| UniProt: | P08203 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10055 | ||
| Length: | 231 (220) | ||
| Sequences: | 2865 | ||
| Seq/Len: | 13.02 |
| ARAD
Paralog alert: 0.65 [within 20: 0.04] - ratio of genomes with paralogs Cluster includes: ARAD FUCA RHAD SGBE ULAF YGBL |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 60_S | 65_E | 5.661 | 1.00 | |
| 100_H | 199_F | 3.352 | 1.00 | |
| 178_K | 182_D | 3.179 | 1.00 | |
| 195_Y | 199_F | 2.869 | 1.00 | |
| 39_F | 81_R | 2.68 | 1.00 | |
| 40_V | 56_M | 2.596 | 1.00 | |
| 109_Q | 201_R | 2.559 | 1.00 | |
| 60_S | 63_T | 2.441 | 1.00 | |
| 38_V | 58_V | 2.389 | 1.00 | |
| 10_L | 53_A | 2.339 | 1.00 | |
| 8_Q | 181_E | 2.29 | 1.00 | |
| 7_R | 11_E | 2.179 | 1.00 | |
| 143_W | 147_N | 2.094 | 1.00 | |
| 38_V | 67_V | 2.078 | 1.00 | |
| 90_I | 176_W | 2.07 | 1.00 | |
| 99_R | 195_Y | 1.882 | 1.00 | |
| 165_G | 190_L | 1.874 | 1.00 | |
| 100_H | 195_Y | 1.865 | 1.00 | |
| 179_N | 182_D | 1.864 | 1.00 | |
| 211_Q | 214_L | 1.842 | 1.00 | |
| 100_H | 198_I | 1.84 | 1.00 | |
| 103_I | 199_F | 1.836 | 1.00 | |
| 94_V | 183_A | 1.801 | 1.00 | |
| 212_Q | 216_D | 1.801 | 1.00 | |
| 92_G | 180_A | 1.785 | 1.00 | |
| 5_L | 31_A | 1.783 | 1.00 | |
| 91_G | 179_N | 1.78 | 1.00 | |
| 63_T | 85_Q | 1.769 | 1.00 | |
| 31_A | 180_A | 1.762 | 1.00 | |
| 82_L | 147_N | 1.713 | 1.00 | |
| 52_T | 55_D | 1.694 | 1.00 | |
| 82_L | 86_A | 1.688 | 1.00 | |
| 40_V | 58_V | 1.633 | 1.00 | |
| 10_L | 14_L | 1.62 | 1.00 | |
| 173_P | 190_L | 1.614 | 1.00 | |
| 7_R | 53_A | 1.59 | 1.00 | |
| 33_D | 40_V | 1.541 | 1.00 | |
| 104_W | 201_R | 1.521 | 1.00 | |
| 127_P | 156_Q | 1.493 | 1.00 | |
| 89_S | 161_A | 1.479 | 1.00 | |
| 213_T | 217_K | 1.444 | 1.00 | |
| 98_S | 101_A | 1.428 | 1.00 | |
| 108_G | 169_H | 1.427 | 1.00 | |
| 199_F | 202_Q | 1.42 | 1.00 | |
| 82_L | 85_Q | 1.417 | 1.00 | |
| 15_A | 19_H | 1.397 | 0.99 | |
| 101_A | 173_P | 1.386 | 0.99 | |
| 175_A | 187_A | 1.37 | 0.99 | |
| 4_D | 8_Q | 1.362 | 0.99 | |
| 9_V | 29_V | 1.353 | 0.99 | |
| 14_L | 18_K | 1.351 | 0.99 | |
| 81_R | 85_Q | 1.338 | 0.99 | |
| 39_F | 61_I | 1.335 | 0.99 | |
| 95_H | 171_H | 1.329 | 0.99 | |
| 165_G | 175_A | 1.319 | 0.99 | |
| 177_G | 182_D | 1.317 | 0.99 | |
| 99_R | 103_I | 1.308 | 0.99 | |
| 147_N | 151_E | 1.286 | 0.99 | |
