May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org
YDJG - Uncharacterized oxidoreductase YdjG
UniProt: P77256 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13483
Length: 326 (321)
Sequences: 11762
Seq/Len: 36.64
YDJG
Paralog alert: 0.83 [within 20: 0.20] - ratio of genomes with paralogs
Cluster includes: DKGA DKGB GPR TAS YAJO YDBC YDHF YDJG YEAE
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
44_E 299_R 3.642 1.00
119_A 162_K 3.352 1.00
73_K 126_G 3.174 1.00
35_R 70_Q 3.032 1.00
267_Y 313_D 2.867 1.00
44_E 48_C 2.821 1.00
118_V 157_L 2.807 1.00
266_R 316_L 2.677 1.00
84_T 130_I 2.608 1.00
115_R 160_E 2.591 1.00
82_V 127_I 2.456 1.00
310_S 313_D 2.391 1.00
266_R 313_D 2.19 1.00
155_N 159_S 2.182 1.00
115_R 156_E 2.161 1.00
134_M 187_I 2.16 1.00
5_P 12_T 2.14 1.00
63_N 66_V 2.13 1.00
261_Q 265_A 2.093 1.00
311_D 315_T 2.065 1.00
118_V 133_Y 2.012 1.00
156_E 159_S 2.007 1.00
156_E 160_E 1.995 1.00
84_T 121_S 1.955 1.00
48_C 299_R 1.942 1.00
129_Y 164_R 1.934 1.00
281_K 314_A 1.92 1.00
134_M 215_Q 1.92 1.00
48_C 302_V 1.898 1.00
118_V 130_I 1.895 1.00
277_A 307_I 1.88 1.00
270_T 300_E 1.87 1.00
17_G 52_L 1.842 1.00
262_P 316_L 1.813 1.00
269_C 307_I 1.805 1.00
39_I 71_A 1.791 1.00
4_I 15_R 1.789 1.00
295_P 299_R 1.749 1.00
130_I 163_I 1.747 1.00
66_V 124_R 1.745 1.00
206_L 210_N 1.731 1.00
111_P 156_E 1.728 1.00
177_R 209_D 1.699 1.00
20_T 53_I 1.689 1.00
111_P 115_R 1.687 1.00
53_I 68_V 1.683 1.00
120_A 124_R 1.681 1.00
57_P 117_E 1.663 1.00
83_E 134_M 1.635 1.00
86_C 114_I 1.633 1.00
163_I 166_I 1.609 1.00
45_A 50_I 1.583 1.00
207_C 214_V 1.58 1.00
34_D 37_I 1.58 1.00
263_L 274_L 1.577 1.00
153_V 156_E 1.57 1.00
39_I 70_Q 1.568 1.00
177_R 181_Q 1.556 1.00
269_C 273_T 1.551 1.00
44_E 47_R 1.551 1.00
115_R 153_V 1.532 1.00
202_E 205_P 1.532 1.00
303_A 306_N 1.525 1.00
39_I 43_L 1.521 1.00
44_E 295_P 1.52 1.00
115_R 119_A 1.518 1.00
76_P 79_Q 1.508 1.00
116_E 120_A 1.502 1.00
39_I 74_K 1.502 1.00
296_E 299_R 1.495 1.00
42_I 71_A 1.488 1.00
259_Q 262_P 1.472 1.00
46_H 80_V 1.46 1.00
37_I 40_D 1.459 1.00
299_R 303_A 1.452 1.00
157_L 163_I 1.449 1.00
69_G 126_G 1.426 1.00
120_A 123_Q 1.425 1.00
154_L 166_I 1.419 1.00
41_T 298_V 1.416 1.00
11_I 81_V 1.404 0.99
270_T 273_T 1.402 0.99
177_R 206_L 1.395 0.99
43_L 47_R 1.391 0.99
66_V 123_Q 1.388 0.99
173_A 206_L 1.384 0.99
119_A 160_E 1.383 0.99
298_V 302_V 1.367 0.99
77_R 127_I 1.366 0.99
172_D 175_H 1.357 0.99
208_R 283_S 1.353 0.99
262_P 265_A 1.344 0.99
315_T 319_E 1.341 0.99
205_P 209_D 1.339 0.99
