| UniProt: | P77671 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13619 | ||
| Length: | 453 (442) | ||
| Sequences: | 8711 | ||
| Seq/Len: | 19.71 |
| ALLB
Paralog alert: 0.87 [within 20: 0.21] - ratio of genomes with paralogs Cluster includes: ALLB CODA GUAD IADA NAGA PHNM PHYDA SSNA YAHJ |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 7_I | 46_A | 4.944 | 1.00 | |
| 426_I | 431_V | 4.73 | 1.00 | |
| 379_R | 384_K | 4.417 | 1.00 | |
| 49_L | 423_T | 4.347 | 1.00 | |
| 26_K | 31_A | 4.09 | 1.00 | |
| 10_G | 46_A | 3.959 | 1.00 | |
| 424_K | 431_V | 3.832 | 1.00 | |
| 46_A | 390_F | 3.78 | 1.00 | |
| 380_I | 388_F | 3.576 | 1.00 | |
| 377_K | 385_D | 3.376 | 1.00 | |
| 356_S | 359_M | 3.345 | 1.00 | |
| 23_I | 51_V | 3.34 | 1.00 | |
| 32_A | 382_P | 3.278 | 1.00 | |
| 52_S | 391_I | 3.236 | 1.00 | |
| 51_V | 390_F | 3.177 | 1.00 | |
| 381_A | 384_K | 3.17 | 1.00 | |
| 42_E | 434_D | 3.15 | 1.00 | |
| 10_G | 51_V | 3.082 | 1.00 | |
| 359_M | 362_K | 3.048 | 1.00 | |
| 6_I | 24_A | 2.997 | 1.00 | |
| 25_V | 388_F | 2.862 | 1.00 | |
| 8_K | 43_V | 2.84 | 1.00 | |
| 5_L | 426_I | 2.77 | 1.00 | |
| 396_S | 417_T | 2.75 | 1.00 | |
| 52_S | 389_V | 2.711 | 1.00 | |
| 28_G | 385_D | 2.693 | 1.00 | |
| 54_G | 86_T | 2.663 | 1.00 | |
| 385_D | 428_R | 2.647 | 1.00 | |
| 392_Q | 423_T | 2.522 | 1.00 | |
| 29_K | 385_D | 2.5 | 1.00 | |
| 8_K | 22_D | 2.497 | 1.00 | |
| 12_V | 23_I | 2.422 | 1.00 | |
| 232_K | 258_E | 2.38 | 1.00 | |
| 425_T | 433_Y | 2.368 | 1.00 | |
| 49_L | 390_F | 2.366 | 1.00 | |
| 12_V | 21_V | 2.35 | 1.00 | |
| 9_N | 45_D | 2.323 | 1.00 | |
| 367_N | 370_D | 2.251 | 1.00 | |
| 388_F | 426_I | 2.242 | 1.00 | |
| 362_K | 366_T | 2.182 | 1.00 | |
| 23_I | 380_I | 2.163 | 1.00 | |
| 33_I | 382_P | 2.162 | 1.00 | |
| 366_T | 370_D | 2.113 | 1.00 | |
| 239_H | 263_T | 2.102 | 1.00 | |
| 294_L | 298_K | 2.068 | 1.00 | |
| 374_L | 377_K | 2.057 | 1.00 | |
| 7_I | 25_V | 2.03 | 1.00 | |
| 4_D | 26_K | 1.998 | 1.00 | |
| 51_V | 388_F | 1.964 | 1.00 | |
| 397_Y | 421_R | 1.962 | 1.00 | |
| 370_D | 379_R | 1.918 | 1.00 | |
| 361_G | 365_A | 1.911 | 1.00 | |
| 224_I | 248_G | 1.89 | 1.00 | |
| 266_S | 270_Y | 1.845 | 1.00 | |
| 52_S | 55_M | 1.838 | 1.00 | |
| 175_K | 178_E | 1.828 | 1.00 | |
| 81_A | 118_I | 1.826 | 1.00 | |
| 10_G | 390_F | 1.821 | 1.00 | |
| 46_A | 51_V | 1.804 | 1.00 | |
| 250_E | 254_R | 1.778 | 1.00 | |
| 24_A | 32_A | 1.778 | 1.00 | |
| 4_D | 24_A | 1.736 | 1.00 | |
| 81_A | 432_I | 1.718 | 1.00 | |
| 229_Y | 233_V | 1.709 | 1.00 | |
| 56_V | 369_A | 1.7 | 1.00 | |
| 21_V | 33_I | 1.683 | 1.00 | |
| 389_V | 422_I | 1.681 | 1.00 | |
| 400_T | 403_D | 1.68 | 1.00 | |
