| UniProt: | P37765 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12433 | ||
| Length: | 291 (246) | ||
| Sequences: | 3005 | ||
| Seq/Len: | 12.22 |
| RLUB
Paralog alert: 0.66 [within 20: 0.01] - ratio of genomes with paralogs Cluster includes: RLUA RLUB RLUC RLUD RLUE RLUF RSUA TRUC |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 32_D | 48_L | 6.134 | 1.00 | |
| 28_R | 53_D | 5.549 | 1.00 | |
| 30_S | 51_R | 4.21 | 1.00 | |
| 139_E | 214_R | 2.986 | 1.00 | |
| 72_Y | 94_R | 2.721 | 1.00 | |
| 194_R | 197_R | 2.52 | 1.00 | |
| 15_G | 20_I | 2.49 | 1.00 | |
| 162_L | 198_R | 2.329 | 1.00 | |
| 154_R | 158_R | 2.294 | 1.00 | |
| 22_S | 26_A | 2.256 | 1.00 | |
| 195_E | 199_L | 2.236 | 1.00 | |
| 114_C | 209_R | 2.228 | 1.00 | |
| 6_Q | 21_E | 2.218 | 1.00 | |
| 70_L | 231_E | 2.184 | 1.00 | |
| 23_I | 52_I | 2.143 | 1.00 | |
| 230_T | 236_Q | 2.127 | 1.00 | |
| 114_C | 211_I | 2.123 | 1.00 | |
| 225_P | 228_G | 2.086 | 1.00 | |
| 152_K | 205_V | 2.085 | 1.00 | |
| 70_L | 229_W | 2.026 | 1.00 | |
| 104_I | 126_A | 1.989 | 1.00 | |
| 78_E | 94_R | 1.967 | 1.00 | |
| 8_V | 50_I | 1.958 | 1.00 | |
| 170_K | 185_N | 1.954 | 1.00 | |
| 141_A | 185_N | 1.943 | 1.00 | |
| 143_R | 183_W | 1.935 | 1.00 | |
| 9_L | 20_I | 1.919 | 1.00 | |
| 139_E | 185_N | 1.909 | 1.00 | |
| 234_L | 238_N | 1.877 | 1.00 | |
| 49_K | 56_L | 1.839 | 1.00 | |
| 9_L | 57_I | 1.833 | 1.00 | |
| 30_S | 35_I | 1.814 | 1.00 | |
| 8_V | 42_V | 1.806 | 1.00 | |
| 51_R | 56_L | 1.803 | 1.00 | |
| 137_E | 187_T | 1.789 | 1.00 | |
| 114_C | 226_R | 1.778 | 1.00 | |
| 91_V | 117_L | 1.769 | 1.00 | |
| 184_Y | 200_W | 1.75 | 1.00 | |
| 153_L | 157_S | 1.733 | 1.00 | |
| 82_R | 92_F | 1.67 | 1.00 | |
| 71_A | 218_I | 1.668 | 1.00 | |
| 139_E | 187_T | 1.648 | 1.00 | |
| 137_E | 214_R | 1.64 | 1.00 | |
| 156_L | 203_V | 1.625 | 1.00 | |
| 141_A | 183_W | 1.6 | 1.00 | |
| 19_E | 22_S | 1.591 | 1.00 | |
| 29_V | 52_I | 1.568 | 1.00 | |
| 154_R | 157_S | 1.558 | 1.00 | |
| 37_K | 40_D | 1.548 | 1.00 | |
| 145_F | 206_Q | 1.522 | 1.00 | |
| 82_R | 105_A | 1.502 | 1.00 | |
| 30_S | 54_G | 1.498 | 1.00 | |
| 76_E | 114_C | 1.46 | 1.00 | |
| 22_S | 25_E | 1.449 | 1.00 | |
| 113_T | 196_V | 1.439 | 1.00 | |
| 167_A | 170_K | 1.424 | 1.00 | |
| 69_V | 122_D | 1.421 | 1.00 | |
| 129_L | 215_Y | 1.4 | 0.99 | |
| 169_F | 172_I | 1.4 | 0.99 | |
| 36_A | 40_D | 1.39 | 0.99 | |
| 71_A | 116_L | 1.379 | 0.99 | |
| 126_A | 130_M | 1.375 | 0.99 | |
| 233_D | 236_Q | 1.324 | 0.99 | |
| 137_E | 189_T | 1.323 | 0.99 | |
| 24_I | 29_V | 1.322 | 0.99 | |
| 149_D | 152_K | 1.319 | 0.99 | |
| 80_C | 92_F | 1.314 | 0.99 | |
