| UniProt: | P39377 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12567 | ||
| Length: | 390 (374) | ||
| Sequences: | 10604 | ||
| Seq/Len: | 28.35 |
| IADA
Paralog alert: 0.87 [within 20: 0.26] - ratio of genomes with paralogs Cluster includes: ALLB CODA GUAD IADA NAGA PHNM PHYDA SSNA YAHJ |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 369_Y | 374_L | 4.67 | 1.00 | |
| 347_E | 352_N | 4.589 | 1.00 | |
| 12_L | 55_L | 4.541 | 1.00 | |
| 31_A | 36_I | 4.11 | 1.00 | |
| 55_L | 358_V | 3.906 | 1.00 | |
| 15_A | 55_L | 3.858 | 1.00 | |
| 63_G | 98_T | 3.853 | 1.00 | |
| 367_Q | 374_L | 3.789 | 1.00 | |
| 58_Q | 366_E | 3.701 | 1.00 | |
| 61_C | 359_M | 3.489 | 1.00 | |
| 37_A | 350_P | 3.338 | 1.00 | |
| 345_K | 353_D | 3.277 | 1.00 | |
| 349_L | 352_N | 3.231 | 1.00 | |
| 28_V | 60_L | 3.176 | 1.00 | |
| 324_S | 327_D | 3.147 | 1.00 | |
| 15_A | 60_L | 3.04 | 1.00 | |
| 348_I | 356_L | 2.992 | 1.00 | |
| 60_L | 358_V | 2.94 | 1.00 | |
| 13_Q | 52_V | 2.813 | 1.00 | |
| 327_D | 330_R | 2.793 | 1.00 | |
| 11_L | 29_L | 2.755 | 1.00 | |
| 61_C | 357_L | 2.685 | 1.00 | |
| 30_V | 356_L | 2.67 | 1.00 | |
| 34_K | 353_D | 2.613 | 1.00 | |
| 33_G | 353_D | 2.603 | 1.00 | |
| 353_D | 371_R | 2.59 | 1.00 | |
| 14_G | 54_D | 2.581 | 1.00 | |
| 13_Q | 27_D | 2.464 | 1.00 | |
| 330_R | 334_S | 2.381 | 1.00 | |
| 51_T | 377_K | 2.38 | 1.00 | |
| 60_L | 356_L | 2.225 | 1.00 | |
| 342_L | 345_K | 2.225 | 1.00 | |
| 58_Q | 358_V | 2.187 | 1.00 | |
| 356_L | 369_Y | 2.164 | 1.00 | |
| 268_A | 272_Q | 2.162 | 1.00 | |
| 335_S | 338_G | 2.154 | 1.00 | |
| 17_L | 26_C | 2.13 | 1.00 | |
| 39_A | 42_I | 2.119 | 1.00 | |
| 12_L | 30_V | 2.063 | 1.00 | |
| 38_V | 350_P | 2.011 | 1.00 | |
| 58_Q | 360_T | 1.965 | 1.00 | |
| 368_V | 376_V | 1.964 | 1.00 | |
| 360_T | 366_E | 1.964 | 1.00 | |
| 94_E | 376_V | 1.959 | 1.00 | |
| 29_L | 37_A | 1.941 | 1.00 | |
| 28_V | 348_I | 1.912 | 1.00 | |
| 17_L | 28_V | 1.882 | 1.00 | |
| 243_E | 273_A | 1.882 | 1.00 | |
| 279_R | 338_G | 1.856 | 1.00 | |
| 334_S | 338_G | 1.826 | 1.00 | |
| 329_L | 333_T | 1.815 | 1.00 | |
| 61_C | 64_F | 1.791 | 1.00 | |
| 55_L | 60_L | 1.789 | 1.00 | |
| 374_L | 377_K | 1.745 | 1.00 | |
| 12_L | 356_L | 1.745 | 1.00 | |
| 318_V | 328_A | 1.732 | 1.00 | |
| 179_A | 183_A | 1.732 | 1.00 | |
| 97_V | 310_L | 1.712 | 1.00 | |
