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YFCV - Uncharacterized fimbrial-like protein YfcV
UniProt: P77288 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14125
Length: 187 (177)
Sequences: 1411
Seq/Len: 7.97
YFCV
Paralog alert: 0.94 [within 20: 0.77] - ratio of genomes with paralogs
Cluster includes: ELFA FIMA1 FIMF FIMG FIMI SFMA SFMF YADN YBGD YCBU YCBV YDER YDES YFCP YFCV YGIL YRAH
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
123_L 162_A 3.323 1.00
90_M 184_I 3.148 1.00
119_N 172_D 2.795 1.00
124_A 163_W 2.736 1.00
124_A 165_V 2.548 1.00
164_L 176_F 2.408 1.00
66_N 69_T 2.408 1.00
46_V 80_Q 2.32 1.00
76_Q 157_T 2.225 1.00
105_N 122_S 2.139 1.00
126_G 163_W 2.123 1.00
120_N 171_P 2.116 1.00
44_S 81_D 2.096 1.00
109_I 176_F 2.017 1.00
46_V 78_R 1.962 1.00
46_V 49_D 1.948 1.00
127_D 131_T 1.892 1.00
107_Y 180_T 1.869 1.00
107_Y 135_S 1.855 1.00
65_K 69_T 1.777 1.00
98_V 104_G 1.627 1.00
59_I 71_T 1.624 1.00
123_L 178_A 1.617 1.00
56_M 176_F 1.555 1.00
49_D 78_R 1.546 1.00
124_A 132_S 1.537 1.00
40_D 61_A 1.521 1.00
92_T 158_L 1.5 1.00
99_S 167_A 1.455 0.99
49_D 52_L 1.424 0.99
76_Q 159_N 1.409 0.99
6_K 9_I 1.389 0.99
44_S 80_Q 1.353 0.99
74_N 161_K 1.347 0.99
64_L 166_G 1.344 0.99
56_M 164_L 1.322 0.98
121_V 164_L 1.307 0.98
57_G 176_F 1.28 0.98
64_L 167_A 1.28 0.98
19_T 23_T 1.248 0.98
78_R 157_T 1.224 0.97
107_Y 178_A 1.221 0.97
8_A 11_A 1.219 0.97
118_F 121_V 1.21 0.97
52_L 77_I 1.19 0.96
11_A 14_V 1.188 0.96
99_S 122_S 1.182 0.96
38_I 59_I 1.181 0.96
26_A 29_N 1.181 0.96
37_T 58_D 1.179 0.96
130_G 161_K 1.164 0.96
74_N 159_N 1.16 0.96
11_A 16_G 1.158 0.96
19_T 22_A 1.157 0.96
134_K 137_M 1.152 0.96
18_F 21_T 1.12 0.95
52_L 182_F 1.116 0.94
64_L 121_V 1.11 0.94
96_G 107_Y 1.109 0.94
15_M 18_F 1.109 0.94
75_F 125_I 1.1 0.94
42_V 156_Q 1.1 0.94
4_F 8_A 1.097 0.94
57_G 122_S 1.09 0.94
59_I 164_L 1.088 0.93
5_V 8_A 1.081 0.93
67_N 120_N 1.08 0.93
33_R 179_N 1.077 0.93
161_K 178_A 1.075 0.93
105_N 165_V 1.065 0.92
93_T 185_T 1.065 0.92
70_T 163_W 1.061 0.92
64_L 171_P 1.05 0.92
166_G 171_P 1.049 0.92
120_N 169_D 1.049 0.92
107_Y 123_L 1.046 0.92
111_N 116_A 1.044 0.91
72_P 163_W 1.039 0.91
160_F 182_F 1.037 0.91
10_A 13_M 1.037 0.91
13_M 16_G 1.032 0.91
56_M 124_A 1.023 0.90
9_I 17_A 1.019 0.90
10_A 15_M 1.001 0.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2jmrA10.81281000.232Contact Map0.597
2jtyA10.83421000.258Contact Map0.698
2xg5B10.88241000.264Contact Map0.695
2uy6B20.80211000.27Contact Map0.832
1pdkB10.78611000.287Contact Map0.664
3bwuF10.74331000.335Contact Map0.752
4dwhB20.748799.90.348Contact Map0.729
2w07B10.770199.90.362Contact Map0.674
3bfqG10.700599.90.371Contact Map0.675
3jwnH20.86199.90.432Contact Map0.672
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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