| 80_C | 105_A | 1.305 | 0.99 | |
| 113_T | 142_V | 1.297 | 0.99 | |
| 143_R | 209_R | 1.295 | 0.99 | |
| 144_V | 205_V | 1.29 | 0.99 | |
| 130_M | 215_Y | 1.289 | 0.99 | |
| 88_R | 111_V | 1.276 | 0.99 | |
| 144_V | 200_W | 1.273 | 0.99 | |
| 9_L | 15_G | 1.262 | 0.99 | |
| 142_V | 184_Y | 1.26 | 0.99 | |
| 156_L | 200_W | 1.256 | 0.99 | |
| 113_T | 197_R | 1.249 | 0.99 | |
| 173_K | 185_N | 1.225 | 0.98 | |
| 68_R | 231_E | 1.223 | 0.98 | |
| 4_K | 41_R | 1.222 | 0.98 | |
| 150_D | 154_R | 1.219 | 0.98 | |
| 161_Q | 202_A | 1.21 | 0.98 | |
| 127_N | 130_M | 1.207 | 0.98 | |
| 217_D | 239_Y | 1.207 | 0.98 | |
| 146_G | 205_V | 1.205 | 0.98 | |
| 128_R | 134_R | 1.197 | 0.98 | |
| 125_L | 215_Y | 1.191 | 0.98 | |
| 112_N | 197_R | 1.188 | 0.98 | |
| 127_N | 131_H | 1.187 | 0.98 | |
| 152_K | 203_V | 1.183 | 0.98 | |
| 69_V | 232_L | 1.166 | 0.97 | |
| 164_D | 198_R | 1.149 | 0.97 | |
| 116_L | 220_L | 1.141 | 0.97 | |
| 84_D | 88_R | 1.134 | 0.97 | |
| 103_W | 119_F | 1.129 | 0.97 | |
| 186_V | 200_W | 1.127 | 0.97 | |
| 69_V | 125_L | 1.127 | 0.97 | |
| 214_R | 219_P | 1.126 | 0.97 | |
| 120_T | 126_A | 1.125 | 0.97 | |
| 5_L | 24_I | 1.112 | 0.96 | |
| 188_L | 195_E | 1.11 | 0.96 | |
| 141_A | 213_V | 1.109 | 0.96 | |
| 230_T | 233_D | 1.106 | 0.96 | |
| 148_V | 184_Y | 1.098 | 0.96 | |
| 156_L | 199_L | 1.087 | 0.96 | |
| 162_L | 165_G | 1.086 | 0.96 | |
| 81_T | 90_T | 1.084 | 0.96 | |
| 201_E | 206_Q | 1.077 | 0.95 | |
| 25_E | 38_L | 1.073 | 0.95 | |
| 144_V | 184_Y | 1.068 | 0.95 | |
| 77_G | 111_V | 1.066 | 0.95 | |
| 156_L | 169_F | 1.05 | 0.94 | |
| 124_E | 128_R | 1.044 | 0.94 | |
| 160_V | 203_V | 1.044 | 0.94 | |
| 198_R | 201_E | 1.042 | 0.94 | |
| 72_Y | 95_L | 1.025 | 0.93 | |
| 155_D | 203_V | 1.019 | 0.93 | |
| 166_P | 169_F | 1.013 | 0.93 | |
| 232_L | 236_Q | 1.012 | 0.93 | |
| 186_V | 196_V | 1.007 | 0.93 | |
| 3_E | 11_R | 1.006 | 0.93 | |
| 15_G | 23_I | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3dh3A | 4 | 0.9381 | 100 | 0.317 | Contact Map | 0.864 |
| 4lgtA | 2 | 0.8522 | 100 | 0.322 | Contact Map | 0.833 |
| 1vioA | 2 | 0.8247 | 100 | 0.355 | Contact Map | 0.843 |
| 1kskA | 1 | 0.7904 | 100 | 0.368 | Contact Map | 0.739 |
| 2gmlA | 2 | 0.7698 | 100 | 0.443 | Contact Map | 0.786 |
| 2olwA | 2 | 0.6804 | 100 | 0.506 | Contact Map | 0.859 |
| 2omlA | 1 | 0.5979 | 100 | 0.507 | Contact Map | 0.83 |
| 1v9fA | 1 | 0.9588 | 100 | 0.511 | Contact Map | 0.526 |
| 2i82A | 4 | 0.6804 | 100 | 0.63 | Contact Map | 0.536 |
| 1v9kA | 2 | 0.701 | 100 | 0.65 | Contact Map | 0.514 |
Sequence Conservation (Image Generated using WebLogo v3)