| 338_G | 347_E | 1.699 | 1.00 | |
| 180_N | 183_A | 1.692 | 1.00 | |
| 15_A | 358_V | 1.688 | 1.00 | |
| 93_T | 375_M | 1.681 | 1.00 | |
| 10_T | 369_Y | 1.677 | 1.00 | |
| 334_S | 347_E | 1.661 | 1.00 | |
| 217_E | 248_G | 1.645 | 1.00 | |
| 65_I | 337_A | 1.63 | 1.00 | |
| 101_V | 340_L | 1.613 | 1.00 | |
| 367_Q | 377_K | 1.612 | 1.00 | |
| 357_L | 365_I | 1.606 | 1.00 | |
| 92_L | 100_V | 1.591 | 1.00 | |
| 310_L | 332_L | 1.587 | 1.00 | |
| 65_I | 336_V | 1.565 | 1.00 | |
| 358_V | 369_Y | 1.556 | 1.00 | |
| 16_H | 23_R | 1.551 | 1.00 | |
| 269_R | 273_A | 1.548 | 1.00 | |
| 211_P | 214_D | 1.548 | 1.00 | |
| 366_E | 378_D | 1.54 | 1.00 | |
| 67_Q | 281_T | 1.533 | 1.00 | |
| 314_V | 328_A | 1.524 | 1.00 | |
| 266_G | 269_R | 1.523 | 1.00 | |
| 330_R | 335_S | 1.521 | 1.00 | |
| 33_G | 371_R | 1.521 | 1.00 | |
| 67_Q | 340_L | 1.517 | 1.00 | |
| 117_L | 121_R | 1.488 | 1.00 | |
| 344_G | 353_D | 1.475 | 1.00 | |
| 10_T | 30_V | 1.459 | 1.00 | |
| 242_L | 273_A | 1.457 | 1.00 | |
| 281_T | 339_F | 1.457 | 1.00 | |
| 67_Q | 336_V | 1.437 | 1.00 | |
| 370_A | 375_M | 1.43 | 1.00 | |
| 10_T | 51_T | 1.417 | 1.00 | |
| 14_G | 56_S | 1.412 | 1.00 | |
| 71_L | 100_V | 1.404 | 0.99 | |
| 316_V | 320_D | 1.403 | 0.99 | |
| 11_L | 27_D | 1.381 | 0.99 | |
| 26_C | 38_V | 1.363 | 0.99 | |
| 210_Q | 214_D | 1.344 | 0.99 | |
| 23_R | 26_C | 1.338 | 0.99 | |
| 16_H | 24_G | 1.33 | 0.99 | |
| 311_L | 315_Q | 1.324 | 0.99 | |
| 271_V | 327_D | 1.319 | 0.99 | |
| 16_H | 59_I | 1.301 | 0.99 | |
| 28_V | 356_L | 1.298 | 0.99 | |
| 61_C | 329_L | 1.297 | 0.99 | |
| 34_K | 344_G | 1.293 | 0.99 | |
| 26_C | 40_S | 1.293 | 0.99 | |
| 16_H | 25_I | 1.292 | 0.99 | |
| 343_T | 352_N | 1.281 | 0.99 | |
| 67_Q | 252_D | 1.279 | 0.99 | |
| 184_E | 187_V | 1.275 | 0.99 | |
| 29_L | 50_C | 1.271 | 0.99 | |
| 14_G | 55_L | 1.271 | 0.99 | |
| 376_V | 381_A | 1.271 | 0.99 | |
| 323_F | 331_P | 1.263 | 0.99 | |
| 29_L | 36_I | 1.263 | 0.99 | |
| 27_D | 42_I | 1.262 | 0.99 | |
| 314_V | 332_L | 1.262 | 0.99 | |
| 118_A | 121_R | 1.257 | 0.99 | |
| 28_V | 38_V | 1.254 | 0.99 | |
| 65_I | 99_S | 1.247 | 0.99 | |
| 35_I | 356_L | 1.242 | 0.98 | |
| 14_G | 25_I | 1.236 | 0.98 | |
| 338_G | 343_T | 1.227 | 0.98 | |
| 36_I | 350_P | 1.224 | 0.98 | |
| 30_V | 369_Y | 1.224 | 0.98 | |
