| UniProt: | P31456 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11714 | ||
| Length: | 354 (313) | ||
| Sequences: | 10774 | ||
| Seq/Len: | 34.42 |
| CBRA
Paralog alert: 0.83 [within 20: 0.32] - ratio of genomes with paralogs Cluster includes: CBRA FIXC UBIF UBIH VISC YDIS YGCN |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 29_I | 118_Y | 4.235 | 1.00 | |
| 33_K | 122_L | 3.831 | 1.00 | |
| 5_D | 149_R | 3.328 | 1.00 | |
| 7_A | 148_A | 3.314 | 1.00 | |
| 18_L | 152_V | 3.217 | 1.00 | |
| 5_D | 27_Q | 3.196 | 1.00 | |
| 312_W | 316_R | 3.17 | 1.00 | |
| 7_A | 135_V | 3.084 | 1.00 | |
| 153_G | 161_V | 2.708 | 1.00 | |
| 125_K | 164_H | 2.6 | 1.00 | |
| 14_A | 289_A | 2.542 | 1.00 | |
| 125_K | 136_I | 2.484 | 1.00 | |
| 134_H | 147_T | 2.472 | 1.00 | |
| 7_A | 31_L | 2.418 | 1.00 | |
| 4_F | 29_I | 2.351 | 1.00 | |
| 121_S | 140_D | 2.35 | 1.00 | |
| 123_C | 135_V | 2.321 | 1.00 | |
| 31_L | 146_I | 2.317 | 1.00 | |
| 68_D | 109_S | 2.314 | 1.00 | |
| 127_W | 134_H | 2.296 | 1.00 | |
| 14_A | 271_I | 2.272 | 1.00 | |
| 105_L | 109_S | 2.252 | 1.00 | |
| 136_I | 145_H | 2.237 | 1.00 | |
| 154_A | 271_I | 2.118 | 1.00 | |
| 17_A | 290_L | 2.116 | 1.00 | |
| 20_R | 110_L | 2.086 | 1.00 | |
| 31_L | 137_F | 2.071 | 1.00 | |
| 264_G | 309_T | 2.044 | 1.00 | |
| 6_V | 26_M | 2.02 | 1.00 | |
| 27_Q | 116_E | 1.986 | 1.00 | |
| 126_I | 151_L | 1.968 | 1.00 | |
| 137_F | 146_I | 1.966 | 1.00 | |
| 153_G | 270_L | 1.91 | 1.00 | |
| 134_H | 145_H | 1.903 | 1.00 | |
| 132_K | 147_T | 1.9 | 1.00 | |
| 21_K | 297_R | 1.874 | 1.00 | |
| 19_A | 30_A | 1.865 | 1.00 | |
| 6_V | 22_L | 1.849 | 1.00 | |
| 127_W | 136_I | 1.846 | 1.00 | |
| 264_G | 269_F | 1.832 | 1.00 | |
| 5_D | 29_I | 1.826 | 1.00 | |
| 155_D | 159_S | 1.816 | 1.00 | |
| 228_T | 232_E | 1.812 | 1.00 | |
| 8_I | 18_L | 1.8 | 1.00 | |
| 54_A | 287_S | 1.798 | 1.00 | |
| 129_E | 147_T | 1.785 | 1.00 | |
| 150_Y | 308_N | 1.781 | 1.00 | |
| 111_I | 115_V | 1.775 | 1.00 | |
| 118_Y | 121_S | 1.772 | 1.00 | |
| 293_T | 297_R | 1.77 | 1.00 | |
| 7_A | 146_I | 1.751 | 1.00 | |
| 29_I | 146_I | 1.742 | 1.00 | |
| 262_V | 265_K | 1.716 | 1.00 | |
| 165_L | 268_A | 1.704 | 1.00 | |
| 121_S | 137_F | 1.694 | 1.00 | |