| 96_T | 187_A | 1.285 | 0.99 | |
| 59_V | 77_T | 1.267 | 0.99 | |
| 19_H | 188_I | 1.251 | 0.99 | |
| 173_P | 187_A | 1.247 | 0.99 | |
| 86_A | 154_E | 1.245 | 0.98 | |
| 110_S | 128_C | 1.243 | 0.98 | |
| 31_A | 92_G | 1.237 | 0.98 | |
| 151_E | 154_E | 1.233 | 0.98 | |
| 9_V | 56_M | 1.231 | 0.98 | |
| 111_I | 194_A | 1.228 | 0.98 | |
| 102_T | 105_A | 1.226 | 0.98 | |
| 107_A | 203_L | 1.224 | 0.98 | |
| 87_F | 90_I | 1.215 | 0.98 | |
| 198_I | 202_Q | 1.196 | 0.98 | |
| 110_S | 125_T | 1.177 | 0.98 | |
| 86_A | 150_V | 1.171 | 0.98 | |
| 149_I | 168_V | 1.171 | 0.98 | |
| 191_E | 195_Y | 1.17 | 0.97 | |
| 97_H | 171_H | 1.17 | 0.97 | |
| 51_M | 55_D | 1.165 | 0.97 | |
| 197_G | 201_R | 1.154 | 0.97 | |
| 16_L | 184_V | 1.141 | 0.97 | |
| 12_A | 184_V | 1.138 | 0.97 | |
| 177_G | 186_N | 1.121 | 0.97 | |
| 192_E | 195_Y | 1.119 | 0.96 | |
| 110_S | 156_Q | 1.119 | 0.96 | |
| 83_L | 90_I | 1.118 | 0.96 | |
| 99_R | 199_F | 1.116 | 0.96 | |
| 6_K | 68_E | 1.112 | 0.96 | |
| 2_L | 38_V | 1.105 | 0.96 | |
| 79_T | 174_F | 1.094 | 0.96 | |
| 198_I | 203_L | 1.086 | 0.96 | |
| 33_D | 58_V | 1.084 | 0.96 | |
| 60_S | 67_V | 1.067 | 0.95 | |
| 210_M | 214_L | 1.067 | 0.95 | |
| 16_L | 94_V | 1.053 | 0.95 | |
| 148_V | 151_E | 1.052 | 0.95 | |
| 162_Q | 219_Y | 1.043 | 0.94 | |
| 153_F | 166_V | 1.039 | 0.94 | |
| 130_R | 169_H | 1.035 | 0.94 | |
| 168_V | 174_F | 1.034 | 0.94 | |
| 112_P | 197_G | 1.033 | 0.94 | |
| 66_V | 69_G | 1.032 | 0.94 | |
| 83_L | 153_F | 1.031 | 0.94 | |
| 15_A | 18_K | 1.03 | 0.94 | |
| 55_D | 71_K | 1.017 | 0.93 | |
| 130_R | 151_E | 1.005 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1k0wA | 6 | 1 | 100 | 0.083 | Contact Map | 0.808 |
| 1e4cP | 1 | 0.9048 | 100 | 0.137 | Contact Map | 0.715 |
| 3ocrA | 2 | 0.9394 | 100 | 0.171 | Contact Map | 0.689 |
| 2opiA | 2 | 0.8874 | 100 | 0.181 | Contact Map | 0.685 |
| 2v9lA | 1 | 0.9351 | 100 | 0.197 | Contact Map | 0.628 |
| 2z7bA | 1 | 0.9351 | 100 | 0.201 | Contact Map | 0.7 |
| 1pvtA | 1 | 0.8658 | 100 | 0.204 | Contact Map | 0.563 |
| 2fk5A | 2 | 0.8312 | 100 | 0.21 | Contact Map | 0.649 |
| 2irpA | 2 | 0.8268 | 100 | 0.237 | Contact Map | 0.726 |
| 3m4rA | 1 | 0.7835 | 100 | 0.327 | Contact Map | 0.617 |
Sequence Conservation (Image Generated using WebLogo v3)