| UniProt: | Q46890 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13106 | ||
| Length: | 212 (200) | ||
| Sequences: | 2902 | ||
| Seq/Len: | 14.51 |
| YGBL
Paralog alert: 0.64 [within 20: 0.04] - ratio of genomes with paralogs Cluster includes: ARAD FUCA RHAD SGBE ULAF YGBL |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 65_A | 69_E | 5.366 | 1.00 | |
| 103_W | 193_I | 3.25 | 1.00 | |
| 172_E | 176_E | 3.135 | 1.00 | |
| 189_K | 193_I | 2.842 | 1.00 | |
| 44_L | 84_L | 2.56 | 1.00 | |
| 117_N | 195_G | 2.507 | 1.00 | |
| 45_L | 61_L | 2.468 | 1.00 | |
| 14_E | 175_Q | 2.322 | 1.00 | |
| 43_N | 63_K | 2.197 | 1.00 | |
| 16_T | 58_P | 2.155 | 1.00 | |
| 144_K | 148_Q | 2.113 | 1.00 | |
| 13_E | 17_R | 2.105 | 1.00 | |
| 93_C | 170_C | 1.991 | 1.00 | |
| 159_A | 184_L | 1.977 | 1.00 | |
| 102_T | 189_K | 1.944 | 1.00 | |
| 134_P | 157_N | 1.914 | 1.00 | |
| 103_W | 192_F | 1.893 | 1.00 | |
| 11_L | 37_L | 1.865 | 1.00 | |
| 103_W | 189_K | 1.819 | 1.00 | |
| 106_A | 193_I | 1.808 | 1.00 | |
| 97_V | 177_A | 1.789 | 1.00 | |
| 173_S | 176_E | 1.785 | 1.00 | |
| 111_Q | 163_A | 1.775 | 1.00 | |
| 118_V | 132_N | 1.768 | 1.00 | |
| 203_T | 206_E | 1.766 | 1.00 | |
| 95_A | 174_L | 1.753 | 1.00 | |
| 85_A | 148_Q | 1.751 | 1.00 | |
| 43_N | 71_L | 1.747 | 1.00 | |
| 45_L | 63_K | 1.726 | 1.00 | |
| 37_L | 174_L | 1.703 | 1.00 | |
| 94_K | 173_S | 1.647 | 1.00 | |
| 13_E | 58_P | 1.625 | 1.00 | |
| 85_A | 89_N | 1.616 | 1.00 | |
| 57_D | 60_R | 1.598 | 1.00 | |
| 67_D | 88_R | 1.594 | 1.00 | |
| 16_T | 20_S | 1.592 | 1.00 | |
| 167_P | 184_L | 1.577 | 1.00 | |
| 39_L | 45_L | 1.505 | 1.00 | |
| 85_A | 88_R | 1.498 | 1.00 | |
| 9_Q | 13_E | 1.496 | 1.00 | |
| 21_S | 25_R | 1.462 | 1.00 | |
| 84_L | 88_R | 1.46 | 1.00 | |
| 107_L | 195_G | 1.45 | 1.00 | |
| 193_I | 196_D | 1.419 | 1.00 | |
| 89_N | 155_A | 1.412 | 1.00 | |
| 15_M | 61_L | 1.391 | 0.99 | |
| 25_R | 182_E | 1.384 | 0.99 | |
| 118_V | 135_L | 1.384 | 0.99 | |
| 137_P | 163_A | 1.383 | 0.99 | |
| 64_V | 80_V | 1.376 | 0.99 | |
| 171_G | 176_E | 1.371 | 0.99 | |
| 99_L | 181_M | 1.322 | 0.99 | |
| 119_I | 188_A | 1.32 | 0.99 | |
| 148_Q | 152_E | 1.303 | 0.99 | |
| 10_S | 14_E | 1.3 | 0.99 | |
| 60_R | 74_D | 1.292 | 0.99 | |
| 104_S | 167_P | 1.29 | 0.99 | |
