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YBJI - Flavin mononucleotide phosphatase YbjI
UniProt: P75809 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13678
Length: 271 (264)
Sequences: 5480
Seq/Len: 20.76
YBJI
Paralog alert: 0.75 [within 20: 0.18] - ratio of genomes with paralogs
Cluster includes: COF MPGP SUPH YBHA YBJI YIDA YIGL
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
17_D 251_N 4.702 1.00
248_G 257_D 4.191 1.00
249_S 252_R 3.36 1.00
212_V 226_A 3.334 1.00
223_L 229_S 3.183 1.00
16_S 20_T 2.849 1.00
200_Q 210_V 2.764 1.00
8_V 40_F 2.759 1.00
4_K 209_E 2.739 1.00
44_S 51_L 2.703 1.00
237_S 241_A 2.665 1.00
220_I 239_V 2.514 1.00
22_N 253_E 2.34 1.00
25_R 260_D 2.328 1.00
7_A 196_L 2.289 1.00
191_H 221_E 2.282 1.00
248_G 252_R 2.276 1.00
32_Q 35_A 2.23 1.00
231_A 243_A 2.162 1.00
220_I 242_A 2.129 1.00
239_V 242_A 2.084 1.00
197_R 225_Q 2.078 1.00
27_M 57_E 2.068 1.00
5_L 41_V 2.064 1.00
206_D 209_E 2.055 1.00
207_D 225_Q 2.048 1.00
224_R 242_A 2.034 1.00
217_G 238_A 2.008 1.00
237_S 240_V 1.964 1.00
25_R 253_E 1.914 1.00
32_Q 260_D 1.902 1.00
229_S 244_K 1.889 1.00
230_F 258_V 1.87 1.00
23_R 28_A 1.828 1.00
30_Y 40_F 1.825 1.00
198_Q 201_K 1.81 1.00
212_V 223_L 1.793 1.00
217_G 236_G 1.786 1.00
197_R 201_K 1.725 1.00
32_Q 36_Q 1.701 1.00
3_I 211_V 1.687 1.00
65_V 195_G 1.677 1.00
10_M 15_L 1.658 1.00
85_S 88_A 1.645 1.00
194_N 197_R 1.627 1.00
233_E 249_S 1.625 1.00
7_A 43_A 1.608 1.00
8_V 213_F 1.582 1.00
231_A 235_A 1.534 1.00
245_Y 262_V 1.529 1.00
196_L 222_M 1.51 1.00
28_A 32_Q 1.485 1.00
208_S 227_G 1.475 1.00
228_F 245_Y 1.47 1.00
228_F 244_K 1.461 1.00
247_A 254_G 1.456 1.00
255_V 259_I 1.453 1.00
33_M 38_I 1.432 1.00
6_I 33_M 1.43 1.00
226_A 229_S 1.423 1.00
213_F 255_V 1.407 0.99
6_I 259_I 1.406 0.99
193_A 225_Q 1.404 0.99
5_L 200_Q 1.401 0.99
44_S 66_A 1.393 0.99
39_R 203_W 1.389 0.99
80_F 198_Q 1.379 0.99
3_I 38_I 1.364 0.99
31_Q 35_A 1.357 0.99
74_S 77_K 1.354 0.99
5_L 205_I 1.349 0.99
16_S 251_N 1.337 0.99
200_Q 207_D 1.332 0.99
22_N 26_F 1.318 0.99
29_Q 256_L 1.297 0.99
213_F 258_V 1.295 0.99
200_Q 205_I 1.295 0.99
138_N 141_N 1.291 0.99
223_L 239_V 1.287 0.99
91_T 172_I 1.266 0.99
238_A 241_A 1.26 0.99
3_I 228_F 1.26 0.99
247_A 258_V 1.239 0.98
220_I 224_R 1.238 0.98
245_Y 258_V 1.238 0.98
17_D 250_N 1.232 0.98
3_I 209_E 1.231 0.98
38_I 211_V 1.23 0.98
211_V 258_V 1.229 0.98
212_V 222_M 1.227 0.98
70_G 187_I 1.21 0.98
41_V 199_L 1.209 0.98
26_F 253_E 1.208 0.98
230_F 247_A 1.201 0.98
187_I 190_V 1.199 0.98
234_N 250_N 1.188 0.98
27_M 31_Q 1.179 0.98
198_Q 202_L 1.178 0.98
235_A 240_V 1.174 0.98
235_A 239_V 1.16 0.97
207_D 210_V 1.159 0.97
245_Y 261_K 1.147 0.97
211_V 230_F 1.137 0.97
248_G 254_G 1.137 0.97
82_G 198_Q 1.136 0.97
240_V 246_R 1.131 0.97
6_I 38_I 1.131 0.97
229_S 239_V 1.115 0.96
231_A 239_V 1.104 0.96
88_A 91_T 1.098 0.96
176_V 186_I 1.097 0.96
7_A 41_V 1.094 0.96
245_Y 257_D 1.083 0.96
193_A 221_E 1.081 0.95
24_E 253_E 1.081 0.95
34_K 61_E 1.068 0.95
5_L 210_V 1.06 0.95
211_V 262_V 1.06 0.95
216_G 236_G 1.057 0.95
70_G 190_V 1.056 0.95
232_M 247_A 1.055 0.95
96_L 151_L 1.044 0.94
200_Q 225_Q 1.043 0.94
258_V 262_V 1.035 0.94
82_G 187_I 1.03 0.94
174_V 221_E 1.028 0.94
88_A 172_I 1.028 0.94
78_D 81_N 1.027 0.94
26_F 29_Q 1.024 0.93
227_G 244_K 1.024 0.93
199_L 203_W 1.018 0.93
94_E 98_T 1.017 0.93
24_E 260_D 1.013 0.93
51_L 64_F 1.006 0.93
186_I 191_H 1.005 0.93
162_Q 166_H 1.002 0.92
148_K 184_D 1.002 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3pgvA40.96681000.178Contact Map0.765
1nrwA10.95571000.187Contact Map0.814
1rlmA40.99631000.189Contact Map0.849
3l7yA10.98151000.189Contact Map0.806
2b30A40.96681000.21Contact Map0.772
3daoA20.96311000.211Contact Map0.768
1rkqA20.98891000.216Contact Map0.849
1nf2A30.97421000.222Contact Map0.853
3dnpA10.98891000.227Contact Map0.815
2pq0A20.94831000.231Contact Map0.797
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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