| UniProt: | P0ACN4 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13616 | ||
| Length: | 271 (250) | ||
| Sequences: | 5182 | ||
| Seq/Len: | 20.73 |
| ALLR
Paralog alert: 0.70 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: ALLR ICLR KDGR MHPR RHMR YAGI YIAJ YJHI |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 24_L | 27_G | 3.305 | 1.00 | |
| 105_F | 257_T | 3.017 | 1.00 | |
| 120_A | 156_A | 2.534 | 1.00 | |
| 115_E | 241_R | 2.527 | 1.00 | |
| 28_I | 69_F | 2.493 | 1.00 | |
| 25_E | 67_A | 2.426 | 1.00 | |
| 112_L | 253_L | 2.394 | 1.00 | |
| 32_Q | 84_G | 2.364 | 1.00 | |
| 198_Q | 202_L | 2.325 | 1.00 | |
| 158_K | 210_E | 2.324 | 1.00 | |
| 170_M | 193_L | 2.302 | 1.00 | |
| 34_L | 70_V | 2.274 | 1.00 | |
| 126_E | 148_R | 2.236 | 1.00 | |
| 103_G | 131_G | 2.18 | 1.00 | |
| 220_S | 254_V | 2.157 | 1.00 | |
| 122_R | 151_L | 2.055 | 1.00 | |
| 158_K | 195_D | 2.024 | 1.00 | |
| 207_D | 217_C | 2.008 | 1.00 | |
| 29_A | 67_A | 2 | 1.00 | |
| 61_L | 70_V | 1.977 | 1.00 | |
| 30_I | 46_I | 1.949 | 1.00 | |
| 208_K | 216_N | 1.923 | 1.00 | |
| 246_R | 249_S | 1.862 | 1.00 | |
| 182_T | 185_T | 1.832 | 1.00 | |
| 33_Y | 50_L | 1.787 | 1.00 | |
| 33_Y | 46_I | 1.754 | 1.00 | |
| 46_I | 57_T | 1.74 | 1.00 | |
| 108_R | 260_D | 1.731 | 1.00 | |
| 216_N | 239_S | 1.728 | 1.00 | |
| 163_P | 223_Y | 1.716 | 1.00 | |
| 110_M | 117_V | 1.714 | 1.00 | |
| 108_R | 112_L | 1.711 | 1.00 | |
| 32_Q | 67_A | 1.694 | 1.00 | |
| 235_I | 250_Q | 1.68 | 1.00 | |
| 164_L | 168_E | 1.677 | 1.00 | |
| 105_F | 260_D | 1.671 | 1.00 | |
| 73_D | 76_L | 1.655 | 1.00 | |
| 237_G | 242_L | 1.649 | 1.00 | |
| 127_A | 151_L | 1.613 | 1.00 | |
| 134_E | 140_R | 1.603 | 1.00 | |
| 41_S | 49_N | 1.595 | 1.00 | |
| 65_Q | 70_V | 1.588 | 1.00 | |
| 105_F | 264_A | 1.587 | 1.00 | |
| 107_R | 133_L | 1.574 | 1.00 | |
| 32_Q | 69_F | 1.562 | 1.00 | |
| 42_S | 45_D | 1.561 | 1.00 | |
| 251_G | 255_R | 1.549 | 1.00 | |
| 34_L | 41_S | 1.533 | 1.00 | |
| 220_S | 258_A | 1.526 | 1.00 | |
| 209_E | 239_S | 1.499 | 1.00 | |
| 106_M | 117_V | 1.496 | 1.00 | |
| 102_A | 261_I | 1.493 | 1.00 | |
| 169_L | 193_L | 1.488 | 1.00 | |
| 71_Y | 80_H | 1.458 | 1.00 | |
| 188_D | 191_T | 1.422 | 1.00 | |
| 123_N | 148_R | 1.406 | 0.99 | |
| 152_H | 185_T | 1.403 | 0.99 | |
| 209_E | 214_G | 1.402 | 0.99 | |
| 99_L | 131_G | 1.398 | 0.99 | |
| 165_A | 168_E | 1.389 | 0.99 | |
| 153_A | 185_T | 1.38 | 0.99 | |
| 109_L | 257_T | 1.378 | 0.99 | |
| 255_R | 259_R | 1.377 | 0.99 | |
| 43_V | 58_F | 1.377 | 0.99 | |
| 262_S | 267_L | 1.371 | 0.99 | |
| 195_D | 198_Q | 1.351 | 0.99 | |
| 33_Y | 41_S | 1.338 | 0.99 | |
| 127_A | 160_L | 1.335 | 0.99 | |
| 163_P | 221_A | 1.331 | 0.99 | |
| 61_L | 79_W | 1.325 | 0.99 | |
| 125_N | 175_Q | 1.324 | 0.99 | |
| 166_E | 197_E | 1.313 | 0.99 | |
| 223_Y | 262_S | 1.312 | 0.99 | |
| 106_M | 119_V | 1.306 | 0.99 | |
| 196_L | 199_A | 1.299 | 0.99 | |
| 162_Y | 199_A | 1.297 | 0.99 | |
