| UniProt: | P37680 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12287 | ||
| Length: | 231 (220) | ||
| Sequences: | 2864 | ||
| Seq/Len: | 13.02 |
| SGBE
Paralog alert: 0.65 [within 20: 0.04] - ratio of genomes with paralogs Cluster includes: ARAD FUCA RHAD SGBE ULAF YGBL |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 60_E | 65_K | 5.689 | 1.00 | |
| 100_H | 199_F | 3.381 | 1.00 | |
| 178_K | 182_D | 3.172 | 1.00 | |
| 195_Y | 199_F | 2.827 | 1.00 | |
| 39_M | 81_L | 2.651 | 1.00 | |
| 40_V | 56_M | 2.581 | 1.00 | |
| 109_L | 201_R | 2.51 | 1.00 | |
| 60_E | 63_S | 2.409 | 1.00 | |
| 38_W | 58_V | 2.401 | 1.00 | |
| 10_L | 53_A | 2.341 | 1.00 | |
| 8_D | 181_A | 2.296 | 1.00 | |
| 7_A | 11_A | 2.214 | 1.00 | |
| 90_I | 176_W | 2.034 | 1.00 | |
| 143_Y | 147_E | 2.033 | 1.00 | |
| 38_W | 67_V | 2 | 1.00 | |
| 165_A | 190_L | 1.881 | 1.00 | |
| 99_R | 195_Y | 1.877 | 1.00 | |
| 100_H | 195_Y | 1.862 | 1.00 | |
| 103_I | 199_F | 1.845 | 1.00 | |
| 100_H | 198_L | 1.843 | 1.00 | |
| 211_Q | 214_L | 1.839 | 1.00 | |
| 5_L | 31_A | 1.838 | 1.00 | |
| 179_N | 182_D | 1.828 | 1.00 | |
| 92_G | 180_A | 1.81 | 1.00 | |
| 94_V | 183_A | 1.79 | 1.00 | |
| 63_S | 85_R | 1.785 | 1.00 | |
| 212_N | 216_D | 1.766 | 1.00 | |
| 82_A | 147_E | 1.721 | 1.00 | |
| 31_A | 180_A | 1.716 | 1.00 | |
| 91_G | 179_N | 1.667 | 1.00 | |
| 52_T | 55_D | 1.655 | 1.00 | |
| 82_A | 86_R | 1.649 | 1.00 | |
| 173_P | 190_L | 1.613 | 1.00 | |
| 40_V | 58_V | 1.564 | 1.00 | |
| 10_L | 14_L | 1.558 | 1.00 | |
| 7_A | 53_A | 1.538 | 1.00 | |
| 104_W | 201_R | 1.512 | 1.00 | |
| 33_D | 40_V | 1.495 | 1.00 | |
| 89_E | 161_A | 1.492 | 1.00 | |
| 110_D | 128_C | 1.457 | 1.00 | |
| 213_E | 217_K | 1.453 | 1.00 | |
| 175_A | 187_A | 1.447 | 1.00 | |
| 98_S | 101_A | 1.446 | 1.00 | |
| 82_A | 85_R | 1.424 | 1.00 | |
| 15_A | 19_H | 1.412 | 1.00 | |
| 127_P | 156_R | 1.408 | 1.00 | |
| 199_F | 202_Q | 1.405 | 0.99 | |
| 177_G | 182_D | 1.403 | 0.99 | |
| 81_L | 85_R | 1.384 | 0.99 | |
| 14_L | 18_A | 1.373 | 0.99 | |
| 4_Q | 8_D | 1.368 | 0.99 | |
| 9_V | 29_V | 1.361 | 0.99 | |
| 39_M | 61_I | 1.346 | 0.99 | |
| 101_A | 173_P | 1.346 | 0.99 | |
| 108_G | 169_H | 1.344 | 0.99 | |
| 165_A | 175_A | 1.333 | 0.99 | |
| 147_E | 151_E | 1.325 | 0.99 | |
| 19_H | 188_V | 1.309 | 0.99 | |
| 151_E | 154_E | 1.301 | 0.99 | |
| 96_T | 187_A | 1.296 | 0.99 | |