| 267_C | 270_Y | 1.66 | 1.00 | |
| 431_V | 434_D | 1.647 | 1.00 | |
| 220_E | 223_A | 1.646 | 1.00 | |
| 399_L | 418_I | 1.636 | 1.00 | |
| 25_V | 426_I | 1.627 | 1.00 | |
| 6_I | 22_D | 1.612 | 1.00 | |
| 44_M | 426_I | 1.609 | 1.00 | |
| 56_V | 368_A | 1.604 | 1.00 | |
| 5_L | 25_V | 1.604 | 1.00 | |
| 362_K | 367_N | 1.604 | 1.00 | |
| 301_W | 305_F | 1.593 | 1.00 | |
| 376_Q | 384_K | 1.592 | 1.00 | |
| 7_I | 388_F | 1.586 | 1.00 | |
| 49_L | 392_Q | 1.583 | 1.00 | |
| 366_T | 379_R | 1.578 | 1.00 | |
| 424_K | 434_D | 1.573 | 1.00 | |
| 401_N | 414_V | 1.57 | 1.00 | |
| 58_A | 372_F | 1.562 | 1.00 | |
| 3_F | 24_A | 1.553 | 1.00 | |
| 11_T | 18_A | 1.53 | 1.00 | |
| 171_K | 174_Q | 1.517 | 1.00 | |
| 18_A | 21_V | 1.502 | 1.00 | |
| 396_S | 419_G | 1.482 | 1.00 | |
| 427_L | 432_I | 1.479 | 1.00 | |
| 9_N | 20_V | 1.467 | 1.00 | |
| 28_G | 428_R | 1.46 | 1.00 | |
| 23_I | 33_I | 1.46 | 1.00 | |
| 11_T | 20_V | 1.423 | 1.00 | |
| 176_L | 183_V | 1.42 | 1.00 | |
| 58_A | 311_C | 1.414 | 1.00 | |
| 311_C | 371_I | 1.389 | 0.99 | |
| 309_I | 370_D | 1.388 | 0.99 | |
| 13_I | 361_G | 1.387 | 0.99 | |
| 302_E | 306_N | 1.386 | 0.99 | |
| 50_V | 393_P | 1.383 | 0.99 | |
| 294_L | 297_Q | 1.38 | 0.99 | |
| 390_F | 426_I | 1.379 | 0.99 | |
| 18_A | 358_P | 1.377 | 0.99 | |
| 392_Q | 395_S | 1.377 | 0.99 | |
| 299_G | 302_E | 1.371 | 0.99 | |
| 433_Y | 438_G | 1.371 | 0.99 | |
| 423_T | 435_I | 1.37 | 0.99 | |
| 106_E | 110_D | 1.367 | 0.99 | |
| 31_A | 382_P | 1.367 | 0.99 | |
| 52_S | 361_G | 1.364 | 0.99 | |
| 82_K | 433_Y | 1.361 | 0.99 | |
| 261_D | 371_I | 1.353 | 0.99 | |
| 7_I | 51_V | 1.351 | 0.99 | |
| 350_V | 360_F | 1.348 | 0.99 | |
| 231_A | 238_L | 1.333 | 0.99 | |
| 5_L | 42_E | 1.33 | 0.99 | |
| 9_N | 47_S | 1.311 | 0.99 | |
| 253_T | 306_N | 1.302 | 0.99 | |
| 254_R | 257_Q | 1.301 | 0.99 | |
| 228_L | 262_V | 1.299 | 0.99 | |
| 170_F | 174_Q | 1.298 | 0.99 | |
| 165_N | 168_Q | 1.295 | 0.99 | |
| 10_G | 388_F | 1.292 | 0.99 | |
| 256_R | 310_D | 1.29 | 0.99 | |
| 389_V | 425_T | 1.289 | 0.99 | |
| 44_M | 424_K | 1.284 | 0.99 | |
| 119_D | 428_R | 1.284 | 0.99 | |
| 370_D | 375_Q | 1.283 | 0.99 | |
| 110_D | 113_K | 1.281 | 0.99 | |
| 138_D | 181_Q | 1.274 | 0.99 | |
| 9_N | 46_A | 1.271 | 0.99 | |
| 74_E | 78_R | 1.27 | 0.99 | |
| 7_I | 426_I | 1.27 | 0.99 | |
| 22_D | 36_D | 1.269 | 0.99 | |
| 42_E | 431_V | 1.267 | 0.99 | |
| 355_M | 363_L | 1.253 | 0.99 | |
| 89_I | 372_F | 1.252 | 0.99 | |
| 62_I | 76_G | 1.249 | 0.99 | |
| 24_A | 41_K | 1.248 | 0.99 | |
| 23_I | 388_F | 1.238 | 0.98 | |
| 7_I | 390_F | 1.228 | 0.98 | |
| 246_P | 295_E | 1.222 | 0.98 | |
| 55_M | 364_M | 1.221 | 0.98 | |
| 81_A | 425_T | 1.209 | 0.98 | |
