| UniProt: | P76539 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG14168 | ||
| Length: | 141 (135) | ||
| Sequences: | 12464 | ||
| Seq/Len: | 92.33 |
| YPEA
Paralog alert: 0.86 [within 20: 0.21] - ratio of genomes with paralogs Cluster includes: ATDA PHNO RIMI RIMJ RIML YAFP YEDL YHHY YIAC YJAB YJGM YNCA YPEA |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 4_R | 49_E | 3.615 | 1.00 | |
| 4_R | 10_D | 2.704 | 1.00 | |
| 20_R | 75_H | 2.571 | 1.00 | |
| 85_N | 121_L | 2.48 | 1.00 | |
| 92_E | 123_Y | 2.434 | 1.00 | |
| 58_V | 91_L | 2.384 | 1.00 | |
| 48_A | 83_I | 2.308 | 1.00 | |
| 92_E | 133_K | 2.251 | 1.00 | |
| 85_N | 120_R | 2.203 | 1.00 | |
| 90_R | 93_K | 2.158 | 1.00 | |
| 46_L | 90_R | 2.141 | 1.00 | |
| 55_V | 78_F | 2.088 | 1.00 | |
| 115_L | 119_E | 2.005 | 1.00 | |
| 47_V | 54_V | 2.004 | 1.00 | |
| 6_F | 14_V | 1.936 | 1.00 | |
| 89_N | 121_L | 1.83 | 1.00 | |
| 94_K | 98_R | 1.825 | 1.00 | |
| 50_V | 55_V | 1.761 | 1.00 | |
| 94_K | 97_A | 1.749 | 1.00 | |
| 78_F | 81_R | 1.724 | 1.00 | |
| 88_L | 121_L | 1.71 | 1.00 | |
| 92_E | 103_I | 1.665 | 1.00 | |
| 12_E | 31_E | 1.651 | 1.00 | |
| 116_G | 119_E | 1.638 | 1.00 | |
| 56_G | 74_V | 1.624 | 1.00 | |
| 13_E | 16_T | 1.609 | 1.00 | |
| 90_R | 94_K | 1.592 | 1.00 | |
| 107_V | 111_N | 1.557 | 1.00 | |
| 50_V | 78_F | 1.52 | 1.00 | |
| 119_E | 125_H | 1.485 | 1.00 | |
| 50_V | 81_R | 1.465 | 1.00 | |
| 105_I | 118_Y | 1.464 | 1.00 | |
| 85_N | 89_N | 1.459 | 1.00 | |
| 60_G | 91_L | 1.44 | 1.00 | |
| 13_E | 54_V | 1.44 | 1.00 | |
| 112_D | 116_G | 1.421 | 1.00 | |
| 53_D | 75_H | 1.352 | 0.99 | |
| 46_L | 94_K | 1.334 | 0.99 | |
| 31_E | 35_E | 1.333 | 0.99 | |
| 53_D | 77_E | 1.329 | 0.99 | |
| 67_G | 95_L | 1.328 | 0.99 | |
| 8_Q | 35_E | 1.314 | 0.99 | |
| 49_E | 52_G | 1.286 | 0.99 | |
| 16_T | 20_R | 1.268 | 0.99 | |
| 20_R | 76_P | 1.229 | 0.98 | |
| 79_R | 113_M | 1.222 | 0.98 | |
| 45_F | 59_M | 1.22 | 0.98 | |
| 49_E | 54_V | 1.209 | 0.98 | |
| 82_G | 85_N | 1.2 | 0.98 | |
| 16_T | 75_H | 1.181 | 0.98 | |
| 2_E | 49_E | 1.179 | 0.98 | |
| 75_H | 78_F | 1.149 | 0.97 | |
| 93_K | 97_A | 1.146 | 0.97 | |
| 15_I | 19_E | 1.128 | 0.97 | |
| 18_W | 57_T | 1.127 | 0.97 | |
| 74_V | 83_I | 1.122 | 0.97 | |
| 58_V | 87_L | 1.113 | 0.96 | |
| 6_F | 47_V | 1.088 | 0.96 | |
| 95_L | 103_I | 1.084 | 0.96 | |
| 44_L | 98_R | 1.082 | 0.96 | |
| 112_D | 115_L | 1.076 | 0.95 | |
| 68_S | 104_Q | 1.064 | 0.95 | |
| 114_V | 118_Y | 1.054 | 0.95 | |
| 88_L | 123_Y | 1.04 | 0.94 | |
| 60_G | 95_L | 1.034 | 0.94 | |
| 13_E | 17_L | 1.031 | 0.94 | |
| 10_D | 49_E | 1.028 | 0.94 | |
| 21_C | 73_G | 1.014 | 0.93 | |
| 13_E | 53_D | 1.014 | 0.93 | |
| 55_V | 83_I | 1.005 | 0.93 | |
| 86_A | 90_R | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2pdoA | 8 | 1 | 99.9 | 0.216 | Contact Map | 0.864 |
| 1s3zA | 2 | 0.9574 | 99.8 | 0.234 | Contact Map | 0.741 |
| 4evyA | 2 | 0.9574 | 99.8 | 0.25 | Contact Map | 0.722 |
| 3dr6A | 3 | 1 | 99.8 | 0.254 | Contact Map | 0.853 |
| 3fynA | 1 | 1 | 99.8 | 0.262 | Contact Map | 0.68 |
| 2oh1A | 4 | 0.9645 | 99.8 | 0.265 | Contact Map | 0.709 |
| 2j8mA | 2 | 1 | 99.8 | 0.269 | Contact Map | 0.717 |
| 3fixA | 4 | 0.9574 | 99.8 | 0.276 | Contact Map | 0.802 |
| 4kvxA | 2 | 0.9645 | 99.8 | 0.277 | Contact Map | 0.758 |
| 1ufhA | 2 | 0.9504 | 99.8 | 0.277 | Contact Map | 0.56 |
Sequence Conservation (Image Generated using WebLogo v3)