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OPENSEQ.org
YGCN - Probable electron transfer flavoprotein-quinone oxidoreductase YgcN
UniProt: Q46904 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13121
Length: 423 (362)
Sequences: 6192
Seq/Len: 17.10
YGCN
Paralog alert: 0.82 [within 20: 0.29] - ratio of genomes with paralogs
Cluster includes: CBRA FIXC UBIF UBIH VISC YDIS YGCN
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
31_L 120_I 4.276 1.00
19_C 151_V 3.925 1.00
8_I 138_V 3.881 1.00
35_R 124_T 3.485 1.00
343_H 347_E 3.45 1.00
8_I 147_A 3.377 1.00
6_D 148_R 3.274 1.00
15_A 315_A 3.269 1.00
152_L 160_L 3.162 1.00
6_D 29_S 3.1 1.00
5_C 31_L 2.878 1.00
111_E 114_K 2.853 1.00
127_A 139_I 2.792 1.00
127_A 163_R 2.709 1.00
184_S 266_E 2.69 1.00
8_I 33_L 2.653 1.00
244_P 247_E 2.577 1.00
22_R 323_A 2.542 1.00
124_T 141_G 2.521 1.00
26_A 327_I 2.463 1.00
153_A 295_V 2.412 1.00
128_L 150_V 2.385 1.00
125_V 138_V 2.382 1.00
324_Q 345_N 2.297 1.00
15_A 295_V 2.244 1.00
18_A 316_L 2.22 1.00
33_L 145_L 2.203 1.00
154_E 158_S 2.17 1.00
9_I 19_C 2.152 1.00
139_I 144_I 2.142 1.00
319_A 323_A 2.112 1.00
288_A 293_L 2.071 1.00
20_A 32_L 2.069 1.00
325_T 345_N 2.025 1.00
106_P 110_A 2.018 1.00
151_V 295_V 2.003 1.00
134_R 146_R 1.997 1.00
131_E 134_R 1.995 1.00
31_L 145_L 1.987 1.00
7_I 23_C 1.974 1.00
137_G 146_R 1.974 1.00
33_L 140_C 1.972 1.00
19_C 295_V 1.959 1.00
126_D 141_G 1.951 1.00
147_A 150_V 1.925 1.00
112_A 117_V 1.914 1.00
19_C 319_A 1.882 1.00
7_I 28_L 1.848 1.00
321_A 345_N 1.841 1.00
129_Y 137_G 1.834 1.00
131_E 146_R 1.83 1.00
325_T 338_L 1.815 1.00
149_Y 339_F 1.815 1.00
8_I 145_L 1.813 1.00
288_A 340_P 1.793 1.00
286_Q 289_G 1.782 1.00
151_V 293_L 1.775 1.00
123_A 140_C 1.73 1.00
159_V 163_R 1.728 1.00
152_L 294_L 1.71 1.00
129_Y 139_I 1.708 1.00
321_A 325_T 1.696 1.00
4_D 146_R 1.695 1.00
29_S 118_E 1.692 1.00
6_D 31_L 1.69 1.00
164_H 292_W 1.67 1.00
140_C 145_L 1.655 1.00
21_L 112_A 1.652 1.00
325_T 341_L 1.648 1.00
300_R 318_G 1.646 1.00
237_S 240_Q 1.643 1.00
135_V 150_V 1.637 1.00
21_L 111_E 1.62 1.00
317_T 349_S 1.602 1.00
10_I 150_V 1.601 1.00
137_G 144_I 1.557 1.00
51_T 55_A 1.548 1.00
8_I 31_L 1.535 1.00
12_A 34_E 1.534 1.00
138_V 150_V 1.533 1.00
287_Y 350_L 1.519 1.00
19_C 23_C 1.51 1.00
4_D 148_R 1.508 1.00
5_C 8_I 1.502 1.00
18_A 22_R 1.48 1.00
125_V 160_L 1.475 1.00
14_I 312_M 1.472 1.00
28_L 327_I 1.472 1.00
9_I 20_A 1.441 1.00
286_Q 343_H 1.441 1.00
295_V 342_Y 1.431 1.00
33_L 138_V 1.427 1.00
