | 1.00 | |
| 131_V | 139_L | 2.412 | 1.00 | |
| 69_V | 98_A | 2.398 | 1.00 | |
| 128_P | 131_V | 2.254 | 1.00 | |
| 16_R | 19_E | 2.205 | 1.00 | |
| 76_S | 85_E | 2.18 | 1.00 | |
| 21_A | 133_A | 2.1 | 1.00 | |
| 96_M | 115_A | 2.065 | 1.00 | |
| 13_I | 136_T | 2.04 | 1.00 | |
| 63_D | 68_N | 2.036 | 1.00 | |
| 75_I | 104_M | 1.97 | 1.00 | |
| 69_V | 94_S | 1.959 | 1.00 | |
| 124_R | 132_E | 1.952 | 1.00 | |
| 26_H | 119_D | 1.933 | 1.00 | |
| 12_C | 15_C | 1.822 | 1.00 | |
| 93_K | 96_M | 1.821 | 1.00 | |
| 81_H | 120_L | 1.819 | 1.00 | |
| 15_C | 18_C | 1.799 | 1.00 | |
| 122_W | 126_T | 1.798 | 1.00 | |
| 12_C | 18_C | 1.791 | 1.00 | |
| 85_E | 88_R | 1.762 | 1.00 | |
| 64_A | 77_R | 1.74 | 1.00 | |
| 104_M | 115_A | 1.722 | 1.00 | |
| 140_Q | 150_H | 1.681 | 1.00 | |
| 70_C | 89_C | 1.656 | 1.00 | |
| 127_G | 132_E | 1.63 | 1.00 | |
| 70_C | 95_C | 1.62 | 1.00 | |
| 7_A | 139_L | 1.613 | 1.00 | |
| 78_E | 83_F | 1.606 | 1.00 | |
| 93_K | 115_A | 1.571 | 1.00 | |
| 89_C | 95_C | 1.568 | 1.00 | |
| 7_A | 55_A | 1.545 | 1.00 | |
| 146_K | 149_R | 1.537 | 1.00 | |
| 72_V | 90_I | 1.498 | 1.00 | |
| 78_E | 81_H | 1.491 | 1.00 | |
| 106_V | 115_A | 1.413 | 1.00 | |
| 71_P | 90_I | 1.402 | 0.99 | |
| 8_D | 11_K | 1.382 | 0.99 | |
| 76_S | 83_F | 1.371 | 0.99 | |
| 25_S | 124_R | 1.336 | 0.99 | |
| 107_V | 116_I | 1.308 | 0.99 | |
| 70_C | 92_C | 1.305 | 0.99 | |
| 144_V | 148_Q | 1.305 | 0.99 | |
| 72_V | 75_I | 1.285 | 0.99 | |
| 57_A | 139_L | 1.273 | 0.99 | |
| 12_C | 134_C | 1.271 | 0.99 | |
| 83_F | 122_W | 1.271 | 0.99 | |
| 93_K | 108_S | 1.26 | 0.99 | |
| 15_C | 134_C | 1.255 | 0.99 | |
| 17_T | 133_A | 1.254 | 0.99 | |
| 84_V | 115_A | 1.249 | 0.99 | |
| 150_H | 153_R | 1.248 | 0.99 | |
| 65_P | 98_A | 1.239 | 0.98 | |
| 119_D | 123_H | 1.215 | 0.98 | |
| 92_C | 95_C | 1.212 | 0.98 | |
| 143_D | 146_K | 1.212 | 0.98 | |
| 89_C | 92_C | 1.211 | 0.98 | |
| 13_I | 135_P | 1.209 | 0.98 | |
| 142_M | 146_K | 1.2 | 0.98 | |
| 127_G | 131_V | 1.197 | 0.98 | |
| 67_A | 77_R | 1.178 | 0.98 | |
| 18_C | 134_C | 1.177 | 0.98 | |
| 86_Q | 114_R | 1.177 | 0.98 | |
| 81_H | 125_E | 1.166 | 0.97 | |
| 107_V | 113_A | 1.164 | 0.97 | |
| 77_R | 82_I | 1.162 | 0.97 | |
| 125_E | 141_C | 1.159 | 0.97 | |
| 41_I | 44_I | 1.148 | 0.97 | |
| 94_S | 97_L | 1.135 | 0.97 | |
| 14_G | 17_T | 1.13 | 0.97 | |
| 60_Q | 82_I | 1.126 | 0.97 | |
| 9_A | 55_A | 1.112 | 0.96 | |
| 55_A | 139_L | 1.096 | 0.96 | |
| 64_A | 67_A | 1.083 | 0.96 | |
| 120_L | 141_C | 1.056 | 0.95 | |
| 32_C | 35_L | 1.042 | 0.94 | |
| 20_V | 24_V | 1.041 | 0.94 | |
| 9_A | 54_T | 1.04 | 0.94 | |
| 96_M | 106_V | 1.038 | 0.94 | |
| 149_R | 152_L | 1.027 | 0.94 | |
| 83_F | 119_D | 1.027 | 0.94 | |
| 78_E | 126_T | 1.026 | 0.94 | |
| 60_Q | 117_K | 1.024 | 0.93 | |
| 78_E | 122_W | 1.016 | 0.93 | |
| 42_S | 46_V | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1h0hB | 2 | 0.9809 | 100 | 0.341 | Contact Map | 0.67 |
| 1ti6B | 6 | 0.9809 | 100 | 0.352 | Contact Map | 0.685 |
| 1kqfB | 1 | 0.9873 | 100 | 0.353 | Contact Map | 0.724 |
| 2ivfB | 1 | 0.9873 | 100 | 0.375 | Contact Map | 0.699 |
| 2vpzB | 2 | 0.9363 | 100 | 0.403 | Contact Map | 0.687 |
| 1q16B | 1 | 0.9873 | 99.9 | 0.504 | Contact Map | 0.685 |
| 3mm5B | 2 | 0.9873 | 99.7 | 0.638 | Contact Map | 0.261 |
| 1rgvA | 1 | 0.4841 | 99.3 | 0.72 | Contact Map | 0.333 |
| 2fgoA | 1 | 0.4841 | 99.3 | 0.724 | Contact Map | 0.292 |
| 3eunA | 1 | 0.4841 | 99.2 | 0.726 | Contact Map | 0.256 |
Sequence Conservation (Image Generated using WebLogo v3)