| UniProt: | P31453 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11711 | ||
| Length: | 238 (231) | ||
| Sequences: | 3978 | ||
| Seq/Len: | 17.22 |
| YIDP
Paralog alert: 0.83 [within 20: 0.08] - ratio of genomes with paralogs Cluster includes: FRLR MNGR PHNF YEGW YIDP YIHL |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 20_T | 23_S | 4.457 | 1.00 | |
| 181_A | 197_L | 3.231 | 1.00 | |
| 185_L | 218_F | 3.182 | 1.00 | |
| 13_R | 34_E | 3.028 | 1.00 | |
| 9_R | 35_F | 2.876 | 1.00 | |
| 13_R | 18_D | 2.862 | 1.00 | |
| 11_R | 52_W | 2.764 | 1.00 | |
| 58_R | 61_S | 2.61 | 1.00 | |
| 182_D | 185_L | 2.592 | 1.00 | |
| 94_Q | 127_F | 2.498 | 1.00 | |
| 180_L | 196_P | 2.473 | 1.00 | |
| 6_I | 37_V | 2.467 | 1.00 | |
| 46_I | 55_V | 2.287 | 1.00 | |
| 24_L | 64_Y | 2.26 | 1.00 | |
| 107_I | 139_Y | 2.221 | 1.00 | |
| 7_A | 48_L | 2.188 | 1.00 | |
| 55_V | 63_T | 2.186 | 1.00 | |
| 7_A | 52_W | 2.101 | 1.00 | |
| 123_R | 137_D | 2.06 | 1.00 | |
| 92_T | 127_F | 2.035 | 1.00 | |
| 121_F | 137_D | 1.981 | 1.00 | |
| 12_I | 16_S | 1.972 | 1.00 | |
| 50_V | 55_V | 1.954 | 1.00 | |
| 104_P | 107_I | 1.936 | 1.00 | |
| 61_S | 64_Y | 1.918 | 1.00 | |
| 114_Q | 117_E | 1.854 | 1.00 | |
| 123_R | 184_L | 1.787 | 1.00 | |
| 11_R | 54_L | 1.785 | 1.00 | |
| 92_T | 130_G | 1.726 | 1.00 | |
| 135_L | 185_L | 1.723 | 1.00 | |
| 96_L | 125_V | 1.718 | 1.00 | |
| 117_E | 143_K | 1.707 | 1.00 | |
| 28_E | 39_R | 1.684 | 1.00 | |
| 89_K | 129_E | 1.682 | 1.00 | |
| 2_I | 5_S | 1.617 | 1.00 | |
| 177_T | 199_R | 1.616 | 1.00 | |
| 179_V | 199_R | 1.611 | 1.00 | |
| 100_I | 118_Q | 1.601 | 1.00 | |
| 101_M | 121_F | 1.595 | 1.00 | |
| 97_I | 123_R | 1.58 | 1.00 | |
| 46_I | 50_V | 1.579 | 1.00 | |
| 25_L | 55_V | 1.551 | 1.00 | |
| 175_S | 225_Q | 1.544 | 1.00 | |
| 7_A | 11_R | 1.539 | 1.00 | |
| 131_K | 223_E | 1.536 | 1.00 | |
| 9_R | 13_R | 1.52 | 1.00 | |
| 56_V | 66_V | 1.514 | 1.00 | |
| 174_E | 202_S | 1.514 | 1.00 | |
| 50_V | 57_R | 1.511 | 1.00 | |
| 101_M | 107_I | 1.506 | 1.00 | |
| 100_I | 142_V | 1.494 | 1.00 | |
| 181_A | 194_H | 1.492 | 1.00 | |
| 191_V | 197_L | 1.484 | 1.00 | |
| 173_Y | 229_H | 1.476 | 1.00 | |
| 93_S | 126_R | 1.471 | 1.00 | |
| 178_P | 198_L | 1.458 | 1.00 | |
| 177_T | 225_Q | 1.457 | 1.00 | |
| 6_I | 42_I | 1.426 | 1.00 | |
| 103_A | 119_I | 1.424 | 1.00 | |
| 135_L | 188_Q | 1.414 | 1.00 | |
| 97_I | 121_F | 1.404 | 0.99 | |
| 159_E | 163_Q | 1.396 | 0.99 | |
| 44_K | 47_D | 1.385 | 0.99 | |
| 179_V | 185_L | 1.37 | 0.99 | |
| 108_A | 113_I | 1.368 | 0.99 | |
| 28_E | 43_R | 1.353 | 0.99 | |
