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OPENSEQ.org
YDIS - Probable electron transfer flavoprotein-quinone oxidoreductase YdiS
UniProt: P77337 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13978
Length: 429 (369)
Sequences: 6120
Seq/Len: 16.59
YDIS
Paralog alert: 0.76 [within 20: 0.23] - ratio of genomes with paralogs
Cluster includes: CBRA FIXC UBIF UBIH VISC YDIS YGCN
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
32_L 126_I 4.198 1.00
9_I 144_V 4.142 1.00
20_A 157_I 3.841 1.00
349_K 353_E 3.672 1.00
36_R 130_R 3.491 1.00
9_I 153_A 3.461 1.00
158_L 166_L 3.198 1.00
16_A 320_A 3.138 1.00
7_D 154_N 3.046 1.00
133_A 169_S 2.959 1.00
7_D 30_D 2.953 1.00
117_Q 120_Q 2.931 1.00
133_A 145_Q 2.793 1.00
6_F 32_L 2.671 1.00
16_A 300_V 2.654 1.00
130_R 147_G 2.648 1.00
190_G 272_K 2.566 1.00
131_V 144_V 2.451 1.00
27_A 332_I 2.442 1.00
9_I 34_I 2.43 1.00
250_S 253_Q 2.422 1.00
23_V 328_A 2.362 1.00
145_Q 150_I 2.331 1.00
21_A 33_V 2.297 1.00
159_A 300_V 2.288 1.00
134_L 156_V 2.258 1.00
34_I 151_L 2.254 1.00
329_T 351_E 2.236 1.00
293_V 298_M 2.23 1.00
34_I 146_A 2.226 1.00
19_V 321_I 2.219 1.00
143_G 152_E 2.152 1.00
293_V 346_A 2.122 1.00
157_I 300_V 2.111 1.00
140_K 152_E 2.095 1.00
135_V 143_G 2.086 1.00
112_P 116_E 2.086 1.00
20_A 300_V 2.036 1.00
146_A 151_L 2.025 1.00
132_D 147_G 2.006 1.00
8_A 24_M 1.999 1.00
8_A 29_L 1.999 1.00
155_V 345_L 1.994 1.00
324_A 328_A 1.993 1.00
157_I 298_M 1.981 1.00
137_E 152_E 1.977 1.00
160_D 164_S 1.972 1.00
20_A 324_A 1.969 1.00
32_L 151_L 1.949 1.00
22_L 117_Q 1.946 1.00
330_T 351_E 1.934 1.00
10_V 20_A 1.922 1.00
5_K 154_N 1.919 1.00
330_T 344_S 1.912 1.00
129_V 146_A 1.883 1.00
137_E 140_K 1.867 1.00
7_D 32_L 1.832 1.00
153_A 156_V 1.832 1.00
13_A 40_A 1.814 1.00
158_L 299_I 1.802 1.00
11_V 156_V 1.795 1.00
135_V 145_Q 1.78 1.00
30_D 124_Q 1.758 1.00
9_I 151_L 1.753 1.00
118_A 123_A 1.709 1.00
129_V 149_D 1.705 1.00
326_A 351_E 1.66 1.00
291_Q 294_N 1.636 1.00
5_K 152_E 1.611 1.00
165_M 169_S 1.61 1.00
141_V 156_V 1.609 1.00
143_G 150_I 1.606 1.00
6_F 9_I 1.589 1.00
126_I 149_D 1.557 1.00
157_I 331_V 1.544 1.00
9_I 32_L 1.541 1.00
326_A 330_T 1.538 1.00
29_L 332_I 1.537 1.00
61_G 64_V 1.532 1.00
144_V 156_V 1.529 1.00
142_T 152_E 1.52 1.00
292_L 356_C 1.51 1.00
170_L 297_V 1.493 1.00
10_V 21_A 1.481 1.00
300_V 348_Y 1.48 1.00
330_T 347_Q 1.479 1.00
34_I 126_I 1.478 1.00
38_D 128_G 1.475 1.00