| 227_F | 231_K | 1.653 | 1.00 | |
| 18_L | 22_L | 1.648 | 1.00 | |
| 59_I | 66_P | 1.633 | 1.00 | |
| 122_L | 139_A | 1.632 | 1.00 | |
| 160_M | 164_H | 1.631 | 1.00 | |
| 129_E | 132_K | 1.621 | 1.00 | |
| 68_D | 110_L | 1.584 | 1.00 | |
| 295_I | 299_V | 1.576 | 1.00 | |
| 57_S | 294_D | 1.563 | 1.00 | |
| 23_A | 115_V | 1.56 | 1.00 | |
| 122_L | 138_R | 1.554 | 1.00 | |
| 128_R | 265_K | 1.528 | 1.00 | |
| 18_L | 271_I | 1.502 | 1.00 | |
| 299_V | 314_A | 1.501 | 1.00 | |
| 152_V | 271_I | 1.5 | 1.00 | |
| 129_E | 134_H | 1.488 | 1.00 | |
| 152_V | 269_F | 1.472 | 1.00 | |
| 226_R | 229_T | 1.469 | 1.00 | |
| 20_R | 111_I | 1.457 | 1.00 | |
| 21_K | 61_D | 1.451 | 1.00 | |
| 295_I | 314_A | 1.443 | 1.00 | |
| 133_W | 151_L | 1.429 | 1.00 | |
| 133_W | 267_N | 1.42 | 1.00 | |
| 299_V | 307_L | 1.417 | 1.00 | |
| 13_P | 286_I | 1.417 | 1.00 | |
| 298_S | 314_A | 1.412 | 1.00 | |
| 7_A | 29_I | 1.405 | 0.99 | |
| 9_I | 151_L | 1.394 | 0.99 | |
| 262_V | 312_W | 1.388 | 0.99 | |
| 20_R | 24_G | 1.386 | 0.99 | |
| 4_F | 7_A | 1.382 | 0.99 | |
| 68_D | 112_P | 1.372 | 0.99 | |
| 159_S | 162_R | 1.36 | 0.99 | |
| 148_A | 151_L | 1.359 | 0.99 | |
| 11_L | 16_S | 1.353 | 0.99 | |
| 67_V | 70_I | 1.348 | 0.99 | |
| 271_I | 311_Y | 1.339 | 0.99 | |
| 264_G | 305_E | 1.336 | 0.99 | |
| 8_I | 28_V | 1.327 | 0.99 | |
| 67_V | 71_A | 1.318 | 0.99 | |
| 17_A | 21_K | 1.316 | 0.99 | |
| 68_D | 71_A | 1.311 | 0.99 | |
| 157_A | 277_F | 1.31 | 0.99 | |
| 269_F | 296_L | 1.306 | 0.99 | |
| 20_R | 61_D | 1.298 | 0.99 | |
| 135_V | 151_L | 1.294 | 0.99 | |
| 66_P | 70_I | 1.289 | 0.99 | |
| 123_C | 126_I | 1.264 | 0.99 | |
| 276_G | 292_S | 1.262 | 0.99 | |
| 128_R | 267_N | 1.261 | 0.99 | |
| 26_M | 301_L | 1.26 | 0.99 | |
| 4_F | 116_E | 1.249 | 0.99 | |
| 9_I | 123_C | 1.246 | 0.98 | |
| 123_C | 161_V | 1.242 | 0.98 | |
| 124_R | 139_A | 1.242 | 0.98 | |
| 8_I | 19_A | 1.239 | 0.98 | |
| 110_L | 113_A | 1.235 | 0.98 | |
| 31_L | 118_Y | 1.23 | 0.98 | |
| 5_D | 26_M | 1.223 | 0.98 | |
| 108_K | 119_H | 1.219 | 0.98 | |
| 229_T | 232_E | 1.219 | 0.98 | |
| 137_F | 140_D | 1.217 | 0.98 | |
| 124_R | 136_I | 1.213 | 0.98 | |
| 232_E | 235_S | 1.194 | 0.98 | |
| 128_R | 133_W | 1.193 | 0.98 | |
