| UniProt: | P0A9P4 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11032 | ||
| Length: | 321 (306) | ||
| Sequences: | 23628 | ||
| Seq/Len: | 77.22 |
| TRXB
Paralog alert: 0.93 [within 20: 0.42] - ratio of genomes with paralogs Cluster includes: DHNA DLDH GSHR HCAD NORW STHA TRXB YKGC |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 150_A | 237_V | 3.946 | 1.00 | |
| 148_K | 171_E | 3.671 | 1.00 | |
| 210_E | 222_R | 3.539 | 1.00 | |
| 173_H | 203_H | 3.248 | 1.00 | |
| 171_E | 201_I | 3.22 | 1.00 | |
| 267_Q | 276_Q | 3.146 | 1.00 | |
| 212_T | 222_R | 3.016 | 1.00 | |
| 8_K | 31_Q | 2.772 | 1.00 | |
| 258_E | 265_K | 2.704 | 1.00 | |
| 93_R | 281_G | 2.549 | 1.00 | |
| 123_P | 210_E | 2.546 | 1.00 | |
| 21_A | 110_I | 2.534 | 1.00 | |
| 150_A | 221_V | 2.522 | 1.00 | |
| 9_L | 25_A | 2.478 | 1.00 | |
| 118_R | 247_S | 2.476 | 1.00 | |
| 192_M | 196_E | 2.427 | 1.00 | |
| 8_K | 107_D | 2.366 | 1.00 | |
| 148_K | 238_A | 2.353 | 1.00 | |
| 209_E | 224_R | 2.32 | 1.00 | |
| 207_T | 224_R | 2.314 | 1.00 | |
| 37_G | 84_H | 2.291 | 1.00 | |
| 222_R | 234_S | 2.274 | 1.00 | |
| 10_L | 35_I | 2.19 | 1.00 | |
| 7_S | 33_V | 2.171 | 1.00 | |
| 150_A | 175_I | 2.105 | 1.00 | |
| 212_T | 220_G | 2.1 | 1.00 | |
| 110_I | 310_A | 2.034 | 1.00 | |
| 33_V | 81_I | 2.018 | 1.00 | |
| 148_K | 170_S | 1.976 | 1.00 | |
| 148_K | 173_H | 1.96 | 1.00 | |
| 17_A | 285_A | 1.946 | 1.00 | |
| 10_L | 104_Y | 1.918 | 1.00 | |
| 106_C | 109_L | 1.91 | 1.00 | |
| 260_E | 263_Y | 1.881 | 1.00 | |
| 148_K | 236_D | 1.88 | 1.00 | |
| 220_G | 234_S | 1.878 | 1.00 | |
| 8_K | 33_V | 1.869 | 1.00 | |
| 203_H | 233_E | 1.855 | 1.00 | |
| 116_S | 249_N | 1.852 | 1.00 | |
| 177_R | 207_T | 1.844 | 1.00 | |
| 90_L | 279_I | 1.837 | 1.00 | |
| 179_D | 205_N | 1.825 | 1.00 | |
| 173_H | 201_I | 1.801 | 1.00 | |
| 108_A | 281_G | 1.79 | 1.00 | |
| 283_F | 313_Y | 1.787 | 1.00 | |
| 6_H | 105_T | 1.785 | 1.00 | |
| 209_E | 222_R | 1.764 | 1.00 | |
| 116_S | 251_A | 1.76 | 1.00 | |
| 258_E | 278_S | 1.756 | 1.00 | |
| 35_I | 104_Y | 1.75 | 1.00 | |
| 110_I | 285_A | 1.725 | 1.00 | |
| 203_H | 206_R | 1.707 | 1.00 | |
| 10_L | 33_V | 1.705 | 1.00 | |
| 212_T | 234_S | 1.699 | 1.00 | |
| 94_P | 105_T | 1.687 | 1.00 | |
| 147_Q | 238_A | 1.684 | 1.00 | |
| 303_G | 307_A | 1.658 | 1.00 | |
| 116_S | 247_S | 1.658 | 1.00 | |
| 6_H | 107_D | 1.658 | 1.00 | |
| 113_T | 288_V | 1.617 | 1.00 | |
| 10_L | 95_F | 1.61 | 1.00 | |
| 185_K | 189_K | 1.597 | 1.00 | |
| 206_R | 225_D | 1.591 | 1.00 | |
| 61_T | 64_L | 1.585 | 1.00 | |
| 10_L | 106_C | 1.564 | 1.00 | |
| 11_I | 22_A | 1.551 | 1.00 | |
| 211_V | 240_L | 1.546 | 1.00 | |
| 31_Q | 79_E | 1.544 | 1.00 | |
| 223_L | 235_L | 1.535 | 1.00 | |
| 14_S | 36_T | 1.523 | 1.00 | |
| 70_H | 74_T | 1.522 | 1.00 | |
| 108_A | 283_F | 1.511 | 1.00 | |
| 276_Q | 280_P | 1.504 | 1.00 | |
| 222_R | 232_I | 1.483 | 1.00 | |
| 225_D | 231_N | 1.48 | 1.00 | |
| 89_D | 92_N | 1.475 | 1.00 | |
| 91_Q | 94_P | 1.473 | 1.00 | |
| 266_V | 289_M | 1.469 | 1.00 | |
| 96_R | 103_E | 1.458 | 1.00 | |
| 260_E | 290_D | 1.443 | 1.00 | |
| 206_R | 223_L | 1.404 | 0.99 | |
| 87_K | 98_N | 1.397 | 0.99 | |