22_L 118_A 1.463 1.00
252_P 256_E 1.456 1.00
298_M 327_A 1.453 1.00
305_G 323_S 1.451 1.00
20_A 24_M 1.447 1.00
34_I 144_V 1.436 1.00
136_R 294_N 1.428 1.00
243_D 246_H 1.422 1.00
294_N 297_V 1.414 1.00
7_D 29_L 1.407 0.99
322_A 355_S 1.406 0.99
291_Q 349_K 1.388 0.99
286_L 308_L 1.382 0.99
25_A 123_A 1.377 0.99
164_S 167_G 1.376 0.99
323_S 352_L 1.364 0.99
172_M 289_V 1.352 0.99
13_A 18_S 1.348 0.99
6_F 124_Q 1.347 0.99
333_A 347_Q 1.342 0.99
20_A 331_V 1.341 0.99
126_I 129_V 1.333 0.99
56_E 64_V 1.332 0.99
57_A 325_Q 1.323 0.99
15_V 317_M 1.315 0.99
11_V 131_V 1.305 0.99
167_G 303_A 1.298 0.99
105_V 110_L 1.294 0.99
292_L 349_K 1.273 0.99
126_I 151_L 1.266 0.99
293_V 345_L 1.252 0.99
24_M 29_L 1.249 0.99
353_E 358_M 1.248 0.99
24_M 328_A 1.246 0.98
166_L 297_V 1.243 0.98
309_N 319_L 1.236 0.98
157_I 327_A 1.231 0.98
115_M 125_F 1.227 0.98
13_A 35_E 1.224 0.98
190_G 231_D 1.212 0.98
131_V 166_L 1.208 0.98
19_V 23_V 1.199 0.98
45_M 48_G 1.187 0.98
190_G 274_L 1.183 0.98
347_Q 350_R 1.18 0.98
265_R 269_S 1.161 0.97
253_Q 257_D 1.156 0.97
22_L 58_I 1.146 0.97
190_G 232_S 1.125 0.97
116_E 119_E 1.119 0.96
10_V 31_V 1.118 0.96
117_Q 121_A 1.117 0.96
293_V 349_K 1.115 0.96
325_Q 329_T 1.109 0.96
131_V 134_L 1.105 0.96
31_V 123_A 1.102 0.96
347_Q 351_E 1.096 0.96
155_V 298_M 1.087 0.96
330_T 333_A 1.086 0.96
192_T 195_Q 1.08 0.95
308_L 323_S 1.078 0.95
26_R 117_Q 1.078 0.95
34_I 129_V 1.073 0.95
333_A 351_E 1.069 0.95
22_L 26_R 1.066 0.95
256_E 259_K 1.062 0.95
155_V 334_A 1.061 0.95
24_M 331_V 1.057 0.95
165_M 168_R 1.056 0.95
137_E 143_G 1.048 0.94
365_R 369_A 1.045 0.94
134_L 166_L 1.037 0.94
29_L 335_K 1.037 0.94
295_E 342_A 1.034 0.94
186_K 234_S 1.034 0.94
136_R 141_V 1.03 0.94
56_E 63_A 1.029 0.94
23_V 58_I 1.024 0.93
309_N 364_F 1.015 0.93
132_D 145_Q 1.009 0.93
326_A 329_T 1.007 0.93
258_F 264_I 1.003 0.93
134_L 141_V 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2gmhA20.96271000.383Contact Map0.781
3atrA10.91841000.403Contact Map0.757
3cgvA10.89981000.445Contact Map0.776
2x3nA10.86951000.474Contact Map0.756
4k22A20.80651000.479Contact Map0.763
4n9xA10.89741000.489Contact Map0.705
3e1tA10.95341000.489Contact Map0.757
2qa2A10.89511000.5Contact Map0.772
4j33A20.85551000.506Contact Map0.697
2qa1A10.89511000.506Contact Map0.79
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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