| UniProt: | P75777 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13315 | ||
| Length: | 332 (323) | ||
| Sequences: | 6720 | ||
| Seq/Len: | 20.80 |
| YBHG
Paralog alert: 0.80 [within 20: 0.13] - ratio of genomes with paralogs Cluster includes: AAEA ACRA ACRE EMRA EMRK MACA MDTA MDTE MDTN YBHG YDHJ YHII YIAV YIBH |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 67_K | 212_D | 4.041 | 1.00 | |
| 57_S | 74_E | 3.848 | 1.00 | |
| 275_G | 306_I | 3.411 | 1.00 | |
| 71_V | 206_T | 3.409 | 1.00 | |
| 84_L | 195_L | 3.129 | 1.00 | |
| 88_K | 199_E | 3.047 | 1.00 | |
| 135_Q | 152_R | 2.923 | 1.00 | |
| 260_K | 274_H | 2.707 | 1.00 | |
| 67_K | 70_Q | 2.694 | 1.00 | |
| 278_G | 307_V | 2.596 | 1.00 | |
| 95_Q | 192_Q | 2.558 | 1.00 | |
| 128_Q | 132_N | 2.537 | 1.00 | |
| 91_V | 188_L | 2.494 | 1.00 | |
| 135_Q | 139_K | 2.435 | 1.00 | |
| 74_E | 206_T | 2.415 | 1.00 | |
| 134_Q | 143_I | 2.405 | 1.00 | |
| 77_H | 81_E | 2.387 | 1.00 | |
| 71_V | 208_I | 2.302 | 1.00 | |
| 260_K | 276_Q | 2.242 | 1.00 | |
| 128_Q | 159_Q | 2.171 | 1.00 | |
| 276_Q | 309_T | 2.166 | 1.00 | |
| 59_A | 74_E | 2.165 | 1.00 | |
| 117_V | 162_L | 2.164 | 1.00 | |
| 276_Q | 307_V | 2.125 | 1.00 | |
| 134_Q | 151_A | 2.09 | 1.00 | |
| 124_Y | 155_R | 2.044 | 1.00 | |
| 121_Q | 166_Q | 2.033 | 1.00 | |
| 50_R | 204_D | 2.026 | 1.00 | |
| 138_W | 148_L | 1.957 | 1.00 | |
| 147_D | 150_N | 1.954 | 1.00 | |
| 131_Y | 135_Q | 1.915 | 1.00 | |
| 68_A | 212_D | 1.901 | 1.00 | |
| 189_E | 192_Q | 1.901 | 1.00 | |
| 152_R | 156_D | 1.888 | 1.00 | |
| 59_A | 71_V | 1.844 | 1.00 | |
| 85_M | 88_K | 1.836 | 1.00 | |
| 81_E | 202_L | 1.83 | 1.00 | |
| 255_A | 277_I | 1.824 | 1.00 | |
| 84_L | 199_E | 1.814 | 1.00 | |
| 40_V | 243_V | 1.775 | 1.00 | |
| 128_Q | 155_R | 1.774 | 1.00 | |
| 118_K | 121_Q | 1.762 | 1.00 | |
| 65_A | 214_T | 1.754 | 1.00 | |
| 261_V | 306_I | 1.754 | 1.00 | |
| 91_V | 195_L | 1.753 | 1.00 | |
| 262_L | 272_P | 1.719 | 1.00 | |
| 209_A | 235_V | 1.715 | 1.00 | |
| 80_Y | 205_S | 1.707 | 1.00 | |
| 131_Y | 155_R | 1.701 | 1.00 | |
| 64_D | 70_Q | 1.699 | 1.00 | |
| 131_Y | 148_L | 1.698 | 1.00 | |
| 262_L | 274_H | 1.696 | 1.00 | |
| 138_W | 145_A | 1.693 | 1.00 | |
| 88_K | 195_L | 1.688 | 1.00 | |
| 255_A | 325_F | 1.681 | 1.00 | |