| 395_S | 423_T | 1.203 | 0.98 | |
| 107_L | 111_A | 1.201 | 0.98 | |
| 24_A | 31_A | 1.201 | 0.98 | |
| 58_A | 368_A | 1.201 | 0.98 | |
| 8_K | 45_D | 1.199 | 0.98 | |
| 390_F | 424_K | 1.195 | 0.98 | |
| 11_T | 50_V | 1.193 | 0.98 | |
| 348_E | 352_K | 1.184 | 0.98 | |
| 22_D | 34_G | 1.183 | 0.98 | |
| 62_I | 88_M | 1.17 | 0.97 | |
| 133_R | 136_E | 1.169 | 0.97 | |
| 170_F | 233_V | 1.159 | 0.97 | |
| 279_E | 306_N | 1.158 | 0.97 | |
| 184_L | 241_C | 1.156 | 0.97 | |
| 82_K | 405_E | 1.156 | 0.97 | |
| 398_V | 417_T | 1.153 | 0.97 | |
| 56_V | 377_K | 1.142 | 0.97 | |
| 11_T | 19_R | 1.14 | 0.97 | |
| 9_N | 48_G | 1.12 | 0.96 | |
| 359_M | 363_L | 1.116 | 0.96 | |
| 6_I | 43_V | 1.115 | 0.96 | |
| 55_M | 342_M | 1.113 | 0.96 | |
| 10_G | 48_G | 1.112 | 0.96 | |
| 287_C | 335_I | 1.11 | 0.96 | |
| 227_V | 238_L | 1.11 | 0.96 | |
| 303_K | 308_E | 1.109 | 0.96 | |
| 242_H | 315_D | 1.105 | 0.96 | |
| 345_M | 364_M | 1.1 | 0.96 | |
| 395_S | 421_R | 1.09 | 0.96 | |
| 44_M | 431_V | 1.081 | 0.95 | |
| 254_R | 258_E | 1.079 | 0.95 | |
| 80_A | 88_M | 1.072 | 0.95 | |
| 302_E | 305_F | 1.071 | 0.95 | |
| 135_H | 179_L | 1.067 | 0.95 | |
| 13_I | 50_V | 1.063 | 0.95 | |
| 311_C | 367_N | 1.061 | 0.95 | |
| 46_A | 424_K | 1.061 | 0.95 | |
| 364_M | 368_A | 1.059 | 0.95 | |
| 58_A | 286_K | 1.052 | 0.95 | |
| 379_R | 382_P | 1.05 | 0.94 | |
| 271_F | 300_M | 1.043 | 0.94 | |
| 56_V | 87_T | 1.043 | 0.94 | |
| 87_T | 387_D | 1.042 | 0.94 | |
| 210_D | 227_V | 1.042 | 0.94 | |
| 21_V | 380_I | 1.04 | 0.94 | |
| 85_I | 341_C | 1.038 | 0.94 | |
| 225_R | 229_Y | 1.038 | 0.94 | |
| 71_E | 76_G | 1.033 | 0.94 | |
| 276_D | 279_E | 1.022 | 0.93 | |
| 50_V | 357_L | 1.022 | 0.93 | |
| 221_V | 225_R | 1.021 | 0.93 | |
| 59_H | 242_H | 1.021 | 0.93 | |
| 245_S | 248_G | 1.017 | 0.93 | |
| 369_A | 378_G | 1.016 | 0.93 | |
| 4_D | 41_K | 1.013 | 0.93 | |
| 293_D | 296_N | 1.013 | 0.93 | |
| 40_A | 43_V | 1.01 | 0.93 | |
| 387_D | 428_R | 1.009 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2ftyA | 4 | 0.9801 | 100 | 0.202 | Contact Map | 0.805 |
| 3e74A | 4 | 0.9934 | 100 | 0.202 | Contact Map | 0.839 |
| 3dc8A | 2 | 0.9735 | 100 | 0.217 | Contact Map | 0.82 |
| 1nfgA | 4 | 0.9757 | 100 | 0.223 | Contact Map | 0.814 |
| 1gkrA | 4 | 0.9868 | 100 | 0.224 | Contact Map | 0.792 |
| 2ftwA | 1 | 0.9823 | 100 | 0.225 | Contact Map | 0.777 |
| 4bknA | 2 | 0.9823 | 100 | 0.229 | Contact Map | 0.827 |
| 2vm8A | 4 | 0.9823 | 100 | 0.229 | Contact Map | 0.861 |
| 4b90A | 2 | 0.9823 | 100 | 0.23 | Contact Map | 0.802 |
| 4gz7A | 1 | 0.9823 | 100 | 0.233 | Contact Map | 0.806 |
Sequence Conservation (Image Generated using WebLogo v3)