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OPENSEQ.org
EUTG - Ethanolamine utilization protein EutG
UniProt: P76553 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14183
Length: 395 (373)
Sequences: 4693
Seq/Len: 12.58
EUTG
Paralog alert: 0.76 [within 20: 0.07] - ratio of genomes with paralogs
Cluster includes: ADH2 AROB EUTG FUCO GLDA YBDH YQHD
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
246_P 345_E 3.716 1.00
367_Q 384_L 3.656 1.00
308_E 340_S 3.592 1.00
363_G 388_V 3.552 1.00
100_A 104_E 3.47 1.00
247_K 254_D 3.409 1.00
359_S 392_A 3.197 1.00
251_Y 254_D 3.068 1.00
93_T 173_A 2.842 1.00
283_M 391_Y 2.696 1.00
67_A 71_R 2.689 1.00
236_G 239_A 2.561 1.00
244_S 260_S 2.531 1.00
98_A 125_V 2.417 1.00
213_A 241_I 2.356 1.00
362_Y 388_V 2.354 1.00
388_V 392_A 2.285 1.00
358_T 361_H 2.278 1.00
217_A 237_A 2.224 1.00
35_G 196_A 2.216 1.00
351_R 354_D 2.21 1.00
214_L 238_I 2.196 1.00
67_A 70_T 2.19 1.00
193_L 262_L 2.177 1.00
34_P 196_A 2.163 1.00
85_C 97_A 2.141 1.00
199_E 255_L 2.128 1.00
383_S 386_Q 2.125 1.00
39_S 42_Q 2.064 1.00
365_W 391_Y 2.06 1.00
119_L 153_A 2.054 1.00
366_A 388_V 2.045 1.00
52_L 109_G 2.039 1.00
341_E 345_E 2.036 1.00
208_M 297_L 1.991 1.00
231_D 317_R 1.986 1.00
389_G 393_A 1.947 1.00
87_V 94_D 1.942 1.00
308_E 393_A 1.899 1.00
301_M 355_V 1.892 1.00
206_T 258_R 1.881 1.00
310_N 378_N 1.87 1.00
51_H 79_A 1.86 1.00
59_F 63_A 1.847 1.00
284_A 298_A 1.805 1.00
102_L 149_L 1.781 1.00
110_V 122_A 1.78 1.00
49_L 109_G 1.738 1.00
384_L 388_V 1.738 1.00
97_A 100_A 1.735 1.00
305_T 394_A 1.683 1.00
133_D 137_A 1.611 1.00
247_K 251_Y 1.597 1.00
210_G 245_L 1.59 1.00
238_I 321_I 1.583 1.00
41_G 72_S 1.583 1.00
36_S 39_S 1.581 1.00
242_G 325_L 1.578 1.00
366_A 384_L 1.569 1.00
71_R 75_V 1.566 1.00
70_T 74_T 1.565 1.00
338_A 341_E 1.562 1.00
203_S 207_A 1.55 1.00
68_G 196_A 1.547 1.00
96_C 134_S 1.544 1.00
344_A 350_K 1.542 1.00
172_D 175_S 1.538 1.00
322_G 335_A 1.537 1.00
246_P 250_G 1.527 1.00
389_G 392_A 1.513 1.00
247_K 256_A 1.501 1.00
133_D 138_E 1.486 1.00
254_D 257_A 1.483 1.00
94_D 97_A 1.483 1.00
50_K 108_D 1.472 1.00
256_A 260_S 1.461 1.00
34_P 255_L 1.46 1.00
74_T 80_M 1.459 1.00
282_A 375_L 1.455 1.00
95_V 170_I 1.455 1.00
81_T 105_S 1.439 1.00
241_I 261_M 1.433 1.00
308_E 333_R 1.425 1.00
337_N 341_E 1.42 1.00
198_T 258_R 1.419 1.00
206_T 248_A 1.414 1.00
333_R 337_N 1.413 1.00
55_M 125_V 1.412 1.00
52_L 111_I 1.403 0.99
386_Q 389_G 1.387 0.99
283_M 302_L 1.387 0.99
198_T 262_L 1.383 0.99
363_G 384_L 1.369 0.99
95_V 121_A 1.364 0.99
293_I 298_A 1.363 0.99
250_G 345_E 1.361 0.99
