| UniProt: | P33593 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12078 | ||
| Length: | 254 (236) | ||
| Sequences: | 71240 | ||
| Seq/Len: | 301.86 |
| NIKD
Paralog alert: 0.95 [within 20: 0.89] - ratio of genomes with paralogs Cluster includes: ARTP BTUD CCMA CYSA DDPD DDPF DPPD DPPF FBPC FECE FEPC FHUC FTSE GLNQ GLTL HISP LIVF LIVG LOLD LPTB MALK METN MLAF MODC NIKD NIKE OPPD OPPF PHNC PHNK PHNL POTA POTG PROV PSTB SAPD SAPF SSUB SUFC TAUB THIQ UGPC YADG YBBA YBBL YCJV YDCT YECC YEHX YHDZ YNJD ZNUC |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 30_R | 210_D | 3.304 | 1.00 | |
| 33_A | 208_A | 3.23 | 1.00 | |
| 6_E | 25_T | 3.201 | 1.00 | |
| 9_N | 21_G | 3.076 | 1.00 | |
| 8_R | 63_E | 3.012 | 1.00 | |
| 80_K | 160_P | 2.962 | 1.00 | |
| 133_V | 136_L | 2.917 | 1.00 | |
| 63_E | 70_P | 2.878 | 1.00 | |
| 17_P | 20_H | 2.77 | 1.00 | |
| 32_L | 212_A | 2.736 | 1.00 | |
| 6_E | 65_L | 2.611 | 1.00 | |
| 210_D | 222_Q | 2.603 | 1.00 | |
| 27_Q | 30_R | 2.602 | 1.00 | |
| 20_H | 218_K | 2.566 | 1.00 | |
| 123_E | 128_E | 2.49 | 1.00 | |
| 7_L | 10_I | 2.315 | 1.00 | |
| 117_T | 158_E | 2.185 | 1.00 | |
| 67_D | 160_P | 2.162 | 1.00 | |
| 224_D | 227_T | 2.093 | 1.00 | |
| 11_A | 17_P | 2.086 | 1.00 | |
| 98_M | 141_M | 1.996 | 1.00 | |
| 212_A | 219_I | 1.967 | 1.00 | |
| 28_R | 160_P | 1.966 | 1.00 | |
| 8_R | 65_L | 1.931 | 1.00 | |
| 223_G | 227_T | 1.924 | 1.00 | |
| 119_T | 134_L | 1.921 | 1.00 | |
| 122_I | 134_L | 1.897 | 1.00 | |
| 185_S | 189_K | 1.871 | 1.00 | |
| 99_H | 135_K | 1.853 | 1.00 | |
| 124_A | 185_S | 1.836 | 1.00 | |
| 9_N | 23_S | 1.788 | 1.00 | |
| 158_E | 192_P | 1.781 | 1.00 | |
| 30_R | 209_D | 1.759 | 1.00 | |
| 99_H | 134_L | 1.754 | 1.00 | |
| 212_A | 222_Q | 1.752 | 1.00 | |
| 120_A | 124_A | 1.657 | 1.00 | |
| 124_A | 190_Q | 1.635 | 1.00 | |
| 117_T | 120_A | 1.597 | 1.00 | |
| 46_C | 197_V | 1.587 | 1.00 | |
| 99_H | 119_T | 1.575 | 1.00 | |
| 223_G | 228_L | 1.571 | 1.00 | |
| 99_H | 118_L | 1.565 | 1.00 | |
| 124_A | 189_K | 1.554 | 1.00 | |
| 12_L | 18_L | 1.533 | 1.00 | |
| 129_N | 134_L | 1.524 | 1.00 | |
| 115_D | 119_T | 1.508 | 1.00 | |
| 67_D | 80_K | 1.464 | 1.00 | |
| 136_L | 140_E | 1.455 | 1.00 | |
| 12_L | 44_L | 1.451 | 1.00 | |
| 86_Q | 143_G | 1.44 | 1.00 | |
| 187_M | 209_D | 1.433 | 1.00 | |
| 7_L | 49_T | 1.426 | 1.00 | |
| 110_G | 113_A | 1.426 | 1.00 | |
| 8_R | 25_T | 1.417 | 1.00 | |
| 19_V | 48_A | 1.41 | 1.00 | |
| 198_T | 204_V | 1.407 | 0.99 | |
| 75_A | 78_G | 1.401 | 0.99 | |
| 46_C | 163_I | 1.388 | 0.99 | |
| 26_L | 32_L | 1.384 | 0.99 | |
| 103_R | 118_L | 1.371 | 0.99 | |
| 24_L | 212_A | 1.366 | 0.99 | |