| 95_H | 171_H | 1.277 | 0.99 | |
| 99_R | 103_I | 1.267 | 0.99 | |
| 86_R | 154_E | 1.262 | 0.99 | |
| 198_L | 202_Q | 1.251 | 0.99 | |
| 59_V | 77_T | 1.247 | 0.99 | |
| 97_H | 171_H | 1.236 | 0.98 | |
| 110_D | 125_A | 1.223 | 0.98 | |
| 51_M | 55_D | 1.216 | 0.98 | |
| 31_A | 92_G | 1.212 | 0.98 | |
| 9_V | 56_M | 1.208 | 0.98 | |
| 210_M | 214_L | 1.208 | 0.98 | |
| 173_P | 187_A | 1.207 | 0.98 | |
| 149_I | 168_V | 1.203 | 0.98 | |
| 107_A | 203_L | 1.191 | 0.98 | |
| 102_T | 105_S | 1.178 | 0.98 | |
| 111_L | 194_A | 1.172 | 0.98 | |
| 130_R | 151_E | 1.171 | 0.98 | |
| 162_Q | 219_Y | 1.169 | 0.97 | |
| 6_K | 68_E | 1.162 | 0.97 | |
| 191_E | 195_Y | 1.153 | 0.97 | |
| 87_Y | 90_I | 1.144 | 0.97 | |
| 86_R | 150_I | 1.133 | 0.97 | |
| 197_G | 201_R | 1.131 | 0.97 | |
| 12_A | 184_V | 1.131 | 0.97 | |
| 83_L | 90_I | 1.13 | 0.97 | |
| 33_D | 58_V | 1.125 | 0.97 | |
| 177_G | 186_N | 1.117 | 0.96 | |
| 16_L | 94_V | 1.111 | 0.96 | |
| 79_T | 174_F | 1.11 | 0.96 | |
| 110_D | 156_R | 1.107 | 0.96 | |
| 2_L | 38_W | 1.104 | 0.96 | |
| 112_P | 197_G | 1.099 | 0.96 | |
| 99_R | 199_F | 1.094 | 0.96 | |
| 192_E | 195_Y | 1.088 | 0.96 | |
| 198_L | 203_L | 1.078 | 0.95 | |
| 16_L | 184_V | 1.076 | 0.95 | |
| 60_E | 67_V | 1.07 | 0.95 | |
| 118_H | 123_Y | 1.066 | 0.95 | |
| 148_V | 151_E | 1.064 | 0.95 | |
| 168_V | 174_F | 1.043 | 0.94 | |
| 130_R | 169_H | 1.04 | 0.94 | |
| 15_A | 18_A | 1.037 | 0.94 | |
| 32_V | 91_G | 1.035 | 0.94 | |
| 153_F | 166_V | 1.026 | 0.94 | |
| 134_A | 138_N | 1.025 | 0.93 | |
| 87_Y | 176_W | 1.022 | 0.93 | |
| 83_L | 153_F | 1.019 | 0.93 | |
| 76_D | 145_T | 1.017 | 0.93 | |
| 43_P | 46_V | 1.007 | 0.93 | |
| 164_P | 186_N | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1k0wA | 6 | 1 | 100 | 0.08 | Contact Map | 0.804 |
| 1e4cP | 1 | 0.9048 | 100 | 0.135 | Contact Map | 0.717 |
| 2opiA | 2 | 0.8874 | 100 | 0.168 | Contact Map | 0.7 |
| 3ocrA | 2 | 0.9394 | 100 | 0.172 | Contact Map | 0.684 |
| 2v9lA | 1 | 0.9351 | 100 | 0.194 | Contact Map | 0.643 |
| 2z7bA | 1 | 0.9351 | 100 | 0.198 | Contact Map | 0.7 |
| 1pvtA | 1 | 0.8701 | 100 | 0.199 | Contact Map | 0.57 |
| 2fk5A | 2 | 0.8312 | 100 | 0.206 | Contact Map | 0.647 |
| 2irpA | 2 | 0.8268 | 100 | 0.227 | Contact Map | 0.724 |
| 3m4rA | 1 | 0.7835 | 100 | 0.321 | Contact Map | 0.613 |
Sequence Conservation (Image Generated using WebLogo v3)