44_A 109_G 1.359 0.99
283_M 387_I 1.357 0.99
61_H 84_P 1.356 0.99
55_M 86_P 1.34 0.99
244_S 247_K 1.331 0.99
210_G 261_M 1.33 0.99
81_T 101_Q 1.326 0.99
206_T 252_G 1.315 0.99
58_S 62_Q 1.314 0.99
353_G 395_Q 1.31 0.99
102_L 107_C 1.291 0.99
38_S 68_G 1.288 0.99
81_T 107_C 1.283 0.99
235_I 320_Q 1.278 0.99
43_Q 46_T 1.27 0.99
101_Q 105_S 1.259 0.99
211_I 343_I 1.257 0.99
367_Q 371_E 1.251 0.99
51_H 106_G 1.24 0.98
112_A 151_L 1.237 0.98
109_G 152_I 1.234 0.98
91_C 94_D 1.218 0.98
249_V 347_G 1.216 0.98
29_V 43_Q 1.215 0.98
158_A 206_T 1.215 0.98
307_M 339_V 1.212 0.98
99_V 128_L 1.211 0.98
35_G 194_D 1.207 0.98
196_A 255_L 1.206 0.98
201_V 205_V 1.2 0.98
204_H 297_L 1.197 0.98
112_A 122_A 1.191 0.98
96_C 100_A 1.184 0.98
309_F 386_Q 1.184 0.98
152_I 190_V 1.169 0.97
51_H 56_A 1.169 0.97
237_A 268_A 1.168 0.97
101_Q 104_E 1.167 0.97
87_V 91_C 1.165 0.97
305_T 393_A 1.16 0.97
69_L 113_F 1.154 0.97
100_A 103_R 1.153 0.97
112_A 119_L 1.152 0.97
220_A 271_A 1.146 0.97
364_A 367_Q 1.145 0.97
203_S 250_G 1.144 0.97
279_L 382_A 1.142 0.97
92_I 96_C 1.129 0.97
102_L 129_V 1.126 0.97
58_S 84_P 1.126 0.97
231_D 234_A 1.125 0.97
30_T 266_C 1.124 0.97
203_S 249_V 1.122 0.97
364_A 368_A 1.119 0.96
196_A 199_E 1.118 0.96
70_T 80_M 1.117 0.96
34_P 199_E 1.115 0.96
217_A 268_A 1.113 0.96
126_T 148_R 1.107 0.96
235_I 324_A 1.106 0.96
53_F 107_C 1.105 0.96
218_I 238_I 1.103 0.96
311_R 333_R 1.099 0.96
122_A 151_L 1.098 0.96
312_M 380_R 1.097 0.96
44_A 152_I 1.096 0.96
89_E 292_H 1.096 0.96
31_L 43_Q 1.093 0.96
272_F 277_L 1.092 0.96
244_S 257_A 1.085 0.96
243_K 260_S 1.08 0.95
220_A 234_A 1.08 0.95
110_V 126_T 1.079 0.95
34_P 259_E 1.07 0.95
211_I 348_I 1.058 0.95
195_A 259_E 1.058 0.95
207_A 249_V 1.057 0.95
362_Y 392_A 1.057 0.95
385_E 388_V 1.056 0.95
220_A 231_D 1.056 0.95
232_S 236_G 1.051 0.94
40_C 154_I 1.048 0.94
71_R 74_T 1.046 0.94
244_S 256_A 1.037 0.94
321_I 335_A 1.036 0.94
361_H 364_A 1.036 0.94
91_C 292_H 1.035 0.94
280_C 299_N 1.023 0.93
215_T 303_L 1.019 0.93
112_A 153_A 1.011 0.93
51_H 81_T 1.004 0.93
305_T 308_E 1 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3bfjA200.95951000.161Contact Map0.836
3ox4A40.95441000.161Contact Map0.852
1rrmA20.94941000.174Contact Map0.797
4fr2A10.98731000.176Contact Map0.58
1vljA20.98231000.187Contact Map0.744
1oj7A40.98231000.202Contact Map0.705
3zdrA10.98731000.21Contact Map0.798
1o2dA20.92911000.23Contact Map0.698
3jzdA40.88861000.256Contact Map0.725
3hl0A20.87591000.257Contact Map0.738
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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