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OPENSEQ.org

YJGM - Uncharacterized N-acetyltransferase YjgM
UniProt: P39337 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12532
Length: 167 (161)
Sequences: 13864
Seq/Len: 86.11

YJGM
Paralog alert: 0.86 [within 20: 0.23] - ratio of genomes with paralogs
Cluster includes: ATDA PHNO RIMI RIMJ RIML YAFP YEDL YHHY YIAC YJAB YJGM YNCA YPEA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
12_R 66_E 3.731 1.00
113_M 144_F 2.893 1.00
28_Q 96_L 2.749 1.00
75_G 112_A 2.675 1.00
12_R 18_D 2.625 1.00
106_K 142_L 2.565 1.00
111_M 114_E 2.529 1.00
106_K 141_H 2.491 1.00
72_V 99_I 2.38 1.00
65_V 104_L 2.349 1.00
113_M 165_R 2.34 1.00
140_E 146_H 2.212 1.00
136_I 140_E 2.18 1.00
64_V 71_V 2.174 1.00
63_W 111_M 2.165 1.00
115_Q 119_M 2.085 1.00
115_Q 118_E 2.007 1.00
109_A 142_L 2.006 1.00
123_R 164_L 1.938 1.00
110_L 142_L 1.928 1.00
113_M 124_C 1.904 1.00
67_Y 72_V 1.861 1.00
73_G 95_F 1.762 1.00
137_A 140_E 1.704 1.00
21_A 24_R 1.695 1.00
14_L 22_I 1.69 1.00
126_L 139_Y 1.683 1.00
111_M 115_Q 1.631 1.00
99_I 102_K 1.594 1.00
67_Y 102_K 1.586 1.00
70_E 98_A 1.578 1.00
67_Y 99_I 1.545 1.00
106_K 110_L 1.541 1.00
88_C 116_A 1.517 1.00
146_H 149_Y 1.517 1.00
77_I 112_A 1.483 1.00
66_E 71_V 1.457 1.00
63_W 115_Q 1.454 1.00
66_E 69_G 1.438 1.00
62_Y 76_G 1.434 1.00
128_T 132_L 1.434 1.00
136_I 146_H 1.416 1.00
114_E 118_E 1.397 0.99
61_A 119_M 1.386 0.99
10_V 66_E 1.385 0.99
21_A 71_V 1.367 0.99
133_K 137_A 1.365 0.99
70_E 96_L 1.353 0.99
147_I 164_L 1.32 0.99
20_P 48_L 1.308 0.99
16_L 52_Y 1.29 0.99
103_G 106_K 1.264 0.99
135_A 139_Y 1.26 0.99
88_C 121_F 1.259 0.99
75_G 108_L 1.23 0.98
24_R 96_L 1.224 0.98
96_L 99_I 1.205 0.98
100_R 134_E 1.205 0.98
95_F 104_L 1.2 0.98
77_I 116_A 1.174 0.98
14_L 64_V 1.157 0.97
128_T 135_A 1.136 0.97
72_V 104_L 1.124 0.97
107_K 111_M 1.119 0.96
133_K 136_I 1.116 0.96
13_R 115_Q 1.102 0.96
146_H 161_V 1.099 0.96
28_Q 97_P 1.092 0.96
130_A 159_C 1.087 0.96
13_R 61_A 1.085 0.96
65_V 108_L 1.085 0.96
79_P 121_F 1.082 0.96
29_V 94_Y 1.08 0.95
24_R 28_Q 1.078 0.95
48_L 52_Y 1.069 0.95
23_A 27_R 1.067 0.95
116_A 124_C 1.063 0.95
65_V 73_G 1.055 0.95
90_L 109_A 1.049 0.94
21_A 25_V 1.043 0.94
130_A 149_Y 1.04 0.94
113_M 117_R 1.039 0.94
14_L 62_Y 1.038 0.94
114_E 117_R 1.033 0.94
26_I 74_G 1.031 0.94
18_D 66_E 1.028 0.94
27_R 31_A 1.008 0.93
11_M 111_M 1.005 0.93
149_Y 159_C 1.004 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2j8mA20.952199.90.247Contact Map0.753
3dr6A30.958199.90.256Contact Map0.866
4e2aA2199.90.261Contact Map0.784
3d8pA20.934199.90.278Contact Map0.758
1tiqA20.964199.80.286Contact Map0.755
3kkwA10.964199.80.287Contact Map0.703
4l8aA10.940199.80.288Contact Map0.714
2oh1A40.946199.80.292Contact Map0.715
4j3gA40.98899.80.296Contact Map0.837
2ob0A30.910299.80.3Contact Map0.819

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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