| 67_E | 71_E | 1.391 | 0.99 | |
| 266_V | 284_A | 1.388 | 0.99 | |
| 220_G | 236_D | 1.374 | 0.99 | |
| 166_S | 200_I | 1.369 | 0.99 | |
| 71_E | 74_T | 1.365 | 0.99 | |
| 159_V | 174_L | 1.361 | 0.99 | |
| 149_V | 165_L | 1.357 | 0.99 | |
| 224_R | 232_I | 1.356 | 0.99 | |
| 180_G | 188_I | 1.354 | 0.99 | |
| 112_A | 285_A | 1.353 | 0.99 | |
| 94_P | 103_E | 1.349 | 0.99 | |
| 269_G | 276_Q | 1.342 | 0.99 | |
| 176_H | 204_T | 1.334 | 0.99 | |
| 306_A | 310_A | 1.32 | 0.99 | |
| 35_I | 81_I | 1.315 | 0.99 | |
| 90_L | 282_V | 1.313 | 0.99 | |
| 10_L | 97_L | 1.312 | 0.99 | |
| 209_E | 232_I | 1.309 | 0.99 | |
| 264_I | 284_A | 1.307 | 0.99 | |
| 154_G | 176_H | 1.307 | 0.99 | |
| 9_L | 110_I | 1.292 | 0.99 | |
| 167_N | 198_G | 1.288 | 0.99 | |
| 206_R | 233_E | 1.282 | 0.99 | |
| 9_L | 30_L | 1.275 | 0.99 | |
| 83_D | 101_N | 1.262 | 0.99 | |
| 175_I | 235_L | 1.258 | 0.99 | |
| 260_E | 265_K | 1.256 | 0.99 | |
| 225_D | 229_S | 1.251 | 0.99 | |
| 284_A | 288_V | 1.247 | 0.99 | |
| 264_I | 288_V | 1.24 | 0.98 | |
| 223_L | 233_E | 1.237 | 0.98 | |
| 214_D | 219_T | 1.235 | 0.98 | |
| 71_E | 75_K | 1.213 | 0.98 | |
| 175_I | 223_L | 1.189 | 0.98 | |
| 7_S | 89_D | 1.188 | 0.98 | |
| 12_L | 111_I | 1.184 | 0.98 | |
| 213_G | 219_T | 1.181 | 0.98 | |
| 279_I | 282_V | 1.181 | 0.98 | |
| 24_Y | 308_L | 1.18 | 0.98 | |
| 33_V | 104_Y | 1.175 | 0.98 | |
| 152_I | 240_L | 1.169 | 0.97 | |
| 166_S | 171_E | 1.166 | 0.97 | |
| 108_A | 310_A | 1.163 | 0.97 | |
| 181_F | 204_T | 1.158 | 0.97 | |
| 194_K | 197_N | 1.156 | 0.97 | |
| 14_S | 40_K | 1.155 | 0.97 | |
| 218_V | 240_L | 1.141 | 0.97 | |
| 64_L | 67_E | 1.131 | 0.97 | |
| 121_G | 125_E | 1.124 | 0.97 | |
| 283_F | 309_D | 1.106 | 0.96 | |
| 192_M | 202_L | 1.104 | 0.96 | |
| 192_M | 204_T | 1.103 | 0.96 | |
| 11_I | 18_G | 1.101 | 0.96 | |
| 276_Q | 281_G | 1.098 | 0.96 | |
| 225_D | 233_E | 1.094 | 0.96 | |
| 149_V | 239_G | 1.091 | 0.96 | |
| 111_I | 288_V | 1.071 | 0.95 | |
| 189_K | 192_M | 1.069 | 0.95 | |
| 193_D | 197_N | 1.068 | 0.95 | |
| 149_V | 170_S | 1.06 | 0.95 | |
| 219_T | 236_D | 1.056 | 0.95 | |
| 189_K | 193_D | 1.048 | 0.94 | |
| 289_M | 302_T | 1.047 | 0.94 | |
| 173_H | 237_V | 1.04 | 0.94 | |
| 307_A | 311_E | 1.039 | 0.94 | |
| 7_S | 10_L | 1.036 | 0.94 | |
| 208_L | 221_V | 1.031 | 0.94 | |
| 21_A | 285_A | 1.029 | 0.94 | |
| 138_T | 141_G | 1.028 | 0.94 | |
| 99_G | 104_Y | 1.019 | 0.93 | |
| 270_I | 289_M | 1.014 | 0.93 | |
| 193_D | 196_E | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1trbA | 1 | 0.9938 | 100 | 0.203 | Contact Map | 0.77 |
| 2a87A | 2 | 0.9688 | 100 | 0.219 | Contact Map | 0.772 |
| 2q7vA | 2 | 0.9688 | 100 | 0.219 | Contact Map | 0.787 |
| 4jnqA | 1 | 0.9688 | 100 | 0.222 | Contact Map | 0.743 |
| 2q0lA | 2 | 0.9439 | 100 | 0.225 | Contact Map | 0.73 |
| 4a5lA | 2 | 0.9502 | 100 | 0.226 | Contact Map | 0.769 |
| 3r9uA | 2 | 0.947 | 100 | 0.227 | Contact Map | 0.763 |
| 4gcmA | 2 | 0.9657 | 100 | 0.233 | Contact Map | 0.799 |
| 1vdcA | 1 | 0.9688 | 100 | 0.233 | Contact Map | 0.76 |
| 3ctyA | 2 | 0.9564 | 100 | 0.237 | Contact Map | 0.777 |
Sequence Conservation (Image Generated using WebLogo v3)