| 111_A | 114_A | 1.674 | 1.00 | |
| 163_K | 166_Q | 1.671 | 1.00 | |
| 155_R | 159_Q | 1.649 | 1.00 | |
| 247_V | 255_A | 1.639 | 1.00 | |
| 199_E | 203_Q | 1.627 | 1.00 | |
| 124_Y | 128_Q | 1.599 | 1.00 | |
| 41_D | 244_R | 1.594 | 1.00 | |
| 102_L | 185_K | 1.594 | 1.00 | |
| 213_G | 235_V | 1.591 | 1.00 | |
| 84_L | 202_L | 1.564 | 1.00 | |
| 145_A | 149_E | 1.54 | 1.00 | |
| 242_W | 305_R | 1.531 | 1.00 | |
| 117_V | 169_L | 1.527 | 1.00 | |
| 84_L | 88_K | 1.526 | 1.00 | |
| 196_A | 199_E | 1.526 | 1.00 | |
| 114_A | 173_R | 1.524 | 1.00 | |
| 72_L | 233_F | 1.521 | 1.00 | |
| 81_E | 85_M | 1.517 | 1.00 | |
| 131_Y | 152_R | 1.506 | 1.00 | |
| 61_D | 64_D | 1.505 | 1.00 | |
| 121_Q | 125_D | 1.503 | 1.00 | |
| 126_Y | 130_F | 1.496 | 1.00 | |
| 53_G | 75_L | 1.458 | 1.00 | |
| 65_A | 238_T | 1.452 | 1.00 | |
| 243_V | 321_V | 1.449 | 1.00 | |
| 274_H | 309_T | 1.448 | 1.00 | |
| 86_Q | 194_Q | 1.446 | 1.00 | |
| 57_S | 222_P | 1.433 | 1.00 | |
| 227_N | 230_G | 1.414 | 1.00 | |
| 121_Q | 162_L | 1.404 | 0.99 | |
| 55_V | 220_V | 1.404 | 0.99 | |
| 55_V | 73_G | 1.398 | 0.99 | |
| 91_V | 95_Q | 1.378 | 0.99 | |
| 91_V | 192_Q | 1.368 | 0.99 | |
| 244_R | 303_R | 1.351 | 0.99 | |
| 102_L | 181_I | 1.348 | 0.99 | |
| 279_F | 305_R | 1.346 | 0.99 | |
| 200_L | 204_D | 1.346 | 0.99 | |
| 87_A | 191_A | 1.323 | 0.99 | |
| 92_S | 95_Q | 1.321 | 0.99 | |
| 148_L | 152_R | 1.32 | 0.99 | |
| 245_A | 323_V | 1.318 | 0.99 | |
| 277_I | 304_L | 1.317 | 0.99 | |
| 56_E | 76_D | 1.304 | 0.99 | |
| 133_R | 149_E | 1.3 | 0.99 | |
| 245_A | 306_I | 1.294 | 0.99 | |
| 132_N | 135_Q | 1.294 | 0.99 | |
| 226_L | 232_V | 1.283 | 0.99 | |
| 73_G | 207_L | 1.282 | 0.99 | |
| 98_Y | 185_K | 1.276 | 0.99 | |
| 90_G | 190_Q | 1.276 | 0.99 | |
| 156_D | 159_Q | 1.272 | 0.99 | |
| 125_D | 129_N | 1.271 | 0.99 | |
| 248_D | 251_N | 1.262 | 0.99 | |
| 159_Q | 163_K | 1.261 | 0.99 | |
| 265_T | 321_V | 1.257 | 0.99 | |
| 124_Y | 159_Q | 1.255 | 0.99 | |
| 192_Q | 196_A | 1.245 | 0.98 | |
| 216_L | 236_S | 1.244 | 0.98 | |
| 83_A | 197_Q | 1.243 | 0.98 | |
| 98_Y | 188_L | 1.237 | 0.98 | |
| 130_F | 150_N | 1.237 | 0.98 | |
| 83_A | 201_N | 1.235 | 0.98 | |
| 209_A | 212_D | 1.233 | 0.98 | |
| 129_N | 149_E | 1.226 | 0.98 | |
| 120_A | 158_A | 1.223 | 0.98 | |