37_E 122_G 1.427 1.00
151_V 326_L 1.427 1.00
293_L 322_A 1.42 1.00
120_I 123_A 1.405 0.99
250_T 253_K 1.389 0.99
12_A 39_P 1.381 0.99
136_C 146_R 1.373 0.99
347_E 351_L 1.351 0.99
123_A 142_D 1.35 0.99
246_S 250_T 1.341 0.99
5_C 118_E 1.333 0.99
259_R 263_K 1.331 0.99
289_G 292_W 1.33 0.99
318_G 346_V 1.33 0.99
151_V 322_A 1.325 0.99
10_I 125_V 1.314 0.99
325_T 328_S 1.311 0.99
288_A 336_Q 1.308 0.99
156_A 303_V 1.303 0.99
24_A 117_V 1.303 0.99
160_L 292_W 1.301 0.99
9_I 30_V 1.282 0.99
158_S 161_A 1.273 0.99
109_V 119_C 1.254 0.99
6_D 28_L 1.251 0.99
304_N 314_M 1.249 0.99
207_S 210_I 1.247 0.99
161_A 298_A 1.245 0.98
303_V 318_G 1.241 0.98
33_L 120_I 1.232 0.98
130_E 289_G 1.228 0.98
19_C 326_L 1.224 0.98
359_Q 363_A 1.22 0.98
328_S 341_L 1.213 0.98
152_L 292_W 1.211 0.98
21_L 25_R 1.203 0.98
287_Y 343_H 1.2 0.98
310_R 313_D 1.191 0.98
12_A 17_T 1.189 0.98
30_V 117_V 1.188 0.98
123_A 143_D 1.181 0.98
157_N 162_E 1.154 0.97
58_L 62_H 1.151 0.97
111_E 115_E 1.143 0.97
23_C 323_A 1.143 0.97
125_V 128_L 1.14 0.97
135_V 291_G 1.126 0.97
341_L 345_N 1.125 0.97
60_Q 110_A 1.122 0.97
130_E 290_N 1.116 0.96
252_F 258_V 1.106 0.96
320_Q 324_Q 1.103 0.96
130_E 135_V 1.099 0.96
19_C 322_A 1.096 0.96
304_N 358_Y 1.093 0.96
130_E 291_G 1.092 0.96
10_I 160_L 1.09 0.96
131_E 136_C 1.085 0.96
288_A 339_F 1.08 0.95
340_P 344_H 1.072 0.95
52_H 55_A 1.071 0.95
120_I 145_L 1.07 0.95
257_A 260_P 1.069 0.95
51_T 57_L 1.069 0.95
165_G 168_T 1.065 0.95
99_V 104_F 1.064 0.95
204_L 207_S 1.061 0.95
290_N 336_Q 1.059 0.95
109_V 121_P 1.053 0.95
288_A 343_H 1.053 0.95
149_Y 293_L 1.047 0.94
110_A 113_E 1.047 0.94
125_V 163_R 1.046 0.94
129_Y 144_I 1.041 0.94
131_E 137_G 1.038 0.94
321_A 324_Q 1.036 0.94
34_E 121_P 1.028 0.94
328_S 345_N 1.026 0.94
323_A 327_I 1.022 0.93
33_L 123_A 1.015 0.93
149_Y 329_A 1.012 0.93
128_L 164_H 1.011 0.93
7_I 30_V 1.01 0.93
28_L 330_C 1.008 0.93
23_C 28_L 1.006 0.93
169_R 285_V 1.006 0.93
128_L 152_L 1.004 0.93
294_L 299_L 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2gmhA20.96221000.384Contact Map0.77
3atrA10.93141000.443Contact Map0.745
3cgvA10.89361000.487Contact Map0.76
2x3nA10.89831000.501Contact Map0.751
3e1tA10.94091000.505Contact Map0.743
4k22A20.81561000.507Contact Map0.739
2qa2A10.91021000.51Contact Map0.761
4n9xA10.90781000.511Contact Map0.688
2qa1A10.91021000.516Contact Map0.775
3fmwA30.92431000.523Contact Map0.706
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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