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YDER - Uncharacterized fimbrial-like protein YdeR
UniProt: P77294 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13800
Length: 167 (163)
Sequences: 1527
Seq/Len: 9.37
YDER
Paralog alert: 0.95 [within 20: 0.80] - ratio of genomes with paralogs
Cluster includes: ELFA FIMA1 FIMF FIMG FIMI SFMA SFMF YADN YBGD YCBU YCBV YDER YDES YFCP YFCV YGIL YRAH
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
109_I 142_A 3.172 1.00
84_V 164_Y 3.006 1.00
105_E 152_S 2.981 1.00
60_Q 63_S 2.793 1.00
110_E 143_R 2.745 1.00
110_E 145_I 2.673 1.00
144_A 156_I 2.534 1.00
71_T 137_Q 2.458 1.00
112_R 143_R 2.313 1.00
97_Y 108_Q 2.152 1.00
40_T 76_D 2.053 1.00
109_I 158_A 1.976 1.00
98_Y 121_N 1.974 1.00
42_Q 73_S 1.933 1.00
106_N 151_A 1.929 1.00
98_Y 160_I 1.897 1.00
59_Q 63_S 1.735 1.00
90_G 98_Y 1.677 1.00
110_E 118_A 1.629 1.00
50_L 156_I 1.611 1.00
36_A 55_T 1.534 1.00
53_L 65_S 1.533 1.00
113_D 117_A 1.524 1.00
106_N 149_G 1.505 1.00
71_T 139_P 1.496 1.00
50_L 109_I 1.466 1.00
58_L 146_T 1.459 1.00
43_T 46_A 1.435 1.00
86_A 138_F 1.416 0.99
97_Y 145_I 1.409 0.99
64_A 110_E 1.403 0.99
92_T 96_G 1.361 0.99
51_G 156_I 1.355 0.99
42_Q 75_T 1.343 0.99
107_I 144_A 1.327 0.99
51_G 66_G 1.324 0.99
73_S 137_Q 1.304 0.99
103_T 155_T 1.297 0.99
69_N 141_K 1.295 0.99
100_N 156_I 1.28 0.99
116_D 141_K 1.273 0.99
46_A 72_L 1.264 0.98
40_T 75_T 1.26 0.98
58_L 147_V 1.24 0.98
93_D 147_V 1.239 0.98
104_A 107_I 1.237 0.98
146_T 151_A 1.232 0.98
43_T 73_S 1.215 0.98
18_T 21_L 1.198 0.98
111_L 121_N 1.198 0.98
13_F 17_F 1.198 0.98
64_A 143_R 1.18 0.97
93_D 108_Q 1.151 0.97
6_K 10_L 1.146 0.97
38_P 136_A 1.145 0.97
12_T 16_L 1.141 0.97
46_A 162_V 1.138 0.96
7_R 14_C 1.127 0.96
120_K 123_D 1.126 0.96
58_L 151_A 1.113 0.96
67_W 143_R 1.11 0.96
33_R 52_D 1.098 0.95
5_H 13_F 1.091 0.95
50_L 144_A 1.085 0.95
57_N 65_S 1.079 0.95
98_Y 158_A 1.077 0.95
58_L 149_G 1.061 0.94
87_I 165_T 1.059 0.94
58_L 107_I 1.047 0.94
8_F 11_A 1.047 0.94
70_I 111_L 1.045 0.94
26_V 162_V 1.043 0.93
18_T 22_Q 1.041 0.93
9_L 16_L 1.04 0.93
34_V 53_L 1.039 0.93
29_T 159_L 1.036 0.93
32_G 88_V 1.03 0.93
89_T 122_G 1.026 0.93
148_N 151_A 1.02 0.92
64_A 112_R 1.019 0.92
5_H 8_F 1.013 0.92
127_V 130_D 1.008 0.92
7_R 13_F 1.008 0.92
64_A 145_I 1.006 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2jmrA10.86831000.268Contact Map0.615
2xg5B10.95211000.278Contact Map0.693
2jtyA10.88621000.29Contact Map0.696
2uy6B20.87431000.297Contact Map0.796
1pdkB10.84431000.323Contact Map0.624
3bfqG10.790499.90.342Contact Map0.673
3bwuF10.790499.90.369Contact Map0.807
4dwhB20.790499.90.378Contact Map0.753
2w07B10.820499.90.379Contact Map0.657
3jwnH20.910299.90.437Contact Map0.693
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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