| UniProt: | P77300 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13349 | ||
| Length: | 252 (248) | ||
| Sequences: | 5282 | ||
| Seq/Len: | 21.30 |
| YAGI
Paralog alert: 0.70 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: ALLR ICLR KDGR MHPR RHMR YAGI YIAJ YJHI |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 7_V | 10_A | 3.286 | 1.00 | |
| 88_W | 240_A | 3.032 | 1.00 | |
| 103_G | 139_I | 2.544 | 1.00 | |
| 98_Q | 224_R | 2.484 | 1.00 | |
| 95_R | 236_Q | 2.468 | 1.00 | |
| 11_L | 52_Y | 2.461 | 1.00 | |
| 8_E | 50_H | 2.458 | 1.00 | |
| 15_D | 67_K | 2.362 | 1.00 | |
| 181_Q | 185_Q | 2.326 | 1.00 | |
| 109_E | 131_R | 2.324 | 1.00 | |
| 153_N | 176_M | 2.32 | 1.00 | |
| 17_F | 53_I | 2.267 | 1.00 | |
| 141_K | 193_E | 2.23 | 1.00 | |
| 86_K | 114_E | 2.148 | 1.00 | |
| 203_V | 237_L | 2.136 | 1.00 | |
| 229_E | 232_N | 2.02 | 1.00 | |
| 190_D | 200_C | 2.01 | 1.00 | |
| 105_L | 134_V | 1.993 | 1.00 | |
| 12_Q | 50_H | 1.988 | 1.00 | |
| 141_K | 178_A | 1.977 | 1.00 | |
| 44_L | 53_I | 1.924 | 1.00 | |
| 13_I | 29_I | 1.918 | 1.00 | |
| 191_S | 199_R | 1.898 | 1.00 | |
| 16_L | 33_M | 1.809 | 1.00 | |
| 165_T | 168_T | 1.794 | 1.00 | |
| 91_E | 243_A | 1.788 | 1.00 | |
| 91_E | 95_R | 1.777 | 1.00 | |
| 16_L | 29_I | 1.745 | 1.00 | |
| 147_L | 151_E | 1.725 | 1.00 | |
| 199_R | 222_T | 1.72 | 1.00 | |
| 93_S | 100_T | 1.717 | 1.00 | |
| 29_I | 40_L | 1.714 | 1.00 | |
| 218_L | 233_F | 1.708 | 1.00 | |
| 15_D | 50_H | 1.706 | 1.00 | |
| 146_W | 206_W | 1.689 | 1.00 | |
| 88_W | 243_A | 1.687 | 1.00 | |
| 220_T | 225_V | 1.675 | 1.00 | |
| 56_N | 59_N | 1.65 | 1.00 | |
| 110_G | 134_V | 1.642 | 1.00 | |
| 90_T | 116_I | 1.59 | 1.00 | |
| 48_Q | 53_I | 1.589 | 1.00 | |
| 117_E | 123_I | 1.579 | 1.00 | |
| 24_L | 32_L | 1.578 | 1.00 | |
| 88_W | 247_A | 1.557 | 1.00 | |
| 25_K | 28_D | 1.542 | 1.00 | |
| 234_R | 238_Q | 1.532 | 1.00 | |
| 15_D | 52_Y | 1.528 | 1.00 | |
| 152_L | 176_M | 1.515 | 1.00 | |
| 89_L | 100_T | 1.496 | 1.00 | |
| 17_F | 24_L | 1.491 | 1.00 | |
| 192_E | 222_T | 1.49 | 1.00 | |
| 203_V | 241_G | 1.475 | 1.00 | |
| 54_D | 63_R | 1.446 | 1.00 | |
| 171_S | 174_A | 1.437 | 1.00 | |
| 106_D | 131_R | 1.412 | 1.00 | |
| 192_E | 197_G | 1.412 | 1.00 | |
| 85_A | 244_L | 1.404 | 0.99 | |
| 82_R | 114_E | 1.4 | 0.99 | |
| 238_Q | 242_L | 1.386 | 0.99 | |
| 178_A | 181_Q | 1.374 | 0.99 | |
| 26_I | 41_H | 1.372 | 0.99 | |
| 135_H | 168_T | 1.371 | 0.99 | |
| 92_L | 240_A | 1.37 | 0.99 | |
| 136_A | 168_T | 1.355 | 0.99 | |
| 146_W | 204_P | 1.355 | 0.99 | |
| 16_L | 24_L | 1.346 | 0.99 | |
| 17_F | 23_E | 1.326 | 0.99 | |
| 187_Y | 234_R | 1.322 | 0.99 | |
| 44_L | 62_Y | 1.321 | 0.99 | |
| 148_G | 151_E | 1.316 | 0.99 | |
| 23_E | 63_R | 1.315 | 0.99 | |
| 88_W | 91_E | 1.308 | 0.99 | |
| 110_G | 143_L | 1.307 | 0.99 | |
| 145_A | 182_T | 1.304 | 0.99 | |