| 247_V | 325_F | 1.222 | 0.98 | |
| 182_A | 185_K | 1.212 | 0.98 | |
| 56_E | 74_E | 1.208 | 0.98 | |
| 89_A | 193_A | 1.197 | 0.98 | |
| 197_Q | 201_N | 1.192 | 0.98 | |
| 135_Q | 148_L | 1.189 | 0.98 | |
| 263_L | 321_V | 1.183 | 0.98 | |
| 85_M | 196_A | 1.177 | 0.98 | |
| 119_Q | 161_T | 1.158 | 0.97 | |
| 170_R | 173_R | 1.156 | 0.97 | |
| 90_G | 187_S | 1.141 | 0.97 | |
| 83_A | 86_Q | 1.136 | 0.97 | |
| 150_N | 154_S | 1.136 | 0.97 | |
| 58_L | 222_P | 1.136 | 0.97 | |
| 117_V | 166_Q | 1.127 | 0.97 | |
| 117_V | 121_Q | 1.124 | 0.97 | |
| 100_L | 180_D | 1.12 | 0.96 | |
| 125_D | 128_Q | 1.116 | 0.96 | |
| 162_L | 166_Q | 1.115 | 0.96 | |
| 73_G | 232_V | 1.114 | 0.96 | |
| 240_P | 307_V | 1.114 | 0.96 | |
| 132_N | 136_G | 1.104 | 0.96 | |
| 77_H | 205_S | 1.102 | 0.96 | |
| 45_V | 211_S | 1.099 | 0.96 | |
| 215_L | 233_F | 1.096 | 0.96 | |
| 261_V | 275_G | 1.093 | 0.96 | |
| 97_Q | 187_S | 1.089 | 0.96 | |
| 149_E | 152_R | 1.078 | 0.95 | |
| 195_L | 199_E | 1.073 | 0.95 | |
| 99_D | 102_L | 1.066 | 0.95 | |
| 98_Y | 102_L | 1.065 | 0.95 | |
| 66_I | 72_L | 1.06 | 0.95 | |
| 61_D | 218_R | 1.053 | 0.95 | |
| 95_Q | 188_L | 1.052 | 0.95 | |
| 47_L | 233_F | 1.049 | 0.94 | |
| 263_L | 308_V | 1.047 | 0.94 | |
| 154_S | 157_Q | 1.046 | 0.94 | |
| 120_A | 165_A | 1.042 | 0.94 | |
| 262_L | 326_G | 1.037 | 0.94 | |
| 71_V | 74_E | 1.033 | 0.94 | |
| 123_A | 126_Y | 1.027 | 0.94 | |
| 124_Y | 162_L | 1.015 | 0.93 | |
| 114_A | 169_L | 1.015 | 0.93 | |
| 62_E | 217_T | 1.008 | 0.93 | |
| 284_A | 302_Y | 1.004 | 0.93 | |
| 203_Q | 208_I | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3fppA | 2 | 0.8163 | 100 | 0.392 | Contact Map | 0.757 |
| 4dk0A | 1 | 0.8464 | 100 | 0.396 | Contact Map | 0.644 |
| 2f1mA | 4 | 0.741 | 100 | 0.418 | Contact Map | 0.731 |
| 3lnnA | 2 | 0.8193 | 100 | 0.442 | Contact Map | 0.746 |
| 1vf7A | 13 | 0.759 | 100 | 0.46 | Contact Map | 0.778 |
| 4l8jA | 1 | 0.7319 | 100 | 0.476 | Contact Map | 0.784 |
| 3ne5B | 2 | 0.7319 | 100 | 0.487 | Contact Map | 0.78 |
| 4kkuA | 4 | 0.5904 | 100 | 0.56 | Contact Map | 0.806 |
| 2k32A | 1 | 0.3464 | 99.8 | 0.68 | Contact Map | 0.664 |
| 2dneA | 1 | 0.3042 | 99.5 | 0.759 | Contact Map | 0.693 |
Sequence Conservation (Image Generated using WebLogo v3)