| 65_L | 70_P | 1.358 | 0.99 | |
| 7_L | 24_L | 1.33 | 0.99 | |
| 70_P | 73_P | 1.328 | 0.99 | |
| 103_R | 114_D | 1.318 | 0.99 | |
| 97_T | 100_T | 1.31 | 0.99 | |
| 116_A | 120_A | 1.305 | 0.99 | |
| 164_A | 183_L | 1.3 | 0.99 | |
| 48_A | 55_A | 1.287 | 0.99 | |
| 11_A | 60_T | 1.278 | 0.99 | |
| 31_V | 187_M | 1.26 | 0.99 | |
| 103_R | 115_D | 1.243 | 0.98 | |
| 121_A | 156_L | 1.235 | 0.98 | |
| 8_R | 23_S | 1.231 | 0.98 | |
| 99_H | 115_D | 1.229 | 0.98 | |
| 101_H | 153_M | 1.225 | 0.98 | |
| 117_T | 121_A | 1.216 | 0.98 | |
| 184_E | 187_M | 1.207 | 0.98 | |
| 119_T | 123_E | 1.203 | 0.98 | |
| 4_Q | 67_D | 1.202 | 0.98 | |
| 102_A | 156_L | 1.197 | 0.98 | |
| 97_T | 101_H | 1.193 | 0.98 | |
| 99_H | 103_R | 1.185 | 0.98 | |
| 32_L | 222_Q | 1.181 | 0.98 | |
| 45_T | 214_M | 1.173 | 0.98 | |
| 128_E | 134_L | 1.161 | 0.97 | |
| 55_A | 60_T | 1.16 | 0.97 | |
| 187_M | 194_M | 1.153 | 0.97 | |
| 10_I | 55_A | 1.149 | 0.97 | |
| 82_A | 159_S | 1.142 | 0.97 | |
| 180_L | 203_V | 1.122 | 0.97 | |
| 176_Q | 203_V | 1.111 | 0.96 | |
| 27_Q | 210_D | 1.107 | 0.96 | |
| 98_M | 149_M | 1.104 | 0.96 | |
| 31_V | 194_M | 1.102 | 0.96 | |
| 158_E | 190_Q | 1.092 | 0.96 | |
| 50_L | 83_T | 1.087 | 0.96 | |
| 32_L | 210_D | 1.087 | 0.96 | |
| 96_H | 100_T | 1.082 | 0.96 | |
| 9_N | 61_A | 1.082 | 0.96 | |
| 49_T | 195_L | 1.079 | 0.95 | |
| 141_M | 149_M | 1.076 | 0.95 | |
| 84_I | 151_I | 1.074 | 0.95 | |
| 48_A | 64_I | 1.061 | 0.95 | |
| 120_A | 123_E | 1.058 | 0.95 | |
| 22_V | 45_T | 1.057 | 0.95 | |
| 84_I | 164_A | 1.048 | 0.94 | |
| 182_L | 185_S | 1.047 | 0.94 | |
| 162_I | 194_M | 1.044 | 0.94 | |
| 119_T | 128_E | 1.042 | 0.94 | |
| 7_L | 45_T | 1.039 | 0.94 | |
| 122_I | 127_L | 1.037 | 0.94 | |
| 28_R | 67_D | 1.033 | 0.94 | |
| 133_V | 145_M | 1.033 | 0.94 | |
| 186_I | 192_P | 1.03 | 0.94 | |
| 160_P | 192_P | 1.027 | 0.94 | |
| 234_H | 237_T | 1.02 | 0.93 | |
| 125_V | 152_A | 1.008 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2it1A | 2 | 0.9567 | 100 | -0.017 | Contact Map | 0.863 |
| 1v43A | 1 | 0.9606 | 100 | -0.016 | Contact Map | 0.806 |
| 2yyzA | 1 | 0.9567 | 100 | -0.015 | Contact Map | 0.806 |
| 3tuiC | 4 | 0.9646 | 100 | -0.013 | Contact Map | 0.871 |
| 1oxxK | 1 | 0.9606 | 100 | -0.011 | Contact Map | 0.799 |
| 3fvqA | 2 | 0.9606 | 100 | -0.011 | Contact Map | 0.771 |
| 1g291 | 2 | 0.9567 | 100 | -0.011 | Contact Map | 0.888 |
| 1z47A | 2 | 0.9606 | 100 | -0.009 | Contact Map | 0.833 |
| 3rlfA | 2 | 0.9567 | 100 | -0.007 | Contact Map | 0.828 |
| 4fwiB | 1 | 0.9961 | 100 | -0.005 | Contact Map | 0.722 |
Sequence Conservation (Image Generated using WebLogo v3)