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OPENSEQ.org

NQOR - NAD(P)H dehydrogenase (quinone)
UniProt: P0A8G6 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11540
Length: 198 (197)
Sequences: 2086
Seq/Len: 10.59

NQOR
Paralog alert: 0.30 [within 20: 0.03] - ratio of genomes with paralogs
Cluster includes: AZOR KEFF KEFG MDAB NQOR YCAK
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
35_V 65_E 3.538 1.00
18_M 182_A 2.624 1.00
187_E 191_G 2.494 1.00
29_V 187_E 2.491 1.00
21_A 24_E 2.47 1.00
21_A 183_R 2.424 1.00
109_S 185_Q 2.283 1.00
176_Q 180_S 2.255 1.00
9_Y 84_S 2.188 1.00
25_G 186_G 2.175 1.00
88_R 92_D 2.153 1.00
26_A 34_V 2.113 1.00
73_I 189_V 2.085 1.00
6_V 23_A 2.065 1.00
76_T 84_S 1.989 1.00
45_P 49_E 1.979 1.00
110_V 127_T 1.97 1.00
24_E 183_R 1.946 1.00
3_K 33_E 1.878 1.00
15_I 75_G 1.812 1.00
20_R 36_V 1.808 1.00
24_E 28_K 1.764 1.00
64_Q 68_D 1.76 1.00
94_T 134_H 1.753 1.00
23_A 28_K 1.726 1.00
4_V 71_A 1.708 1.00
21_A 179_L 1.693 1.00
122_Q 125_T 1.692 1.00
112_S 163_T 1.688 1.00
16_E 20_R 1.683 1.00
85_G 89_T 1.675 1.00
186_G 190_A 1.667 1.00
5_L 69_Y 1.642 1.00
82_N 126_S 1.518 1.00
182_A 186_G 1.511 1.00
88_R 130_T 1.507 1.00
150_D 177_E 1.495 1.00
73_I 109_S 1.467 1.00
30_D 194_V 1.445 1.00
17_T 20_R 1.423 1.00
125_T 129_T 1.419 1.00
22_V 111_F 1.412 1.00
67_A 102_A 1.406 0.99
76_T 127_T 1.385 0.99
107_L 196_L 1.379 0.99
97_L 102_A 1.366 0.99
108_A 136_M 1.362 0.99
108_A 131_L 1.347 0.99
76_T 83_M 1.345 0.99
74_F 127_T 1.336 0.99
48_F 53_G 1.336 0.99
83_M 88_R 1.329 0.99
158_T 163_T 1.328 0.99
180_S 183_R 1.313 0.99
132_A 140_P 1.3 0.99
104_Y 144_A 1.289 0.99
147_E 180_S 1.286 0.99
71_A 189_V 1.285 0.99
83_M 126_S 1.283 0.99
67_A 97_L 1.271 0.99
22_V 186_G 1.26 0.99
37_K 65_E 1.257 0.99
3_K 68_D 1.251 0.99
42_T 89_T 1.248 0.99
191_G 195_K 1.241 0.98
155_R 177_E 1.235 0.98
35_V 69_Y 1.233 0.98
8_Y 16_E 1.232 0.98
45_P 48_F 1.228 0.98
78_T 123_T 1.215 0.98
22_V 73_I 1.215 0.98
64_Q 67_A 1.214 0.98
139_V 192_L 1.204 0.98
71_A 107_L 1.203 0.98
72_I 136_M 1.193 0.98
75_G 111_F 1.19 0.98
20_R 28_K 1.179 0.98
14_H 170_G 1.167 0.97
109_S 189_V 1.155 0.97
17_T 179_L 1.153 0.97
132_A 138_I 1.144 0.97
22_V 75_G 1.135 0.97
107_L 189_V 1.117 0.96
19_A 23_A 1.112 0.96
175_S 178_E 1.111 0.96
192_L 196_L 1.108 0.96
74_F 87_M 1.094 0.96
146_Q 149_F 1.084 0.96
29_V 183_R 1.083 0.96
23_A 34_V 1.078 0.95
101_G 104_Y 1.067 0.95
48_F 52_G 1.064 0.95
44_P 89_T 1.062 0.95
45_P 52_G 1.055 0.95
193_A 197_N 1.054 0.95
66_L 90_F 1.048 0.94
5_L 37_K 1.035 0.94
141_I 181_I 1.029 0.94
6_V 19_A 1.023 0.93
5_L 65_E 1.022 0.93
23_A 36_V 1.022 0.93
76_T 112_S 1.018 0.93
82_N 88_R 1.017 0.93
189_V 193_A 1.017 0.93
86_Q 92_D 1.01 0.93
16_E 38_R 1.002 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1ydgA80.95451000.379Contact Map0.822
4dy4A20.97981000.38Contact Map0.762
3zhoA20.97981000.387Contact Map0.761
2a5lA20.97471000.391Contact Map0.796
2zkiA80.95961000.405Contact Map0.819
1rliA40.83331000.426Contact Map0.723
1sqsA20.85351000.436Contact Map0.737
3d7nA10.8991000.445Contact Map0.682
2hpvA40.85351000.458Contact Map0.619
3p0rA10.85351000.466Contact Map0.604

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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