| UniProt: | P13857 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10853 | ||
| Length: | 179 (172) | ||
| Sequences: | 10636 | ||
| Seq/Len: | 61.84 |
| RIML
Paralog alert: 0.87 [within 20: 0.17] - ratio of genomes with paralogs Cluster includes: ATDA PHNO RIMI RIMJ RIML YAFP YEDL YHHY YIAC YJAB YJGM YNCA YPEA |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 111_S | 147_R | 3.43 | 1.00 | |
| 14_H | 73_F | 3.2 | 1.00 | |
| 14_H | 20_H | 2.988 | 1.00 | |
| 152_L | 155_C | 2.638 | 1.00 | |
| 132_I | 145_A | 2.606 | 1.00 | |
| 153_E | 173_A | 2.538 | 1.00 | |
| 143_Q | 146_L | 2.345 | 1.00 | |
| 152_L | 170_N | 2.197 | 1.00 | |
| 22_K | 48_E | 2.135 | 1.00 | |
| 10_S | 112_Q | 2.109 | 1.00 | |
| 119_H | 123_Q | 2.014 | 1.00 | |
| 118_I | 130_F | 1.983 | 1.00 | |
| 84_F | 121_Y | 1.861 | 1.00 | |
| 134_C | 142_N | 1.854 | 1.00 | |
| 118_I | 150_F | 1.846 | 1.00 | |
| 134_C | 145_A | 1.83 | 1.00 | |
| 94_A | 127_L | 1.803 | 1.00 | |
| 116_A | 119_H | 1.8 | 1.00 | |
| 142_N | 146_L | 1.795 | 1.00 | |
| 136_V | 168_D | 1.786 | 1.00 | |
| 71_M | 78_L | 1.776 | 1.00 | |
| 8_S | 116_A | 1.772 | 1.00 | |
| 146_L | 152_L | 1.77 | 1.00 | |
| 8_S | 112_Q | 1.756 | 1.00 | |
| 16_V | 71_M | 1.739 | 1.00 | |
| 79_I | 104_H | 1.714 | 1.00 | |
| 82_I | 117_L | 1.681 | 1.00 | |
| 129_R | 173_A | 1.663 | 1.00 | |
| 128_R | 158_Q | 1.654 | 1.00 | |
| 121_Y | 130_F | 1.648 | 1.00 | |
| 158_Q | 177_D | 1.632 | 1.00 | |
| 161_F | 166_Y | 1.621 | 1.00 | |
| 155_C | 170_N | 1.612 | 1.00 | |
| 142_N | 170_N | 1.608 | 1.00 | |
| 96_I | 114_L | 1.555 | 1.00 | |
| 100_L | 110_I | 1.515 | 1.00 | |
| 114_L | 148_N | 1.508 | 1.00 | |
| 118_I | 174_R | 1.451 | 1.00 | |
| 142_N | 152_L | 1.45 | 1.00 | |
| 155_C | 168_D | 1.439 | 1.00 | |
| 48_E | 52_R | 1.431 | 1.00 | |
| 47_S | 50_D | 1.4 | 0.99 | |
| 111_S | 148_N | 1.399 | 0.99 | |
| 34_W | 102_E | 1.398 | 0.99 | |
| 111_S | 144_V | 1.388 | 0.99 | |
| 101_D | 104_H | 1.374 | 0.99 | |
| 77_E | 103_S | 1.368 | 0.99 | |
| 23_P | 78_L | 1.362 | 0.99 | |
| 82_I | 113_A | 1.362 | 0.99 | |
| 142_N | 172_Y | 1.359 | 0.99 | |
| 18_E | 56_Q | 1.354 | 0.99 | |
| 129_R | 153_E | 1.31 | 0.99 | |
| 139_P | 142_N | 1.298 | 0.99 | |
| 137_D | 167_D | 1.296 | 0.99 | |
| 23_P | 77_E | 1.287 | 0.99 | |
| 136_V | 170_N | 1.286 | 0.99 | |
| 120_H | 124_S | 1.273 | 0.99 | |
| 141_S | 145_A | 1.268 | 0.99 | |
| 115_Q | 148_N | 1.26 | 0.99 | |
| 32_K | 102_E | 1.255 | 0.99 | |
| 23_P | 26_Q | 1.254 | 0.99 | |
| 21_V | 55_V | 1.248 | 0.99 | |
| 12_E | 73_F | 1.227 | 0.98 | |
| 74_K | 79_I | 1.207 | 0.98 | |
| 98_Y | 145_A | 1.205 | 0.98 | |
| 136_V | 155_C | 1.2 | 0.98 | |
| 122_A | 176_I | 1.2 | 0.98 | |
| 156_L | 171_L | 1.199 | 0.98 | |
| 72_I | 113_A | 1.189 | 0.98 | |
| 81_V | 99_W | 1.167 | 0.97 | |
| 105_Q | 140_Q | 1.159 | 0.97 | |
| 98_Y | 141_S | 1.15 | 0.97 | |
| 139_P | 143_Q | 1.14 | 0.97 | |
| 22_K | 26_Q | 1.136 | 0.97 | |
| 152_L | 172_Y | 1.122 | 0.97 | |
| 18_E | 52_R | 1.122 | 0.97 | |
| 73_F | 76_D | 1.114 | 0.96 | |
| 74_K | 107_Q | 1.114 | 0.96 | |
| 120_H | 125_G | 1.109 | 0.96 | |
| 52_R | 56_Q | 1.104 | 0.96 | |
| 100_L | 109_I | 1.103 | 0.96 | |
| 159_A | 169_V | 1.102 | 0.96 | |
| 158_Q | 168_D | 1.093 | 0.96 | |
| 8_S | 11_L | 1.08 | 0.95 | |
| 25_Y | 48_E | 1.076 | 0.95 | |
| 128_R | 166_Y | 1.063 | 0.95 | |
| 53_K | 57_G | 1.06 | 0.95 | |
| 150_F | 174_R | 1.056 | 0.95 | |
| 145_A | 150_F | 1.052 | 0.95 | |
| 72_I | 100_L | 1.048 | 0.94 | |
| 84_F | 117_L | 1.043 | 0.94 | |
| 111_S | 115_Q | 1.04 | 0.94 | |
| 95_E | 133_K | 1.031 | 0.94 | |
| 102_E | 105_Q | 1.018 | 0.93 | |
| 118_I | 148_N | 1.018 | 0.93 | |
| 54_T | 58_N | 1.016 | 0.93 | |
| 16_V | 24_L | 1.011 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3r9fA | 2 | 0.9888 | 100 | 0.222 | Contact Map | 0.799 |
| 1s7kA | 1 | 1 | 100 | 0.24 | Contact Map | 0.766 |
| 1nslA | 6 | 0.9944 | 100 | 0.248 | Contact Map | 0.913 |
| 2fckA | 1 | 0.9777 | 100 | 0.252 | Contact Map | 0.806 |
| 2vzyA | 4 | 0.9832 | 100 | 0.265 | Contact Map | 0.76 |
| 2z10A | 1 | 0.9665 | 100 | 0.268 | Contact Map | 0.787 |
| 3pzjA | 2 | 0.9665 | 100 | 0.268 | Contact Map | 0.777 |
| 1yreA | 4 | 0.9441 | 99.9 | 0.271 | Contact Map | 0.775 |
| 3fbuA | 2 | 0.9274 | 99.9 | 0.297 | Contact Map | 0.867 |
| 3igrA | 2 | 0.9944 | 99.9 | 0.304 | Contact Map | 0.809 |
Sequence Conservation (Image Generated using WebLogo v3)