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OPENSEQ.org
YNFG - Probable anaerobic dimethyl sulfoxide reductase chain YnfG
UniProt: P0AAJ1 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13845
Length: 205 (190)
Sequences: 1081
Seq/Len: 5.69
YNFG
Paralog alert: 0.64 [within 20: 0.04] - ratio of genomes with paralogs
Cluster includes: DMSB HYCB HYDN HYFA NRFC YDHX YDHY YGFS YNFG YSAA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
78_V 108_A 2.918 1.00
103_R 116_Y 2.58 1.00
76_T 84_M 2.474 1.00
73_P 86_K 2.442 1.00
27_F 131_S 2.386 1.00
116_Y 123_M 2.302 1.00
106_H 123_M 2.274 1.00
71_D 180_N 2.262 1.00
167_A 174_A 2.09 1.00
91_F 128_G 2.077 1.00
84_M 114_P 2.06 1.00
151_E 161_K 2.059 1.00
79_C 99_C 1.973 1.00
84_M 94_V 1.968 1.00
72_D 77_K 1.934 1.00
79_C 105_C 1.864 1.00
99_C 105_C 1.86 1.00
6_G 155_I 1.845 1.00
139_P 142_V 1.819 1.00
15_T 147_L 1.772 1.00
170_P 173_R 1.733 1.00
95_D 98_V 1.7 1.00
138_Q 143_E 1.669 1.00
138_Q 142_V 1.666 1.00
78_V 104_Y 1.64 1.00
23_A 144_S 1.616 0.99
7_F 128_G 1.596 0.99
64_S 150_L 1.563 0.99
117_N 124_T 1.557 0.99
130_Y 134_A 1.539 0.99
116_Y 121_G 1.525 0.99
66_S 150_L 1.507 0.99
38_R 115_Q 1.493 0.99
132_R 137_K 1.47 0.99
65_I 171_L 1.417 0.98
85_H 95_D 1.414 0.98
87_R 134_A 1.405 0.98
36_F 124_T 1.394 0.98
154_P 157_E 1.393 0.98
11_S 64_S 1.376 0.98
28_K 140_I 1.37 0.98
142_V 150_L 1.367 0.98
74_A 108_A 1.367 0.98
87_R 91_F 1.352 0.97
117_N 120_K 1.352 0.97
14_C 20_C 1.351 0.97
91_F 133_V 1.345 0.97
99_C 102_C 1.335 0.97
128_G 181_I 1.326 0.97
81_S 100_I 1.324 0.97
133_V 152_F 1.32 0.97
79_C 102_C 1.313 0.97
80_P 105_C 1.297 0.96
17_C 20_C 1.274 0.96
87_R 93_V 1.262 0.96
28_K 127_D 1.258 0.96
160_Q 163_G 1.253 0.95
14_C 17_C 1.25 0.95
159_R 164_T 1.248 0.95
27_F 132_R 1.244 0.95
80_P 99_C 1.239 0.95
9_I 150_L 1.22 0.94
100_I 104_Y 1.213 0.94
28_K 36_F 1.206 0.94
9_I 64_S 1.204 0.94
76_T 85_H 1.203 0.94
132_R 143_E 1.2 0.94
37_R 64_S 1.198 0.94
13_R 149_A 1.181 0.93
93_V 130_Y 1.179 0.93
160_Q 164_T 1.166 0.93
159_R 163_G 1.151 0.92
173_R 176_F 1.149 0.92
102_C 105_C 1.145 0.92
114_P 123_M 1.141 0.91
8_F 184_K 1.127 0.91
73_P 142_V 1.094 0.89
9_I 66_S 1.093 0.89
142_V 148_R 1.089 0.89
103_R 118_A 1.077 0.88
96_E 122_H 1.073 0.88
155_I 159_R 1.067 0.87
86_K 91_F 1.066 0.87
81_S 84_M 1.064 0.87
7_F 66_S 1.058 0.87
104_Y 107_M 1.057 0.87
46_D 49_E 1.056 0.87
159_R 162_H 1.054 0.86
78_V 107_M 1.032 0.85
116_Y 120_K 1.032 0.85
79_C 101_G 1.029 0.85
38_R 65_I 1.023 0.84
81_S 102_C 1.019 0.84
16_G 19_T 1.014 0.83
18_K 21_E 1.009 0.83
76_T 86_K 1.007 0.83
4_Q 155_I 1.007 0.83
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1ti6B60.94631000.387Contact Map0.669
2ivfB10.99021000.401Contact Map0.667
2vpzB20.93171000.457Contact Map0.647
1kqfB10.99021000.465Contact Map0.629
1h0hB20.94151000.465Contact Map0.617
1q16B10.99511000.52Contact Map0.652
3mm5B20.970799.80.727Contact Map0.229
3gyxB60.697699.30.805Contact Map0.353
1rgvA10.375699.30.811Contact Map0.279
2fgoA10.365999.20.814Contact Map0.237
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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