70_Q 126_G 1.335 0.99
111_P 149_E 1.332 0.99
269_C 274_L 1.327 0.99
165_A 186_D 1.3 0.99
119_A 123_Q 1.292 0.99
3_K 12_T 1.289 0.99
86_C 133_Y 1.287 0.99
65_E 121_S 1.284 0.99
72_L 80_V 1.278 0.99
213_V 287_S 1.275 0.99
180_L 210_N 1.268 0.99
292_A 298_V 1.264 0.99
35_R 39_I 1.263 0.99
66_V 70_Q 1.261 0.99
36_Q 40_D 1.259 0.99
81_V 132_I 1.257 0.99
279_I 288_I 1.252 0.99
11_I 165_A 1.249 0.99
14_S 50_I 1.248 0.99
20_T 68_V 1.243 0.98
190_A 214_V 1.24 0.98
191_K 196_D 1.233 0.98
112_E 116_E 1.229 0.98
282_Q 318_R 1.226 0.98
292_A 297_Q 1.224 0.98
273_T 303_A 1.214 0.98
260_W 271_I 1.203 0.98
312_A 315_T 1.197 0.98
2_K 15_R 1.191 0.98
77_R 129_Y 1.19 0.98
14_S 51_N 1.187 0.98
135_T 154_L 1.186 0.98
51_N 81_V 1.18 0.98
40_D 295_P 1.177 0.98
132_I 187_I 1.175 0.98
131_D 164_R 1.172 0.98
57_P 113_S 1.172 0.98
274_L 307_I 1.168 0.97
277_A 281_K 1.166 0.97
197_R 200_E 1.166 0.97
150_T 153_V 1.163 0.97
43_L 74_K 1.159 0.97
111_P 152_A 1.151 0.97
157_L 162_K 1.148 0.97
199_M 214_V 1.146 0.97
180_L 206_L 1.144 0.97
262_P 266_R 1.142 0.97
208_R 284_D 1.139 0.97
43_L 71_A 1.138 0.97
5_P 10_D 1.133 0.97
273_T 300_E 1.126 0.97
52_L 215_Q 1.126 0.97
113_S 116_E 1.122 0.97
52_L 83_E 1.115 0.96
158_K 186_D 1.113 0.96
173_A 177_R 1.113 0.96
263_L 267_Y 1.106 0.96
177_R 210_N 1.102 0.96
316_L 319_E 1.102 0.96
267_Y 310_S 1.097 0.96
282_Q 314_A 1.089 0.96
258_E 261_Q 1.087 0.96
194_I 317_M 1.085 0.96
43_L 75_L 1.078 0.95
110_S 113_S 1.076 0.95
296_E 300_E 1.059 0.95
204_L 214_V 1.056 0.95
261_Q 271_I 1.047 0.94
166_I 185_L 1.046 0.94
213_V 286_I 1.043 0.94
194_I 275_A 1.039 0.94
148_A 178_E 1.037 0.94
258_E 262_P 1.036 0.94
122_L 162_K 1.034 0.94
170_N 217_Y 1.032 0.94
205_P 208_R 1.031 0.94
157_L 160_E 1.03 0.94
187_I 215_Q 1.025 0.93
117_E 120_A 1.023 0.93
15_R 280_L 1.022 0.93
2_K 308_N 1.019 0.93
300_E 303_A 1.018 0.93
315_T 318_R 1.016 0.93
17_G 290_S 1.008 0.93
168_A 176_I 1.007 0.93
42_I 53_I 1.006 0.93
125_L 130_I 1.003 0.93
251_L 255_D 1.002 0.92
277_A 304_A 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1pyfA10.95091000.09Contact Map0.746
1pz1A20.9541000.098Contact Map0.736
3v0sA10.95711000.102Contact Map0.806
3n2tA10.96011000.104Contact Map0.712
1lqaA20.96321000.127Contact Map0.764
3n6qA80.94171000.136Contact Map0.787
3lutA10.93251000.139Contact Map0.761
3erpA20.92941000.139Contact Map0.786
3eauA10.93871000.142Contact Map0.77
1ur3M10.88961000.157Contact Map0.718
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
Page generated in 0.2743 seconds.