| UniProt: | P46891 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13216 | ||
| Length: | 272 (261) | ||
| Sequences: | 5576 | ||
| Seq/Len: | 21.36 |
| COF
Paralog alert: 0.74 [within 20: 0.18] - ratio of genomes with paralogs Cluster includes: COF MPGP SUPH YBHA YBJI YIDA YIGL |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 16_P | 250_R | 4.67 | 1.00 | |
| 247_G | 256_H | 4.056 | 1.00 | |
| 209_A | 223_V | 3.348 | 1.00 | |
| 248_H | 251_N | 3.324 | 1.00 | |
| 220_L | 226_G | 3.177 | 1.00 | |
| 23_K | 259_T | 2.873 | 1.00 | |
| 3_R | 206_D | 2.85 | 1.00 | |
| 15_M | 19_H | 2.791 | 1.00 | |
| 197_T | 207_C | 2.761 | 1.00 | |
| 23_K | 252_Q | 2.692 | 1.00 | |
| 7_F | 38_L | 2.674 | 1.00 | |
| 42_T | 49_M | 2.645 | 1.00 | |
| 234_P | 238_A | 2.59 | 1.00 | |
| 21_G | 252_Q | 2.488 | 1.00 | |
| 217_R | 236_L | 2.458 | 1.00 | |
| 6_A | 193_L | 2.314 | 1.00 | |
| 188_N | 218_E | 2.237 | 1.00 | |
| 247_G | 251_N | 2.231 | 1.00 | |
| 30_R | 33_E | 2.201 | 1.00 | |
| 228_I | 240_L | 2.122 | 1.00 | |
| 22_E | 26_S | 2.121 | 1.00 | |
| 236_L | 239_E | 2.089 | 1.00 | |
| 217_R | 239_E | 2.058 | 1.00 | |
| 25_L | 55_A | 2.051 | 1.00 | |
| 204_L | 222_S | 2.045 | 1.00 | |
| 221_V | 239_E | 2.041 | 1.00 | |
| 194_T | 222_S | 2.024 | 1.00 | |
| 30_R | 259_T | 2.013 | 1.00 | |
| 4_L | 39_T | 2.008 | 1.00 | |
| 203_S | 206_D | 2.008 | 1.00 | |
| 214_M | 235_Q | 1.997 | 1.00 | |
| 227_F | 257_Y | 1.948 | 1.00 | |
| 234_P | 237_R | 1.894 | 1.00 | |
| 226_G | 241_P | 1.885 | 1.00 | |
| 195_V | 198_Q | 1.812 | 1.00 | |
| 30_R | 34_R | 1.788 | 1.00 | |
| 214_M | 233_M | 1.76 | 1.00 | |
| 28_L | 38_L | 1.743 | 1.00 | |
| 84_P | 87_V | 1.724 | 1.00 | |
| 209_A | 220_L | 1.713 | 1.00 | |
| 194_T | 198_Q | 1.677 | 1.00 | |
| 9_M | 14_L | 1.676 | 1.00 | |
| 191_A | 194_T | 1.655 | 1.00 | |
| 6_A | 41_A | 1.638 | 1.00 | |
| 63_I | 192_A | 1.607 | 1.00 | |
| 7_F | 210_F | 1.555 | 1.00 | |
| 2_A | 208_M | 1.549 | 1.00 | |
| 230_G | 248_H | 1.544 | 1.00 | |
| 228_I | 232_A | 1.524 | 1.00 | |
| 5_A | 258_L | 1.504 | 1.00 | |
| 225_S | 241_P | 1.46 | 1.00 | |
| 190_G | 222_S | 1.455 | 1.00 | |
| 205_R | 224_G | 1.448 | 1.00 | |
| 254_V | 258_L | 1.444 | 1.00 | |
| 31_L | 36_I | 1.409 | 1.00 | |
| 246_I | 253_A | 1.407 | 0.99 | |
| 21_G | 24_T | 1.407 | 0.99 | |
| 26_S | 30_R | 1.398 | 0.99 | |
| 223_V | 226_G | 1.395 | 0.99 | |
| 242_H | 261_W | 1.388 | 0.99 | |
| 197_T | 204_L | 1.378 | 0.99 | |
| 225_S | 242_H | 1.375 | 0.99 | |
| 79_H | 195_V | 1.375 | 0.99 | |
| 134_D | 137_K | 1.365 | 0.99 | |
| 37_T | 200_L | 1.354 | 0.99 | |
| 5_A | 31_L | 1.342 | 0.99 | |
| 90_L | 169_R | 1.331 | 0.99 | |
| 193_L | 219_M | 1.329 | 0.99 | |
| 246_I | 257_Y | 1.322 | 0.99 | |