| 60_R | 294_D | 1.19 | 0.98 | |
| 24_G | 110_L | 1.183 | 0.98 | |
| 152_V | 296_L | 1.182 | 0.98 | |
| 39_T | 120_D | 1.181 | 0.98 | |
| 160_M | 163_R | 1.179 | 0.98 | |
| 299_V | 302_K | 1.177 | 0.98 | |
| 127_W | 145_H | 1.176 | 0.98 | |
| 136_I | 143_E | 1.171 | 0.98 | |
| 11_L | 32_D | 1.165 | 0.97 | |
| 3_H | 149_R | 1.164 | 0.97 | |
| 26_M | 300_L | 1.154 | 0.97 | |
| 118_Y | 146_I | 1.142 | 0.97 | |
| 17_A | 61_D | 1.142 | 0.97 | |
| 299_V | 310_A | 1.141 | 0.97 | |
| 55_Q | 95_Y | 1.128 | 0.97 | |
| 45_P | 48_G | 1.127 | 0.97 | |
| 265_K | 268_A | 1.124 | 0.97 | |
| 295_I | 298_S | 1.122 | 0.97 | |
| 102_A | 105_L | 1.12 | 0.96 | |
| 28_V | 115_V | 1.113 | 0.96 | |
| 294_D | 298_S | 1.095 | 0.96 | |
| 263_C | 312_W | 1.09 | 0.96 | |
| 54_A | 290_L | 1.088 | 0.96 | |
| 150_Y | 269_F | 1.075 | 0.95 | |
| 108_K | 117_V | 1.073 | 0.95 | |
| 292_S | 315_T | 1.072 | 0.95 | |
| 41_G | 108_K | 1.062 | 0.95 | |
| 135_V | 148_A | 1.061 | 0.95 | |
| 278_I | 288_Y | 1.059 | 0.95 | |
| 31_L | 121_S | 1.058 | 0.95 | |
| 138_R | 143_E | 1.054 | 0.95 | |
| 21_K | 293_T | 1.048 | 0.94 | |
| 9_I | 161_V | 1.048 | 0.94 | |
| 309_T | 313_R | 1.045 | 0.94 | |
| 161_V | 268_A | 1.044 | 0.94 | |
| 30_A | 117_V | 1.038 | 0.94 | |
| 229_T | 233_K | 1.031 | 0.94 | |
| 264_G | 312_W | 1.03 | 0.94 | |
| 270_L | 274_A | 1.013 | 0.93 | |
| 118_Y | 144_Q | 1.01 | 0.93 | |
| 22_L | 26_M | 1.01 | 0.93 | |
| 310_A | 313_R | 1.009 | 0.93 | |
| 99_N | 102_A | 1.005 | 0.93 | |
| 198_I | 201_C | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4n9xA | 1 | 0.9746 | 100 | 0.294 | Contact Map | 0.721 |
| 2qa2A | 1 | 0.9548 | 100 | 0.297 | Contact Map | 0.754 |
| 2qa1A | 1 | 0.9548 | 100 | 0.306 | Contact Map | 0.795 |
| 3fmwA | 3 | 0.9605 | 100 | 0.314 | Contact Map | 0.702 |
| 4k2xA | 2 | 0.9576 | 100 | 0.315 | Contact Map | 0.811 |
| 4k5sA | 1 | 0.9605 | 100 | 0.321 | Contact Map | 0.797 |
| 4k22A | 2 | 0.9237 | 100 | 0.323 | Contact Map | 0.768 |
| 2x3nA | 1 | 0.9633 | 100 | 0.324 | Contact Map | 0.775 |
| 3aljA | 1 | 0.9379 | 100 | 0.333 | Contact Map | 0.785 |
| 4bjzA | 1 | 0.9492 | 100 | 0.341 | Contact Map | 0.763 |
Sequence Conservation (Image Generated using WebLogo v3)