| 204_A | 208_A | 1.283 | 0.99 | |
| 102_T | 106_A | 1.275 | 0.99 | |
| 169_V | 181_M | 1.275 | 0.99 | |
| 12_R | 72_S | 1.273 | 0.99 | |
| 86_L | 93_C | 1.267 | 0.99 | |
| 159_A | 169_V | 1.249 | 0.99 | |
| 37_L | 95_A | 1.235 | 0.98 | |
| 15_M | 35_L | 1.229 | 0.98 | |
| 90_N | 93_C | 1.213 | 0.98 | |
| 89_N | 151_A | 1.207 | 0.98 | |
| 101_S | 104_S | 1.202 | 0.98 | |
| 18_I | 178_A | 1.201 | 0.98 | |
| 20_S | 24_Q | 1.197 | 0.98 | |
| 137_P | 152_E | 1.18 | 0.98 | |
| 167_P | 181_M | 1.18 | 0.98 | |
| 105_T | 108_S | 1.176 | 0.98 | |
| 56_L | 60_R | 1.174 | 0.98 | |
| 98_H | 165_H | 1.173 | 0.98 | |
| 16_T | 61_L | 1.142 | 0.97 | |
| 100_H | 165_H | 1.13 | 0.97 | |
| 185_E | 189_K | 1.128 | 0.97 | |
| 82_F | 168_V | 1.126 | 0.97 | |
| 44_L | 66_A | 1.122 | 0.97 | |
| 203_T | 209_E | 1.117 | 0.96 | |
| 186_E | 189_K | 1.11 | 0.96 | |
| 152_E | 155_A | 1.11 | 0.96 | |
| 150_L | 162_L | 1.099 | 0.96 | |
| 171_G | 180_N | 1.097 | 0.96 | |
| 39_L | 63_K | 1.094 | 0.96 | |
| 22_F | 97_V | 1.092 | 0.96 | |
| 145_R | 148_Q | 1.086 | 0.96 | |
| 21_S | 24_Q | 1.083 | 0.96 | |
| 191_I | 195_G | 1.076 | 0.95 | |
| 139_Y | 149_D | 1.075 | 0.95 | |
| 102_T | 193_I | 1.074 | 0.95 | |
| 79_E | 146_I | 1.07 | 0.95 | |
| 120_R | 191_I | 1.048 | 0.94 | |
| 149_D | 152_E | 1.039 | 0.94 | |
| 192_F | 196_D | 1.034 | 0.94 | |
| 162_L | 168_V | 1.033 | 0.94 | |
| 18_I | 174_L | 1.032 | 0.94 | |
| 65_A | 71_L | 1.02 | 0.93 | |
| 110_L | 197_R | 1.014 | 0.93 | |
| 22_F | 178_A | 1.009 | 0.93 | |
| 125_Y | 130_M | 1.007 | 0.93 | |
| 47_T | 87_Y | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1e4cP | 1 | 0.9434 | 100 | 0.116 | Contact Map | 0.712 |
| 3ocrA | 2 | 0.9764 | 100 | 0.133 | Contact Map | 0.691 |
| 2opiA | 2 | 0.9481 | 100 | 0.136 | Contact Map | 0.69 |
| 2v9lA | 1 | 0.967 | 100 | 0.16 | Contact Map | 0.614 |
| 1k0wA | 6 | 0.9481 | 100 | 0.163 | Contact Map | 0.804 |
| 2z7bA | 1 | 0.9623 | 100 | 0.175 | Contact Map | 0.694 |
| 2fk5A | 2 | 0.9009 | 100 | 0.175 | Contact Map | 0.643 |
| 1pvtA | 1 | 0.9387 | 100 | 0.179 | Contact Map | 0.574 |
| 2irpA | 2 | 0.9104 | 100 | 0.193 | Contact Map | 0.719 |
| 3m4rA | 1 | 0.8632 | 100 | 0.297 | Contact Map | 0.605 |
Sequence Conservation (Image Generated using WebLogo v3)