| UniProt: | Q46819 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13069 | ||
| Length: | 162 (156) | ||
| Sequences: | 2389 | ||
| Seq/Len: | 15.31 |
| YGFS
Paralog alert: 0.64 [within 20: 0.32] - ratio of genomes with paralogs Cluster includes: DMSB HYCB HYDN HYFA NRFC YDHX YDHY YGFS YNFG YSAA |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 64_V | 72_L | 3.145 | 1.00 | |
| 90_Q | 103_I | 2.686 | 1.00 | |
| 25_A | 122_Q | 2.45 | 1.00 | |
| 66_A | 95_A | 2.265 | 1.00 | |
| 130_V | 138_L | 2.249 | 1.00 | |
| 72_L | 101_I | 2.245 | 1.00 | |
| 16_R | 19_E | 2.151 | 1.00 | |
| 60_N | 65_G | 2.111 | 1.00 | |
| 73_T | 82_N | 2.109 | 1.00 | |
| 127_P | 130_V | 2.108 | 1.00 | |
| 21_A | 132_S | 2.051 | 1.00 | |
| 126_G | 131_E | 2.008 | 1.00 | |
| 61_A | 74_M | 1.98 | 1.00 | |
| 90_Q | 93_V | 1.904 | 1.00 | |
| 93_V | 114_I | 1.899 | 1.00 | |
| 101_I | 114_I | 1.89 | 1.00 | |
| 13_I | 135_T | 1.853 | 1.00 | |
| 26_H | 118_D | 1.827 | 1.00 | |
| 66_A | 91_S | 1.815 | 1.00 | |
| 123_R | 131_E | 1.777 | 1.00 | |
| 15_C | 18_C | 1.763 | 1.00 | |
| 82_N | 85_R | 1.762 | 1.00 | |
| 12_C | 18_C | 1.746 | 1.00 | |
| 12_C | 15_C | 1.729 | 1.00 | |
| 67_C | 86_C | 1.652 | 1.00 | |
| 67_C | 92_C | 1.61 | 1.00 | |
| 148_R | 151_Q | 1.608 | 1.00 | |
| 149_V | 152_Q | 1.596 | 1.00 | |
| 103_I | 114_I | 1.596 | 1.00 | |
| 86_C | 92_C | 1.579 | 1.00 | |
| 7_V | 138_L | 1.56 | 1.00 | |
| 68_P | 87_I | 1.537 | 1.00 | |
| 145_E | 148_R | 1.53 | 1.00 | |
| 72_L | 81_T | 1.495 | 1.00 | |
| 90_Q | 114_I | 1.466 | 1.00 | |
| 104_Q | 115_V | 1.454 | 1.00 | |
| 64_V | 74_M | 1.448 | 1.00 | |
| 38_L | 115_V | 1.436 | 1.00 | |
| 69_V | 87_I | 1.419 | 1.00 | |
| 4_L | 143_E | 1.401 | 0.99 | |
| 8_N | 11_D | 1.384 | 0.99 | |
| 69_V | 72_L | 1.361 | 0.99 | |
| 141_L | 145_E | 1.361 | 0.99 | |
| 7_V | 52_P | 1.349 | 0.99 | |
| 67_C | 89_C | 1.313 | 0.99 | |
| 139_Q | 149_V | 1.308 | 0.99 | |
| 54_M | 138_L | 1.304 | 0.99 | |
| 12_C | 133_C | 1.286 | 0.99 | |
| 62_P | 95_A | 1.277 | 0.99 | |
| 5_I | 119_L | 1.268 | 0.99 | |
| 15_C | 133_C | 1.262 | 0.99 | |
| 104_Q | 111_R | 1.254 | 0.99 | |
| 86_C | 89_C | 1.238 | 0.98 | |
| 89_C | 92_C | 1.232 | 0.98 | |
| 121_E | 125_E | 1.224 | 0.98 | |
| 149_V | 153_R | 1.211 | 0.98 | |
| 39_P | 43_V | 1.186 | 0.98 | |
| 18_C | 133_C | 1.184 | 0.98 | |
| 104_Q | 110_T | 1.183 | 0.98 | |
| 17_T | 132_S | 1.174 | 0.98 | |
| 25_A | 123_R | 1.163 | 0.97 | |
| 143_E | 147_R | 1.161 | 0.97 | |
| 83_S | 113_Q | 1.16 | 0.97 | |
| 59_E | 74_M | 1.158 | 0.97 | |
| 126_G | 130_V | 1.134 | 0.97 | |
| 142_T | 145_E | 1.133 | 0.97 | |
| 75_G | 80_Q | 1.122 | 0.97 | |
| 148_R | 152_Q | 1.11 | 0.96 | |
| 152_Q | 156_A | 1.094 | 0.96 | |
| 103_I | 112_Q | 1.09 | 0.96 | |
| 13_I | 134_P | 1.088 | 0.96 | |
| 75_G | 125_E | 1.088 | 0.96 | |
| 104_Q | 112_Q | 1.087 | 0.96 | |
| 91_S | 94_S | 1.084 | 0.96 | |
| 75_G | 78_V | 1.069 | 0.95 | |
| 150_R | 153_R | 1.062 | 0.95 | |
| 61_A | 64_V | 1.059 | 0.95 | |
| 152_Q | 155_V | 1.052 | 0.95 | |
| 75_G | 121_E | 1.047 | 0.94 | |
| 93_V | 103_I | 1.046 | 0.94 | |
| 119_L | 140_L | 1.041 | 0.94 | |
| 118_D | 122_Q | 1.033 | 0.94 | |
| 14_G | 17_T | 1.023 | 0.93 | |
| 57_Q | 116_K | 1.021 | 0.93 | |
| 83_S | 111_R | 1.02 | 0.93 | |
| 90_Q | 105_S | 1.008 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1ti6B | 6 | 0.9691 | 100 | 0.327 | Contact Map | 0.649 |
| 1kqfB | 1 | 0.9753 | 100 | 0.338 | Contact Map | 0.703 |
| 1h0hB | 2 | 0.9691 | 100 | 0.339 | Contact Map | 0.632 |
| 2ivfB | 1 | 0.9753 | 100 | 0.353 | Contact Map | 0.679 |
| 2vpzB | 2 | 0.9444 | 100 | 0.39 | Contact Map | 0.653 |
| 1q16B | 1 | 0.9753 | 99.9 | 0.505 | Contact Map | 0.645 |
| 3mm5B | 2 | 0.9753 | 99.7 | 0.624 | Contact Map | 0.277 |
| 1rgvA | 1 | 0.4877 | 99.2 | 0.725 | Contact Map | 0.395 |
| 2fgoA | 1 | 0.4753 | 99.2 | 0.727 | Contact Map | 0.339 |
| 3eunA | 1 | 0.5 | 99.2 | 0.73 | Contact Map | 0.296 |
Sequence Conservation (Image Generated using WebLogo v3)