| UniProt: | P41407 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12695 | ||
| Length: | 201 (199) | ||
| Sequences: | 3270 | ||
| Seq/Len: | 16.43 |
| AZOR
Paralog alert: 0.64 [within 20: 0.03] - ratio of genomes with paralogs Cluster includes: AZOR KEFF KEFG MDAB NQOR YCAK |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 39_T | 83_E | 3.961 | 1.00 | |
| 3_K | 37_E | 3.772 | 1.00 | |
| 39_T | 86_A | 2.9 | 1.00 | |
| 42_D | 45_A | 2.719 | 1.00 | |
| 41_R | 83_E | 2.69 | 1.00 | |
| 82_A | 86_A | 2.545 | 1.00 | |
| 50_V | 103_T | 2.417 | 1.00 | |
| 135_A | 161_L | 2.304 | 1.00 | |
| 24_Y | 27_E | 2.245 | 1.00 | |
| 24_Y | 192_K | 2.228 | 1.00 | |
| 106_K | 110_D | 2.179 | 1.00 | |
| 120_R | 127_E | 2.108 | 1.00 | |
| 25_F | 138_I | 2.096 | 1.00 | |
| 26_V | 30_R | 2.02 | 1.00 | |
| 23_D | 27_E | 2.006 | 1.00 | |
| 6_V | 26_V | 1.963 | 1.00 | |
| 3_K | 86_A | 1.931 | 1.00 | |
| 85_K | 117_V | 1.904 | 1.00 | |
| 50_V | 107_N | 1.886 | 1.00 | |
| 39_T | 87_H | 1.849 | 1.00 | |
| 4_V | 36_D | 1.823 | 1.00 | |
| 54_E | 57_G | 1.763 | 1.00 | |
| 78_D | 82_A | 1.73 | 1.00 | |
| 135_A | 166_I | 1.671 | 1.00 | |
| 82_A | 85_K | 1.635 | 1.00 | |
| 101_I | 156_Y | 1.627 | 1.00 | |
| 46_N | 79_E | 1.625 | 1.00 | |
| 18_S | 140_S | 1.621 | 1.00 | |
| 77_S | 81_I | 1.614 | 1.00 | |
| 53_G | 56_V | 1.602 | 1.00 | |
| 28_Q | 31_E | 1.597 | 1.00 | |
| 27_E | 31_E | 1.584 | 1.00 | |
| 23_D | 40_V | 1.56 | 1.00 | |
| 134_K | 167_T | 1.556 | 1.00 | |
| 103_T | 107_N | 1.55 | 1.00 | |
| 89_V | 136_I | 1.53 | 1.00 | |
| 90_I | 135_A | 1.507 | 1.00 | |
| 181_P | 185_A | 1.502 | 1.00 | |
| 87_H | 90_I | 1.479 | 1.00 | |
| 27_E | 30_R | 1.452 | 1.00 | |
| 94_A | 102_S | 1.415 | 1.00 | |
| 84_L | 90_I | 1.409 | 1.00 | |
| 28_Q | 32_K | 1.405 | 0.99 | |
| 8_K | 22_S | 1.401 | 0.99 | |
| 107_N | 111_L | 1.388 | 0.99 | |
| 193_A | 197_S | 1.387 | 0.99 | |
| 22_S | 93_A | 1.383 | 0.99 | |
| 193_A | 196_D | 1.378 | 0.99 | |
| 189_S | 193_A | 1.372 | 0.99 | |
| 8_K | 40_V | 1.361 | 0.99 | |
| 90_I | 166_I | 1.355 | 0.99 | |
| 6_V | 22_S | 1.354 | 0.99 | |
| 189_S | 192_K | 1.339 | 0.99 | |
| 81_I | 117_V | 1.334 | 0.99 | |
| 28_Q | 196_D | 1.32 | 0.99 | |
| 109_F | 160_F | 1.312 | 0.99 | |