| 18_Y | 329_L | 1.221 | 0.98 | |
| 281_T | 335_S | 1.219 | 0.98 | |
| 98_T | 355_D | 1.215 | 0.98 | |
| 174_D | 177_H | 1.208 | 0.98 | |
| 93_T | 368_V | 1.207 | 0.98 | |
| 53_V | 369_Y | 1.207 | 0.98 | |
| 337_A | 346_G | 1.205 | 0.98 | |
| 250_T | 279_R | 1.2 | 0.98 | |
| 15_A | 356_L | 1.199 | 0.98 | |
| 13_Q | 54_D | 1.196 | 0.98 | |
| 112_H | 115_S | 1.185 | 0.98 | |
| 65_I | 345_K | 1.182 | 0.98 | |
| 14_G | 57_G | 1.175 | 0.98 | |
| 344_G | 352_N | 1.169 | 0.97 | |
| 357_L | 368_V | 1.157 | 0.97 | |
| 175_V | 179_A | 1.154 | 0.97 | |
| 240_Q | 243_E | 1.146 | 0.97 | |
| 71_L | 88_A | 1.142 | 0.97 | |
| 182_A | 186_R | 1.138 | 0.97 | |
| 93_T | 376_V | 1.132 | 0.97 | |
| 359_M | 365_I | 1.118 | 0.96 | |
| 27_D | 39_A | 1.114 | 0.96 | |
| 12_L | 358_V | 1.111 | 0.96 | |
| 269_R | 272_Q | 1.099 | 0.96 | |
| 309_T | 312_E | 1.095 | 0.96 | |
| 243_E | 246_R | 1.092 | 0.96 | |
| 99_S | 355_D | 1.091 | 0.96 | |
| 149_E | 153_A | 1.09 | 0.96 | |
| 35_I | 348_I | 1.088 | 0.96 | |
| 90_S | 381_A | 1.087 | 0.96 | |
| 23_R | 326_S | 1.086 | 0.96 | |
| 281_T | 336_V | 1.085 | 0.96 | |
| 239_E | 269_R | 1.085 | 0.96 | |
| 208_A | 211_P | 1.085 | 0.96 | |
| 360_T | 364_R | 1.084 | 0.96 | |
| 347_E | 350_P | 1.081 | 0.95 | |
| 51_T | 374_L | 1.073 | 0.95 | |
| 270_A | 275_I | 1.07 | 0.95 | |
| 93_T | 370_A | 1.068 | 0.95 | |
| 11_L | 52_V | 1.055 | 0.95 | |
| 365_I | 368_V | 1.049 | 0.94 | |
| 26_C | 39_A | 1.046 | 0.94 | |
| 214_D | 218_N | 1.034 | 0.94 | |
| 15_A | 57_G | 1.033 | 0.94 | |
| 12_L | 369_Y | 1.029 | 0.94 | |
| 18_Y | 59_I | 1.023 | 0.93 | |
| 332_L | 336_V | 1.008 | 0.93 | |
| 327_D | 331_P | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1onwA | 2 | 1 | 100 | 0.263 | Contact Map | 0.828 |
| 4dzhA | 1 | 0.9077 | 100 | 0.408 | Contact Map | 0.752 |
| 3ls9A | 2 | 0.9026 | 100 | 0.409 | Contact Map | 0.786 |
| 2pajA | 1 | 0.9231 | 100 | 0.416 | Contact Map | 0.755 |
| 1p1mA | 1 | 0.8615 | 100 | 0.42 | Contact Map | 0.789 |
| 2ftyA | 4 | 0.941 | 100 | 0.42 | Contact Map | 0.833 |
| 4b90A | 2 | 0.9487 | 100 | 0.422 | Contact Map | 0.8 |
| 3griA | 2 | 0.8795 | 100 | 0.423 | Contact Map | 0.852 |
| 3mpgA | 2 | 0.8872 | 100 | 0.424 | Contact Map | 0.808 |
| 4f0rA | 1 | 0.9 | 100 | 0.426 | Contact Map | 0.795 |
Sequence Conservation (Image Generated using WebLogo v3)