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OPENSEQ.org

YIDA - Sugar phosphatase YidA
UniProt: P0A8Y5 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11195
Length: 270 (268)
Sequences: 5652
Seq/Len: 21.09

YIDA
Paralog alert: 0.74 [within 20: 0.18] - ratio of genomes with paralogs
Cluster includes: COF MPGP SUPH YBHA YBJI YIDA YIGL
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
17_P 256_L 4.654 1.00
253_K 262_F 4.122 1.00
217_A 231_A 3.379 1.00
254_S 257_E 3.346 1.00
228_I 234_G 3.208 1.00
4_K 214_E 2.878 1.00
24_A 265_E 2.878 1.00
16_L 20_T 2.815 1.00
205_A 215_I 2.794 1.00
24_A 258_D 2.725 1.00
8_I 39_V 2.674 1.00
43_T 50_V 2.665 1.00
242_P 246_E 2.61 1.00
22_S 258_D 2.514 1.00
225_I 244_V 2.488 1.00
7_A 201_V 2.364 1.00
253_K 257_E 2.302 1.00
31_A 34_A 2.302 1.00
196_N 226_A 2.258 1.00
244_V 247_V 2.155 1.00
236_A 248_A 2.14 1.00
225_I 247_V 2.1 1.00
5_L 40_V 2.087 1.00
23_P 27_N 2.068 1.00
26_K 56_E 2.061 1.00
211_K 214_E 2.059 1.00
212_P 230_Y 2.044 1.00
202_K 230_Y 2.034 1.00
235_V 263_A 2.016 1.00
222_E 243_S 2.007 1.00
229_E 247_V 1.971 1.00
31_A 265_E 1.929 1.00
242_P 245_K 1.887 1.00
29_I 39_V 1.83 1.00
222_E 241_I 1.804 1.00
203_S 206_D 1.803 1.00
234_G 249_N 1.785 1.00
217_A 228_I 1.768 1.00
31_A 35_R 1.737 1.00
89_S 92_D 1.735 1.00
202_K 206_D 1.7 1.00
199_T 202_K 1.676 1.00
67_I 200_G 1.671 1.00
10_M 15_L 1.658 1.00
3_I 216_M 1.651 1.00
7_A 42_T 1.609 1.00
8_I 218_I 1.606 1.00
238_D 254_S 1.562 1.00
236_A 240_A 1.543 1.00
233_V 249_N 1.528 1.00
250_F 267_Y 1.521 1.00
76_K 79_D 1.5 1.00
27_N 31_A 1.484 1.00
84_A 203_S 1.483 1.00
213_E 232_G 1.471 1.00
233_V 250_F 1.468 1.00
6_I 264_I 1.447 1.00
198_G 230_Y 1.44 1.00
252_T 259_G 1.426 1.00
6_I 32_A 1.421 1.00
205_A 212_P 1.417 1.00
22_S 25_V 1.407 0.99
38_N 208_L 1.402 0.99
260_V 264_I 1.398 0.99
231_A 234_G 1.394 0.99
32_A 37_V 1.378 0.99
205_A 210_I 1.377 0.99
16_L 256_L 1.374 0.99
218_I 260_V 1.369 0.99
217_A 227_M 1.36 0.99
201_V 227_M 1.353 0.99
5_L 210_I 1.337 0.99
3_I 233_V 1.334 0.99
141_E 144_K 1.316 0.99
3_I 37_V 1.316 0.99
43_T 68_T 1.291 0.99
30_A 34_A 1.282 0.99
240_A 245_K 1.282 0.99
216_M 263_A 1.281 0.99
218_I 263_A 1.276 0.99
5_L 205_A 1.276 0.99
28_A 261_A 1.27 0.99
76_K 81_S 1.269 0.99
252_T 263_A 1.266 0.99
3_I 214_E 1.263 0.99
203_S 207_V 1.256 0.99
216_M 235_V 1.247 0.99
228_I 244_V 1.246 0.98
235_V 252_T 1.245 0.98
243_S 246_E 1.239 0.98
95_F 177_K 1.238 0.98
17_P 255_N 1.23 0.98
25_V 258_D 1.22 0.98
24_A 28_A 1.216 0.98
40_V 204_L 1.214 0.98
240_A 244_V 1.208 0.98
239_N 255_N 1.208 0.98
225_I 229_E 1.195 0.98
250_F 263_A 1.189 0.98
72_A 192_D 1.187 0.98
250_F 266_K 1.174 0.98
5_L 215_I 1.174 0.98
37_V 216_M 1.165 0.97
253_K 259_G 1.153 0.97
92_D 95_F 1.147 0.97
179_T 226_A 1.147 0.97
212_P 215_I 1.145 0.97
216_M 267_Y 1.145 0.97
192_D 195_V 1.133 0.97
24_A 262_F 1.133 0.97
236_A 244_V 1.132 0.97
179_T 194_R 1.127 0.97
26_K 30_A 1.12 0.96
100_S 156_M 1.12 0.96
245_K 251_V 1.115 0.96
86_T 203_S 1.107 0.96
7_A 215_I 1.093 0.96
198_G 226_A 1.091 0.96
181_L 191_L 1.09 0.96
167_I 171_P 1.088 0.96
234_G 244_V 1.078 0.95
250_F 262_F 1.051 0.94
92_D 177_K 1.049 0.94
237_M 252_T 1.048 0.94
7_A 40_V 1.044 0.94
162_I 165_Q 1.042 0.94
221_Q 241_I 1.038 0.94
6_I 37_V 1.037 0.94
86_T 192_D 1.023 0.93
65_Y 208_L 1.02 0.93
215_I 231_A 1.019 0.93
196_N 199_T 1.016 0.93
33_R 60_E 1.013 0.93
205_A 230_Y 1.012 0.93
263_A 267_Y 1.012 0.93
72_A 195_V 1.01 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3pgvA40.97411000.169Contact Map0.776
1rkqA211000.17Contact Map0.832
2b30A40.98891000.185Contact Map0.763
1nrwA10.96671000.188Contact Map0.806
3l7yA10.97411000.193Contact Map0.785
3mpoA40.99631000.204Contact Map0.857
1nf2A30.97411000.21Contact Map0.862
1rlmA40.97041000.212Contact Map0.847
3daoA20.96671000.217Contact Map0.76
3dnpA10.98151000.225Contact Map0.808

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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