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OPENSEQ.org
YDES - Uncharacterized fimbrial-like protein YdeS
UniProt: P77789 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13801
Length: 176 (160)
Sequences: 1509
Seq/Len: 9.43
YDES
Paralog alert: 0.95 [within 20: 0.80] - ratio of genomes with paralogs
Cluster includes: ELFA FIMA1 FIMF FIMG FIMI SFMA SFMF YADN YBGD YCBU YCBV YDER YDES YFCP YFCV YGIL YRAH
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
115_I 151_A 3.338 1.00
111_S 161_N 3.034 1.00
61_T 64_S 3.018 1.00
85_V 173_L 2.983 1.00
116_E 152_R 2.843 1.00
116_E 154_K 2.678 1.00
72_Q 146_I 2.446 1.00
153_L 165_V 2.439 1.00
100_L 114_G 2.352 1.00
118_L 152_R 2.341 1.00
41_S 76_S 2.258 1.00
39_T 77_E 2.25 1.00
112_G 160_V 2.22 1.00
41_S 74_T 2.131 1.00
103_L 165_V 2.104 1.00
41_S 44_S 2.089 1.00
115_I 167_A 2.085 1.00
101_L 169_A 2.014 1.00
101_L 127_L 1.88 1.00
60_P 64_S 1.827 1.00
119_D 123_R 1.825 1.00
35_D 56_A 1.735 1.00
51_L 165_V 1.596 1.00
65_T 152_R 1.578 1.00
116_E 124_P 1.559 1.00
59_F 155_S 1.554 1.00
54_N 66_S 1.532 1.00
72_Q 148_P 1.514 1.00
113_L 153_L 1.453 1.00
139_L 145_N 1.451 1.00
74_T 146_I 1.44 1.00
70_P 150_S 1.388 0.99
87_V 147_L 1.387 0.99
93_E 99_T 1.38 0.99
47_F 73_I 1.36 0.99
39_T 76_S 1.359 0.99
100_L 154_K 1.355 0.99
94_D 156_T 1.346 0.99
44_S 74_T 1.338 0.99
91_G 101_L 1.327 0.99
65_T 116_E 1.302 0.99
52_Q 67_P 1.292 0.99
52_Q 165_V 1.292 0.99
51_L 115_I 1.287 0.99
59_F 160_V 1.23 0.98
101_L 167_A 1.229 0.98
51_L 153_L 1.215 0.98
47_F 171_F 1.202 0.98
155_S 160_V 1.2 0.98
44_S 47_F 1.18 0.97
59_F 156_T 1.179 0.97
110_A 113_L 1.169 0.97
32_R 53_K 1.168 0.97
109_T 164_L 1.168 0.97
94_D 114_G 1.161 0.97
18_Y 21_L 1.153 0.97
90_N 128_N 1.143 0.97
21_L 24_D 1.135 0.96
122_M 150_S 1.123 0.96
25_S 171_F 1.106 0.96
68_A 152_R 1.105 0.96
136_W 139_L 1.097 0.95
101_L 115_I 1.095 0.95
28_K 168_S 1.093 0.95
54_N 153_L 1.091 0.95
65_T 118_L 1.074 0.95
58_Q 66_S 1.074 0.95
126_K 129_D 1.069 0.95
130_L 138_P 1.067 0.94
88_A 174_E 1.067 0.94
59_F 113_L 1.06 0.94
33_V 151_A 1.041 0.93
71_F 117_I 1.029 0.93
65_T 154_K 1.027 0.93
37_G 145_N 1.026 0.93
108_N 164_L 1.018 0.92
62_T 112_G 1.017 0.92
61_T 155_S 1.005 0.92
98_N 101_L 1.005 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2jmrA10.88071000.246Contact Map0.647
2xg5B10.93181000.286Contact Map0.684
2jtyA10.88641000.292Contact Map0.699
2uy6B20.85231000.309Contact Map0.813
1pdkB10.84661000.318Contact Map0.651
3bwuF10.80681000.344Contact Map0.788
4dwhB20.795599.90.375Contact Map0.731
2w07B10.801199.90.396Contact Map0.673
3bfqG10.744399.90.4Contact Map0.695
3jwnH20.886499.90.444Contact Map0.734
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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