| 4_V | 89_V | 1.308 | 0.99 | |
| 137_V | 171_F | 1.29 | 0.99 | |
| 99_F | 163_F | 1.278 | 0.99 | |
| 18_S | 93_A | 1.261 | 0.99 | |
| 92_I | 105_L | 1.26 | 0.99 | |
| 28_Q | 195_I | 1.259 | 0.99 | |
| 89_V | 134_K | 1.256 | 0.99 | |
| 25_F | 29_W | 1.254 | 0.99 | |
| 185_A | 189_S | 1.243 | 0.98 | |
| 187_A | 190_D | 1.243 | 0.98 | |
| 3_K | 39_T | 1.238 | 0.98 | |
| 27_E | 192_K | 1.221 | 0.98 | |
| 180_G | 183_M | 1.22 | 0.98 | |
| 51_L | 54_E | 1.206 | 0.98 | |
| 8_K | 19_N | 1.2 | 0.98 | |
| 9_S | 104_Q | 1.192 | 0.98 | |
| 68_P | 71_Q | 1.181 | 0.98 | |
| 80_L | 108_Y | 1.163 | 0.97 | |
| 53_G | 57_G | 1.162 | 0.97 | |
| 79_E | 83_E | 1.158 | 0.97 | |
| 81_I | 118_T | 1.149 | 0.97 | |
| 88_D | 133_K | 1.145 | 0.97 | |
| 186_K | 190_D | 1.131 | 0.97 | |
| 76_L | 79_E | 1.13 | 0.97 | |
| 192_K | 196_D | 1.124 | 0.97 | |
| 30_R | 37_E | 1.1 | 0.96 | |
| 138_I | 172_V | 1.094 | 0.96 | |
| 141_R | 175_E | 1.085 | 0.96 | |
| 113_A | 164_I | 1.079 | 0.95 | |
| 19_N | 42_D | 1.073 | 0.95 | |
| 29_W | 36_D | 1.071 | 0.95 | |
| 78_D | 114_R | 1.057 | 0.95 | |
| 67_T | 70_Q | 1.052 | 0.95 | |
| 41_R | 108_Y | 1.048 | 0.94 | |
| 11_I | 97_Y | 1.042 | 0.94 | |
| 82_A | 117_V | 1.04 | 0.94 | |
| 151_D | 155_P | 1.039 | 0.94 | |
| 9_S | 105_L | 1.036 | 0.94 | |
| 96_M | 153_V | 1.033 | 0.94 | |
| 24_Y | 188_Q | 1.024 | 0.93 | |
| 25_F | 91_V | 1.024 | 0.93 | |
| 54_E | 69_R | 1.021 | 0.93 | |
| 6_V | 40_V | 1.016 | 0.93 | |
| 41_R | 46_N | 1.013 | 0.93 | |
| 28_Q | 192_K | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1t5bA | 2 | 0.995 | 100 | 0.239 | Contact Map | 0.756 |
| 2hpvA | 4 | 0.9851 | 100 | 0.262 | Contact Map | 0.742 |
| 4c0xA | 1 | 0.9851 | 100 | 0.265 | Contact Map | 0.68 |
| 3r6wA | 2 | 0.995 | 100 | 0.268 | Contact Map | 0.673 |
| 3p0rA | 1 | 0.99 | 100 | 0.272 | Contact Map | 0.69 |
| 1d4aA | 4 | 0.9701 | 100 | 0.283 | Contact Map | 0.744 |
| 3u7iA | 4 | 0.9801 | 100 | 0.285 | Contact Map | 0.749 |
| 3lcmA | 4 | 0.9353 | 100 | 0.3 | Contact Map | 0.841 |
| 4gi5A | 2 | 0.9701 | 100 | 0.301 | Contact Map | 0.755 |
| 4fglA | 4 | 0.9502 | 100 | 0.321 | Contact Map | 0.75 |
Sequence Conservation (Image Generated using WebLogo v3)