| 220_S | 255_R | 1.291 | 0.99 | |
| 223_Y | 229_V | 1.29 | 0.99 | |
| 161_L | 192_L | 1.289 | 0.99 | |
| 119_V | 231_A | 1.285 | 0.99 | |
| 119_V | 222_I | 1.284 | 0.99 | |
| 258_A | 262_S | 1.276 | 0.99 | |
| 199_A | 202_L | 1.267 | 0.99 | |
| 28_I | 67_A | 1.265 | 0.99 | |
| 58_F | 62_K | 1.263 | 0.99 | |
| 34_L | 40_S | 1.254 | 0.99 | |
| 113_S | 253_L | 1.253 | 0.99 | |
| 110_M | 133_L | 1.25 | 0.99 | |
| 102_A | 119_V | 1.245 | 0.98 | |
| 106_M | 233_I | 1.241 | 0.98 | |
| 46_I | 61_L | 1.233 | 0.98 | |
| 105_F | 108_R | 1.231 | 0.98 | |
| 204_Y | 251_G | 1.23 | 0.98 | |
| 47_S | 57_T | 1.229 | 0.98 | |
| 122_R | 125_N | 1.228 | 0.98 | |
| 256_D | 260_D | 1.22 | 0.98 | |
| 189_M | 193_L | 1.218 | 0.98 | |
| 154_S | 157_G | 1.217 | 0.98 | |
| 220_S | 251_G | 1.209 | 0.98 | |
| 22_Q | 26_R | 1.199 | 0.98 | |
| 53_P | 56_T | 1.197 | 0.98 | |
| 120_A | 127_A | 1.187 | 0.98 | |
| 186_L | 195_D | 1.185 | 0.98 | |
| 40_S | 80_H | 1.185 | 0.98 | |
| 84_G | 87_N | 1.184 | 0.98 | |
| 224_D | 228_S | 1.181 | 0.98 | |
| 199_A | 205_T | 1.18 | 0.98 | |
| 33_Y | 49_N | 1.179 | 0.98 | |
| 238_P | 241_R | 1.174 | 0.98 | |
| 52_L | 56_T | 1.166 | 0.97 | |
| 169_L | 200_R | 1.161 | 0.97 | |
| 52_L | 57_T | 1.157 | 0.97 | |
| 30_I | 50_L | 1.141 | 0.97 | |
| 103_G | 107_R | 1.134 | 0.97 | |
| 109_L | 253_L | 1.132 | 0.97 | |
| 113_S | 235_I | 1.127 | 0.97 | |
| 170_M | 189_M | 1.111 | 0.96 | |
| 221_A | 229_V | 1.11 | 0.96 | |
| 219_A | 234_S | 1.109 | 0.96 | |
| 217_C | 234_S | 1.094 | 0.96 | |
| 195_D | 199_A | 1.088 | 0.96 | |
| 209_E | 213_V | 1.076 | 0.95 | |
| 166_E | 193_L | 1.075 | 0.95 | |
| 37_S | 49_N | 1.073 | 0.95 | |
| 184_T | 209_E | 1.072 | 0.95 | |
| 85_V | 92_Y | 1.065 | 0.95 | |
| 155_G | 219_A | 1.064 | 0.95 | |
| 180_Q | 187_V | 1.063 | 0.95 | |
| 112_L | 256_D | 1.061 | 0.95 | |
| 233_I | 261_I | 1.05 | 0.94 | |
| 44_S | 48_L | 1.048 | 0.94 | |
| 113_S | 250_Q | 1.047 | 0.94 | |
| 153_A | 181_F | 1.038 | 0.94 | |
| 218_I | 251_G | 1.03 | 0.94 | |
| 128_V | 148_R | 1.028 | 0.94 | |
| 65_Q | 72_Q | 1.027 | 0.94 | |
| 31_L | 85_V | 1.023 | 0.93 | |
| 163_P | 229_V | 1.02 | 0.93 | |
| 44_S | 54_L | 1.015 | 0.93 | |
| 217_C | 236_S | 1.011 | 0.93 | |
| 50_L | 57_T | 1.003 | 0.93 | |
| 155_G | 217_C | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2ia2A | 4 | 0.9742 | 100 | 0.106 | Contact Map | 0.841 |
| 2g7uA | 4 | 0.941 | 100 | 0.116 | Contact Map | 0.811 |
| 3mq0A | 2 | 0.9852 | 100 | 0.116 | Contact Map | 0.749 |
| 3r4kA | 4 | 0.9262 | 100 | 0.122 | Contact Map | 0.798 |
| 1mkmA | 2 | 0.9188 | 100 | 0.124 | Contact Map | 0.885 |
| 2xrnA | 2 | 0.8893 | 100 | 0.144 | Contact Map | 0.756 |
| 2o0yA | 4 | 0.9483 | 100 | 0.172 | Contact Map | 0.782 |
| 1tf1A | 4 | 0.7306 | 100 | 0.407 | Contact Map | 0.881 |
| 1ysqA | 1 | 0.6753 | 100 | 0.409 | Contact Map | 0.83 |
| 1yspA | 1 | 0.6568 | 100 | 0.411 | Contact Map | 0.895 |
Sequence Conservation (Image Generated using WebLogo v3)