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YDHJ - Uncharacterized protein YdhJ
UniProt: P76185 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13944
Length: 285 (260)
Sequences: 11915
Seq/Len: 45.83
YDHJ
Paralog alert: 0.82 [within 20: 0.24] - ratio of genomes with paralogs
Cluster includes: AAEA ACRA ACRE EMRA EMRK MACA MDTA MDTE MDTN YBHG YDHJ YHII YIAV YIBH
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
57_E 74_T 3.496 1.00
67_N 159_S 3.297 1.00
71_L 153_E 3.172 1.00
88_Q 146_Q 2.757 1.00
221_G 262_F 2.694 1.00
102_N 106_N 2.561 1.00
224_S 263_A 2.517 1.00
207_P 220_Q 2.481 1.00
109_R 125_N 2.452 1.00
108_R 116_I 2.392 1.00
108_R 124_A 2.364 1.00
74_T 153_E 2.364 1.00
67_N 70_D 2.363 1.00
84_E 142_L 2.323 1.00
77_K 81_Q 2.32 1.00
125_N 129_K 2.274 1.00
59_N 74_T 2.268 1.00
50_Q 151_Q 2.222 1.00
41_R 191_I 2.087 1.00
71_L 155_R 2.055 1.00
59_N 71_L 2.051 1.00
112_S 121_L 1.98 1.00
98_L 128_V 1.948 1.00
209_Q 218_T 1.924 1.00
105_A 121_L 1.905 1.00
40_I 190_V 1.903 1.00
136_D 139_Q 1.891 1.00
68_A 159_S 1.887 1.00
118_A 122_D 1.879 1.00
209_Q 220_Q 1.877 1.00
65_L 161_W 1.869 1.00
85_L 88_Q 1.84 1.00
91_L 142_L 1.831 1.00
207_P 222_H 1.799 1.00
105_A 109_R 1.79 1.00
208_A 262_F 1.77 1.00
143_K 146_Q 1.763 1.00
102_N 128_V 1.757 1.00
112_S 118_A 1.751 1.00
81_Q 149_L 1.75 1.00
192_G 262_F 1.729 1.00
100_K 104_E 1.716 1.00
81_Q 85_L 1.708 1.00
120_E 123_T 1.67 1.00
95_Q 139_Q 1.669 1.00
102_N 132_Q 1.668 1.00
189_Y 261_R 1.65 1.00
163_T 183_V 1.64 1.00
156_A 182_L 1.638 1.00
105_A 128_V 1.632 1.00
91_L 135_V 1.63 1.00
222_H 263_A 1.615 1.00
84_E 146_Q 1.609 1.00
222_H 265_D 1.603 1.00
128_V 132_Q 1.594 1.00
192_G 281_I 1.588 1.00
84_E 88_Q 1.578 1.00
98_L 102_N 1.566 1.00
88_Q 142_L 1.561 1.00
55_I 73_L 1.514 1.00
80_F 152_T 1.501 1.00
86_N 141_T 1.447 1.00
55_I 167_T 1.445 1.00
129_K 132_Q 1.432 1.00
191_I 259_P 1.426 1.00
105_A 125_N 1.415 1.00
53_G 75_I 1.411 1.00
61_K 64_Q 1.41 1.00
121_L 125_N 1.405 0.99
106_N 109_R 1.391 0.99
104_E 123_T 1.362 0.99
190_V 279_C 1.361 0.99
144_Q 148_Q 1.357 0.99
225_S 261_R 1.351 0.99
146_Q 150_A 1.342 0.99
195_E 198_K 1.336 0.99
230_I 258_V 1.331 0.99
99_A 102_N 1.325 0.99
83_A 148_Q 1.295 0.99
64_Q 70_D 1.29 0.99
212_L 279_C 1.286 0.99
87_A 138_A 1.281 0.99
83_A 144_Q 1.277 0.99
107_R 122_D 1.275 0.99
139_Q 143_K 1.274 0.99
57_E 169_I 1.271 0.99
209_Q 282_A 1.269 0.99
56_V 76_D 1.266 0.99
40_I 188_F 1.257 0.99
162_V 180_F 1.251 0.99
84_E 149_L 1.245 0.98
99_A 103_N 1.244 0.98
72_L 180_F 1.227 0.98
89_A 140_A 1.227 0.98
91_L 139_Q 1.225 0.98
187_S 263_A 1.217 0.98
211_T 282_A 1.212 0.98
65_L 185_S 1.209 0.98
93_K 134_S 1.203 0.98
174_D 177_K 1.201 0.98
190_V 281_I 1.2 0.98
109_R 121_L 1.188 0.98
184_D 187_S 1.171 0.98
142_L 146_Q 1.167 0.97
99_A 129_K 1.166 0.97
46_S 178_P 1.16 0.97
106_N 110_H 1.16 0.97
73_L 154_I 1.159 0.97
58_L 169_I 1.155 0.97
71_L 74_T 1.15 0.97
56_V 74_T 1.146 0.97
88_Q 92_A 1.143 0.97
49_P 154_I 1.142 0.97
85_L 143_K 1.138 0.97
156_A 159_S 1.135 0.97
223_V 260_V 1.13 0.97
95_Q 99_A 1.117 0.96
191_I 261_R 1.117 0.96
123_T 127_N 1.109 0.96
160_G 182_L 1.103 0.96
97_D 130_A 1.1 0.96
83_A 86_N 1.099 0.96
119_E 123_T 1.097 0.96
91_L 95_Q 1.095 0.96
60_I 70_D 1.09 0.96
100_K 123_T 1.085 0.96
210_I 264_L 1.081 0.95
165_L 168_R 1.073 0.95
97_D 100_K 1.069 0.95
73_L 180_F 1.065 0.95
110_H 113_Q 1.06 0.95
127_N 130_A 1.059 0.95
73_L 179_L 1.053 0.95
217_K 272_T 1.047 0.94
60_I 180_F 1.044 0.94
104_E 119_E 1.042 0.94
50_Q 54_R 1.039 0.94
38_G 279_C 1.039 0.94
227_G 259_P 1.037 0.94
103_N 122_D 1.037 0.94
147_W 151_Q 1.025 0.93
55_I 173_A 1.017 0.93
90_Q 141_T 1.015 0.93
98_L 132_Q 1.014 0.93
122_D 125_N 1.008 0.93
101_A 131_M 1.002 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2f1mA40.83861000.274Contact Map0.745
3fppA20.87721000.317Contact Map0.756
4dk0A10.94041000.319Contact Map0.642
3lnnA20.90531000.32Contact Map0.708
1vf7A130.86321000.355Contact Map0.813
4l8jA10.83161000.361Contact Map0.775
3ne5B20.82811000.376Contact Map0.743
4kkuA40.63861000.48Contact Map0.792
2k32A10.499.80.609Contact Map0.627
2dneA10.354499.60.702Contact Map0.651
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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