| UniProt: | P39360 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12551 | ||
| Length: | 262 (248) | ||
| Sequences: | 5248 | ||
| Seq/Len: | 21.16 |
| YJHI
Paralog alert: 0.70 [within 20: 0.11] - ratio of genomes with paralogs Cluster includes: ALLR ICLR KDGR MHPR RHMR YAGI YIAJ YJHI |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 9_L | 12_A | 3.274 | 1.00 | |
| 88_P | 241_C | 3.077 | 1.00 | |
| 103_G | 140_L | 2.594 | 1.00 | |
| 98_L | 225_V | 2.52 | 1.00 | |
| 13_E | 53_F | 2.474 | 1.00 | |
| 95_K | 237_L | 2.467 | 1.00 | |
| 154_D | 177_L | 2.416 | 1.00 | |
| 10_V | 51_C | 2.394 | 1.00 | |
| 17_T | 67_K | 2.348 | 1.00 | |
| 182_K | 186_R | 2.348 | 1.00 | |
| 142_K | 194_E | 2.327 | 1.00 | |
| 109_S | 132_K | 2.324 | 1.00 | |
| 19_I | 54_L | 2.324 | 1.00 | |
| 86_K | 114_D | 2.157 | 1.00 | |
| 204_M | 238_L | 2.142 | 1.00 | |
| 230_K | 233_S | 2.066 | 1.00 | |
| 105_M | 135_L | 2.032 | 1.00 | |
| 142_K | 179_E | 2.032 | 1.00 | |
| 191_D | 201_C | 2.026 | 1.00 | |
| 45_L | 54_L | 1.961 | 1.00 | |
| 192_N | 200_V | 1.95 | 1.00 | |
| 14_K | 51_C | 1.936 | 1.00 | |
| 15_I | 30_L | 1.912 | 1.00 | |
| 166_T | 169_T | 1.857 | 1.00 | |
| 91_E | 244_Q | 1.789 | 1.00 | |
| 91_E | 95_K | 1.787 | 1.00 | |
| 200_V | 223_P | 1.785 | 1.00 | |
| 18_H | 34_F | 1.781 | 1.00 | |
| 148_K | 152_E | 1.772 | 1.00 | |
| 88_P | 244_Q | 1.743 | 1.00 | |
| 18_H | 30_L | 1.734 | 1.00 | |
| 30_L | 41_L | 1.733 | 1.00 | |
| 147_W | 207_F | 1.713 | 1.00 | |
| 17_T | 51_C | 1.701 | 1.00 | |
| 93_S | 100_C | 1.7 | 1.00 | |
| 219_L | 234_Y | 1.673 | 1.00 | |
| 110_A | 135_L | 1.666 | 1.00 | |
| 117_E | 124_T | 1.649 | 1.00 | |
| 221_G | 226_Y | 1.647 | 1.00 | |
| 90_Q | 116_I | 1.589 | 1.00 | |
| 235_L | 239_R | 1.584 | 1.00 | |
| 88_P | 248_G | 1.581 | 1.00 | |
| 25_A | 33_K | 1.565 | 1.00 | |
| 49_V | 54_L | 1.55 | 1.00 | |
| 204_M | 242_A | 1.539 | 1.00 | |
| 89_M | 100_C | 1.525 | 1.00 | |
| 153_L | 177_L | 1.498 | 1.00 | |
| 55_I | 63_S | 1.49 | 1.00 | |
| 17_T | 53_F | 1.481 | 1.00 | |
| 193_E | 223_P | 1.473 | 1.00 | |
| 19_I | 25_A | 1.473 | 1.00 | |
| 193_E | 198_G | 1.468 | 1.00 | |
| 85_T | 245_I | 1.467 | 1.00 | |
| 26_S | 29_E | 1.46 | 1.00 | |
| 172_D | 175_L | 1.44 | 1.00 | |
| 239_R | 243_E | 1.412 | 1.00 | |
| 106_E | 132_K | 1.405 | 0.99 | |
| 82_F | 114_D | 1.404 | 0.99 | |
| 137_I | 169_T | 1.401 | 0.99 | |
| 246_S | 251_Y | 1.401 | 0.99 | |
| 92_L | 241_C | 1.39 | 0.99 | |
| 147_W | 205_P | 1.389 | 0.99 | |
| 136_H | 169_T | 1.386 | 0.99 | |
| 27_Y | 42_L | 1.38 | 0.99 | |
| 110_A | 144_L | 1.343 | 0.99 | |
| 149_T | 152_E | 1.341 | 0.99 | |
| 179_E | 182_K | 1.34 | 0.99 | |
| 45_L | 62_Y | 1.328 | 0.99 | |
| 102_L | 215_Y | 1.325 | 0.99 | |
| 13_E | 51_C | 1.304 | 0.99 | |
| 180_L | 183_T | 1.302 | 0.99 | |
| 138_T | 141_G | 1.3 | 0.99 | |
| 42_L | 46_N | 1.296 | 0.99 | |
| 146_A | 183_T | 1.294 | 0.99 | |
| 207_F | 246_S | 1.284 | 0.99 | |
