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OPENSEQ.org

RIMJ - Ribosomal-protein-alanine acetyltransferase
UniProt: P0A948 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10851
Length: 194 (182)
Sequences: 9108
Seq/Len: 50.04

RIMJ
Paralog alert: 0.83 [within 20: 0.16] - ratio of genomes with paralogs
Cluster includes: ATDA PHNO RIMI RIMJ RIML YAFP YEDL YHHY YIAC YJAB YJGM YNCA YPEA
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
122_F 158_R 3.466 1.00
21_R 27_D 3.014 1.00
21_R 81_F 2.983 1.00
163_K 166_Y 2.673 1.00
164_E 184_A 2.661 1.00
143_A 156_L 2.602 1.00
154_D 157_A 2.503 1.00
163_K 181_V 2.283 1.00
82_D 85_E 2.258 1.00
17_R 123_E 2.216 1.00
130_R 134_R 2.142 1.00
105_C 138_I 2.083 1.00
129_I 141_I 2.017 1.00
14_T 83_P 1.979 1.00
94_F 132_M 1.969 1.00
145_Y 153_G 1.939 1.00
15_T 127_A 1.93 1.00
145_Y 156_L 1.901 1.00
15_T 123_E 1.884 1.00
139_H 169_D 1.869 1.00
29_W 56_P 1.856 1.00
157_A 163_K 1.85 1.00
23_V 79_G 1.782 1.00
147_P 179_D 1.775 1.00
79_G 88_I 1.77 1.00
169_D 188_P 1.758 1.00
166_Y 181_V 1.742 1.00
132_M 141_I 1.732 1.00
153_G 181_V 1.728 1.00
129_I 161_F 1.725 1.00
89_I 115_W 1.722 1.00
140_R 184_A 1.673 1.00
153_G 157_A 1.671 1.00
127_A 130_R 1.657 1.00
140_R 164_E 1.606 1.00
111_I 121_M 1.576 1.00
92_A 128_A 1.569 1.00
107_L 125_L 1.514 1.00
172_L 177_W 1.491 1.00
25_D 64_G 1.461 1.00
56_P 60_Q 1.451 1.00
122_F 155_L 1.444 1.00
166_Y 179_D 1.444 1.00
87_E 114_K 1.44 1.00
92_A 124_A 1.425 1.00
129_I 185_L 1.422 1.00
125_L 159_L 1.422 1.00
37_E 113_Q 1.42 1.00
153_G 163_K 1.413 1.00
55_Y 58_G 1.411 1.00
153_G 183_T 1.398 0.99
30_R 88_I 1.39 0.99
122_F 159_L 1.385 0.99
81_F 86_K 1.358 0.99
133_Q 187_T 1.321 0.99
13_L 127_A 1.305 0.99
30_R 87_E 1.287 0.99
167_A 182_L 1.287 0.99
112_G 115_W 1.282 0.99
80_L 124_A 1.277 0.99
80_L 111_I 1.214 0.98
150_K 153_G 1.213 0.98
91_V 110_S 1.211 0.98
109_Y 156_L 1.204 0.98
147_P 166_Y 1.193 0.98
163_K 183_T 1.19 0.98
109_Y 152_S 1.178 0.98
152_S 156_L 1.174 0.98
28_A 63_L 1.17 0.97
29_W 33_D 1.161 0.97
19_V 83_P 1.155 0.97
60_Q 64_G 1.152 0.97
150_K 154_D 1.146 0.97
39_R 113_Q 1.14 0.97
15_T 18_L 1.136 0.97
25_D 60_Q 1.13 0.97
139_H 177_W 1.116 0.96
116_Q 151_R 1.112 0.96
147_P 181_V 1.112 0.96
131_Y 135_T 1.108 0.96
19_V 81_F 1.091 0.96
156_L 161_F 1.09 0.96
34_Y 110_S 1.087 0.96
169_D 179_D 1.086 0.96
161_F 185_L 1.078 0.95
37_E 112_G 1.076 0.95
82_D 89_I 1.065 0.95
30_R 33_D 1.057 0.95
168_K 184_A 1.053 0.95
162_E 168_K 1.044 0.94
148_H 178_R 1.044 0.94
170_Y 180_H 1.043 0.94
28_A 56_P 1.037 0.94
61_A 65_M 1.021 0.93
126_T 159_L 1.021 0.93
121_M 155_L 1.016 0.93
129_I 159_L 1.009 0.93
13_L 20_V 1.009 0.93
62_R 66_I 1.005 0.93
131_Y 136_Q 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2vzyA40.95881000.316Contact Map0.762
3pzjA20.95881000.317Contact Map0.773
1yreA40.93811000.317Contact Map0.785
3r9fA20.93811000.318Contact Map0.769
2fckA10.9331000.32Contact Map0.801
1nslA60.94331000.324Contact Map0.89
3igrA20.94851000.328Contact Map0.783
2z10A10.922799.90.349Contact Map0.746
1s7kA10.938199.90.35Contact Map0.76
3fbuA20.86699.90.368Contact Map0.858

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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