| 11_L | 50_H | 1.301 | 0.99 | |
| 206_W | 245_S | 1.291 | 0.99 | |
| 102_L | 214_A | 1.289 | 0.99 | |
| 203_V | 238_Q | 1.276 | 0.99 | |
| 108_R | 158_G | 1.272 | 0.99 | |
| 102_L | 205_V | 1.266 | 0.99 | |
| 105_L | 108_R | 1.265 | 0.99 | |
| 149_E | 180_A | 1.257 | 0.99 | |
| 96_T | 236_Q | 1.255 | 0.99 | |
| 206_W | 212_V | 1.255 | 0.99 | |
| 179_L | 182_T | 1.254 | 0.99 | |
| 144_I | 175_L | 1.252 | 0.99 | |
| 89_L | 102_L | 1.251 | 0.99 | |
| 137_T | 140_G | 1.249 | 0.99 | |
| 36_S | 39_T | 1.244 | 0.98 | |
| 41_H | 45_K | 1.238 | 0.98 | |
| 93_S | 116_I | 1.234 | 0.98 | |
| 85_A | 102_L | 1.234 | 0.98 | |
| 172_R | 176_M | 1.228 | 0.98 | |
| 103_G | 110_G | 1.227 | 0.98 | |
| 29_I | 44_L | 1.221 | 0.98 | |
| 182_T | 185_Q | 1.213 | 0.98 | |
| 182_T | 188_A | 1.212 | 0.98 | |
| 203_V | 234_R | 1.206 | 0.98 | |
| 89_L | 216_L | 1.205 | 0.98 | |
| 239_Q | 243_A | 1.2 | 0.98 | |
| 241_G | 245_S | 1.198 | 0.98 | |
| 67_K | 70_E | 1.198 | 0.98 | |
| 92_L | 236_Q | 1.193 | 0.98 | |
| 30_S | 40_L | 1.184 | 0.98 | |
| 5_Q | 9_R | 1.178 | 0.98 | |
| 35_L | 40_L | 1.165 | 0.97 | |
| 221_L | 224_R | 1.162 | 0.97 | |
| 35_L | 39_T | 1.157 | 0.97 | |
| 169_L | 178_A | 1.155 | 0.97 | |
| 152_L | 183_R | 1.15 | 0.97 | |
| 16_L | 32_L | 1.138 | 0.97 | |
| 207_N | 211_R | 1.134 | 0.97 | |
| 95_R | 239_Q | 1.117 | 0.96 | |
| 245_S | 250_Y | 1.116 | 0.96 | |
| 13_I | 33_M | 1.111 | 0.96 | |
| 153_N | 172_R | 1.106 | 0.96 | |
| 96_T | 218_L | 1.106 | 0.96 | |
| 201_V | 234_R | 1.103 | 0.96 | |
| 204_P | 212_V | 1.099 | 0.96 | |
| 216_L | 244_L | 1.096 | 0.96 | |
| 200_C | 217_S | 1.096 | 0.96 | |
| 138_A | 202_A | 1.09 | 0.96 | |
| 68_L | 75_V | 1.081 | 0.95 | |
| 96_T | 233_F | 1.081 | 0.95 | |
| 149_E | 176_M | 1.08 | 0.95 | |
| 86_K | 90_T | 1.077 | 0.95 | |
| 27_T | 31_K | 1.072 | 0.95 | |
| 202_A | 217_S | 1.07 | 0.95 | |
| 136_A | 164_F | 1.067 | 0.95 | |
| 178_A | 182_T | 1.056 | 0.95 | |
| 20_Q | 32_L | 1.038 | 0.94 | |
| 167_A | 192_E | 1.034 | 0.94 | |
| 111_V | 131_R | 1.024 | 0.93 | |
| 104_I | 214_A | 1.024 | 0.93 | |
| 192_E | 196_Q | 1.024 | 0.93 | |
| 27_T | 37_K | 1.015 | 0.93 | |
| 48_Q | 55_Q | 1.006 | 0.93 | |
| 200_C | 219_S | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3mq0A | 2 | 0.9921 | 100 | 0.062 | Contact Map | 0.754 |
| 2ia2A | 4 | 0.9921 | 100 | 0.064 | Contact Map | 0.843 |
| 2g7uA | 4 | 0.9921 | 100 | 0.066 | Contact Map | 0.812 |
| 3r4kA | 4 | 0.9881 | 100 | 0.067 | Contact Map | 0.799 |
| 1mkmA | 2 | 0.9881 | 100 | 0.071 | Contact Map | 0.887 |
| 2xrnA | 2 | 0.9563 | 100 | 0.089 | Contact Map | 0.763 |
| 2o0yA | 4 | 0.9643 | 100 | 0.116 | Contact Map | 0.781 |
| 1ysqA | 1 | 0.7183 | 100 | 0.377 | Contact Map | 0.828 |
| 1tf1A | 4 | 0.7778 | 100 | 0.38 | Contact Map | 0.881 |
| 1yspA | 1 | 0.6984 | 100 | 0.384 | Contact Map | 0.891 |
Sequence Conservation (Image Generated using WebLogo v3)