| 171_G | 229_H | 1.339 | 0.99 | |
| 167_I | 206_S | 1.332 | 0.99 | |
| 181_A | 195_T | 1.329 | 0.99 | |
| 113_I | 117_E | 1.323 | 0.99 | |
| 158_F | 204_S | 1.318 | 0.99 | |
| 206_S | 210_E | 1.316 | 0.99 | |
| 6_I | 9_R | 1.304 | 0.99 | |
| 203_L | 211_F | 1.296 | 0.99 | |
| 111_L | 119_I | 1.291 | 0.99 | |
| 99_E | 121_F | 1.291 | 0.99 | |
| 44_K | 48_L | 1.284 | 0.99 | |
| 158_F | 213_N | 1.278 | 0.99 | |
| 103_A | 108_A | 1.277 | 0.99 | |
| 13_R | 19_F | 1.276 | 0.99 | |
| 206_S | 212_L | 1.268 | 0.99 | |
| 143_K | 210_E | 1.263 | 0.99 | |
| 145_F | 161_I | 1.26 | 0.99 | |
| 47_D | 51_A | 1.258 | 0.99 | |
| 11_R | 15_N | 1.256 | 0.99 | |
| 84_L | 128_V | 1.256 | 0.99 | |
| 57_R | 63_T | 1.243 | 0.98 | |
| 111_L | 211_F | 1.241 | 0.98 | |
| 6_I | 35_F | 1.239 | 0.98 | |
| 181_A | 191_V | 1.237 | 0.98 | |
| 192_A | 195_T | 1.233 | 0.98 | |
| 175_S | 227_E | 1.227 | 0.98 | |
| 98_F | 149_S | 1.227 | 0.98 | |
| 140_M | 157_K | 1.187 | 0.98 | |
| 199_R | 216_V | 1.182 | 0.98 | |
| 197_L | 218_F | 1.174 | 0.98 | |
| 162_E | 168_L | 1.161 | 0.97 | |
| 37_V | 42_I | 1.161 | 0.97 | |
| 179_V | 197_L | 1.148 | 0.97 | |
| 103_A | 117_E | 1.134 | 0.97 | |
| 127_F | 130_G | 1.131 | 0.97 | |
| 113_I | 119_I | 1.124 | 0.97 | |
| 94_Q | 125_V | 1.116 | 0.96 | |
| 14_L | 65_L | 1.101 | 0.96 | |
| 13_R | 35_F | 1.094 | 0.96 | |
| 186_A | 194_H | 1.093 | 0.96 | |
| 180_L | 195_T | 1.081 | 0.95 | |
| 3_Y | 48_L | 1.08 | 0.95 | |
| 80_L | 84_L | 1.077 | 0.95 | |
| 103_A | 113_I | 1.074 | 0.95 | |
| 4_K | 8_E | 1.065 | 0.95 | |
| 19_F | 23_S | 1.036 | 0.94 | |
| 108_A | 115_I | 1.033 | 0.94 | |
| 138_S | 213_N | 1.027 | 0.94 | |
| 47_D | 57_R | 1.025 | 0.93 | |
| 31_L | 42_I | 1.024 | 0.93 | |
| 21_L | 67_R | 1.021 | 0.93 | |
| 108_A | 116_N | 1.011 | 0.93 | |
| 201_T | 216_V | 1.008 | 0.93 | |
| 27_G | 30_K | 1.008 | 0.93 | |
| 102_P | 118_Q | 1.002 | 0.92 | |
| 103_A | 116_N | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2wv0A | 10 | 0.9832 | 100 | 0.127 | Contact Map | 0.875 |
| 3f8mA | 2 | 0.979 | 100 | 0.155 | Contact Map | 0.762 |
| 2ra5A | 1 | 0.9706 | 100 | 0.163 | Contact Map | 0.683 |
| 3edpA | 2 | 0.9454 | 100 | 0.166 | Contact Map | 0.702 |
| 3eetA | 2 | 0.9664 | 100 | 0.178 | Contact Map | 0.752 |
| 3bwgA | 3 | 0.979 | 100 | 0.185 | Contact Map | 0.845 |
| 3f8lA | 4 | 0.8319 | 100 | 0.396 | Contact Map | 0.788 |
| 3hfiA | 1 | 0.7059 | 100 | 0.5 | Contact Map | 0.78 |
| 2ikkA | 2 | 0.7101 | 100 | 0.511 | Contact Map | 0.878 |
| 3cnvA | 4 | 0.6555 | 100 | 0.514 | Contact Map | 0.824 |
Sequence Conservation (Image Generated using WebLogo v3)