| 207_F | 213_V | 1.281 | 0.99 | |
| 145_L | 176_F | 1.28 | 0.99 | |
| 102_L | 206_V | 1.277 | 0.99 | |
| 96_S | 237_L | 1.277 | 0.99 | |
| 105_M | 108_I | 1.273 | 0.99 | |
| 188_W | 235_L | 1.268 | 0.99 | |
| 89_M | 102_L | 1.267 | 0.99 | |
| 173_K | 177_L | 1.266 | 0.99 | |
| 204_M | 239_R | 1.266 | 0.99 | |
| 108_I | 159_A | 1.26 | 0.99 | |
| 37_P | 40_S | 1.252 | 0.99 | |
| 85_T | 102_L | 1.25 | 0.99 | |
| 18_H | 25_A | 1.25 | 0.99 | |
| 150_R | 181_Q | 1.243 | 0.98 | |
| 242_A | 246_S | 1.243 | 0.98 | |
| 183_T | 189_A | 1.241 | 0.98 | |
| 88_P | 91_E | 1.24 | 0.98 | |
| 30_L | 45_L | 1.237 | 0.98 | |
| 222_D | 225_V | 1.236 | 0.98 | |
| 240_K | 244_Q | 1.234 | 0.98 | |
| 92_L | 237_L | 1.234 | 0.98 | |
| 183_T | 186_R | 1.233 | 0.98 | |
| 89_M | 217_I | 1.232 | 0.98 | |
| 93_S | 116_I | 1.225 | 0.98 | |
| 31_L | 41_L | 1.224 | 0.98 | |
| 103_G | 110_A | 1.217 | 0.98 | |
| 204_M | 235_L | 1.211 | 0.98 | |
| 67_K | 70_E | 1.208 | 0.98 | |
| 36_Y | 40_S | 1.2 | 0.98 | |
| 153_L | 184_R | 1.19 | 0.98 | |
| 36_Y | 41_L | 1.178 | 0.98 | |
| 18_H | 33_K | 1.155 | 0.97 | |
| 19_I | 24_M | 1.151 | 0.97 | |
| 208_N | 212_R | 1.147 | 0.97 | |
| 170_F | 179_E | 1.146 | 0.97 | |
| 96_S | 219_L | 1.146 | 0.97 | |
| 7_N | 11_R | 1.131 | 0.97 | |
| 86_K | 90_Q | 1.117 | 0.96 | |
| 154_D | 173_K | 1.115 | 0.96 | |
| 202_L | 235_L | 1.115 | 0.96 | |
| 15_I | 34_F | 1.114 | 0.96 | |
| 203_S | 218_S | 1.108 | 0.96 | |
| 68_N | 75_A | 1.108 | 0.96 | |
| 205_P | 213_V | 1.1 | 0.96 | |
| 168_N | 193_E | 1.098 | 0.96 | |
| 137_I | 165_H | 1.095 | 0.96 | |
| 96_S | 234_Y | 1.093 | 0.96 | |
| 24_M | 63_S | 1.093 | 0.96 | |
| 28_M | 32_N | 1.086 | 0.96 | |
| 139_A | 203_S | 1.084 | 0.96 | |
| 150_R | 177_L | 1.082 | 0.96 | |
| 95_K | 240_K | 1.076 | 0.95 | |
| 201_C | 218_S | 1.076 | 0.95 | |
| 217_I | 245_I | 1.07 | 0.95 | |
| 193_E | 197_Y | 1.065 | 0.95 | |
| 104_A | 215_Y | 1.056 | 0.95 | |
| 150_R | 184_R | 1.055 | 0.95 | |
| 179_E | 183_T | 1.04 | 0.94 | |
| 9_L | 44_L | 1.032 | 0.94 | |
| 28_M | 38_K | 1.021 | 0.93 | |
| 88_P | 245_I | 1.016 | 0.93 | |
| 49_V | 56_K | 1.015 | 0.93 | |
| 157_L | 173_K | 1.012 | 0.93 | |
| 158_E | 173_K | 1.012 | 0.93 | |
| 201_C | 220_S | 1.012 | 0.93 | |
| 111_I | 132_K | 1.007 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2g7uA | 4 | 0.958 | 100 | 0.124 | Contact Map | 0.812 |
| 3mq0A | 2 | 0.9695 | 100 | 0.126 | Contact Map | 0.754 |
| 2ia2A | 4 | 0.9618 | 100 | 0.126 | Contact Map | 0.849 |
| 1mkmA | 2 | 0.9466 | 100 | 0.137 | Contact Map | 0.885 |
| 3r4kA | 4 | 0.9771 | 100 | 0.144 | Contact Map | 0.797 |
| 2xrnA | 2 | 0.9122 | 100 | 0.165 | Contact Map | 0.763 |
| 2o0yA | 4 | 0.9389 | 100 | 0.175 | Contact Map | 0.772 |
| 1ysqA | 1 | 0.7252 | 100 | 0.415 | Contact Map | 0.817 |
| 1tf1A | 4 | 0.7557 | 100 | 0.419 | Contact Map | 0.869 |
| 3obfA | 2 | 0.6718 | 100 | 0.424 | Contact Map | 0.705 |
Sequence Conservation (Image Generated using WebLogo v3)