| 210_F | 254_V | 1.321 | 0.99 | |
| 227_F | 246_I | 1.313 | 0.99 | |
| 29_A | 33_E | 1.306 | 0.99 | |
| 4_L | 202_L | 1.303 | 0.99 | |
| 210_F | 257_Y | 1.301 | 0.99 | |
| 15_M | 250_R | 1.288 | 0.99 | |
| 197_T | 202_L | 1.285 | 0.99 | |
| 27_T | 255_S | 1.273 | 0.99 | |
| 220_L | 236_L | 1.268 | 0.99 | |
| 24_T | 252_Q | 1.254 | 0.99 | |
| 4_L | 197_T | 1.253 | 0.99 | |
| 231_N | 249_C | 1.247 | 0.99 | |
| 2_A | 36_I | 1.24 | 0.98 | |
| 39_T | 196_L | 1.234 | 0.98 | |
| 208_M | 257_Y | 1.231 | 0.98 | |
| 72_S | 76_E | 1.229 | 0.98 | |
| 217_R | 221_V | 1.222 | 0.98 | |
| 42_T | 64_T | 1.22 | 0.98 | |
| 235_Q | 238_A | 1.21 | 0.98 | |
| 23_K | 27_T | 1.209 | 0.98 | |
| 195_V | 199_H | 1.207 | 0.98 | |
| 16_P | 249_C | 1.207 | 0.98 | |
| 208_M | 227_F | 1.206 | 0.98 | |
| 209_A | 219_M | 1.206 | 0.98 | |
| 36_I | 208_M | 1.196 | 0.98 | |
| 232_A | 237_R | 1.193 | 0.98 | |
| 32_R | 59_D | 1.185 | 0.98 | |
| 2_A | 225_S | 1.183 | 0.98 | |
| 68_T | 184_P | 1.181 | 0.98 | |
| 95_Q | 148_F | 1.18 | 0.98 | |
| 2_A | 206_D | 1.173 | 0.98 | |
| 173_C | 183_L | 1.165 | 0.97 | |
| 204_L | 207_C | 1.163 | 0.97 | |
| 184_P | 187_C | 1.163 | 0.97 | |
| 87_V | 90_L | 1.161 | 0.97 | |
| 159_Q | 163_Y | 1.154 | 0.97 | |
| 242_H | 246_I | 1.138 | 0.97 | |
| 23_K | 256_H | 1.137 | 0.97 | |
| 232_A | 236_L | 1.132 | 0.97 | |
| 208_M | 261_W | 1.124 | 0.97 | |
| 228_I | 236_L | 1.109 | 0.96 | |
| 242_H | 257_Y | 1.106 | 0.96 | |
| 171_H | 186_G | 1.105 | 0.96 | |
| 4_L | 207_C | 1.099 | 0.96 | |
| 87_V | 169_R | 1.098 | 0.96 | |
| 81_D | 195_V | 1.094 | 0.96 | |
| 171_H | 218_E | 1.091 | 0.96 | |
| 226_G | 236_L | 1.075 | 0.95 | |
| 6_A | 39_T | 1.065 | 0.95 | |
| 25_L | 29_A | 1.063 | 0.95 | |
| 213_A | 233_M | 1.055 | 0.95 | |
| 247_G | 253_A | 1.054 | 0.95 | |
| 257_Y | 261_W | 1.044 | 0.94 | |
| 6_A | 207_C | 1.04 | 0.94 | |
| 5_A | 36_I | 1.038 | 0.94 | |
| 96_W | 113_G | 1.034 | 0.94 | |
| 188_N | 191_A | 1.032 | 0.94 | |
| 190_G | 218_E | 1.016 | 0.93 | |
| 87_V | 170_A | 1.008 | 0.93 | |
| 68_T | 187_C | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3pgvA | 4 | 0.9706 | 100 | 0.225 | Contact Map | 0.784 |
| 1nrwA | 1 | 0.9485 | 100 | 0.262 | Contact Map | 0.807 |
| 2b30A | 4 | 0.9669 | 100 | 0.269 | Contact Map | 0.769 |
| 3l7yA | 1 | 0.9669 | 100 | 0.281 | Contact Map | 0.783 |
| 1nf2A | 3 | 0.9743 | 100 | 0.284 | Contact Map | 0.856 |
| 3daoA | 2 | 0.9522 | 100 | 0.286 | Contact Map | 0.761 |
| 1rkqA | 2 | 0.9926 | 100 | 0.289 | Contact Map | 0.821 |
| 2rbkA | 1 | 0.9375 | 100 | 0.293 | Contact Map | 0.75 |
| 1rlmA | 4 | 0.9779 | 100 | 0.303 | Contact Map | 0.847 |
| 3dnpA | 1 | 0.9853 | 100 | 0.305 | Contact Map | 0.811 |
Sequence Conservation (Image Generated using WebLogo v3)