| UniProt: | P0ACM9 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11838 | ||
| Length: | 236 (232) | ||
| Sequences: | 3981 | ||
| Seq/Len: | 17.16 |
| YIHL
Paralog alert: 0.83 [within 20: 0.08] - ratio of genomes with paralogs Cluster includes: FRLR MNGR PHNF YEGW YIDP YIHL |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 25_T | 28_G | 4.48 | 1.00 | |
| 191_I | 224_Y | 3.229 | 1.00 | |
| 187_M | 203_A | 3.111 | 1.00 | |
| 18_W | 39_L | 3.042 | 1.00 | |
| 18_W | 23_I | 2.891 | 1.00 | |
| 14_K | 40_L | 2.854 | 1.00 | |
| 16_D | 57_E | 2.797 | 1.00 | |
| 188_P | 191_I | 2.626 | 1.00 | |
| 63_K | 66_K | 2.612 | 1.00 | |
| 11_A | 42_I | 2.492 | 1.00 | |
| 99_G | 133_A | 2.48 | 1.00 | |
| 186_R | 202_P | 2.389 | 1.00 | |
| 51_L | 60_I | 2.239 | 1.00 | |
| 29_K | 69_F | 2.218 | 1.00 | |
| 113_L | 145_Y | 2.193 | 1.00 | |
| 102_E | 105_R | 2.171 | 1.00 | |
| 60_I | 68_W | 2.161 | 1.00 | |
| 12_K | 53_N | 2.156 | 1.00 | |
| 12_K | 57_E | 2.075 | 1.00 | |
| 97_S | 133_A | 2.044 | 1.00 | |
| 129_T | 143_E | 2.022 | 1.00 | |
| 17_R | 21_D | 2.005 | 1.00 | |
| 55_E | 60_I | 1.954 | 1.00 | |
| 110_P | 113_L | 1.95 | 1.00 | |
| 127_R | 143_E | 1.941 | 1.00 | |
| 66_K | 69_F | 1.921 | 1.00 | |
| 120_T | 123_T | 1.842 | 1.00 | |
| 129_T | 190_D | 1.816 | 1.00 | |
| 179_K | 235_N | 1.756 | 1.00 | |
| 97_S | 136_G | 1.755 | 1.00 | |
| 33_E | 44_R | 1.737 | 1.00 | |
| 16_D | 59_K | 1.734 | 1.00 | |
| 141_Y | 191_I | 1.707 | 1.00 | |
| 94_R | 135_E | 1.689 | 1.00 | |
| 7_T | 10_N | 1.67 | 1.00 | |
| 181_I | 231_D | 1.643 | 1.00 | |
| 123_T | 149_E | 1.631 | 1.00 | |
| 101_T | 131_W | 1.631 | 1.00 | |
| 183_K | 205_L | 1.604 | 1.00 | |
| 102_E | 129_T | 1.598 | 1.00 | |
| 106_T | 124_E | 1.588 | 1.00 | |
| 107_S | 127_R | 1.587 | 1.00 | |
| 137_H | 229_A | 1.581 | 1.00 | |
| 183_K | 231_D | 1.569 | 1.00 | |
| 30_L | 60_I | 1.564 | 1.00 | |
| 185_V | 205_L | 1.55 | 1.00 | |
| 107_S | 113_L | 1.548 | 1.00 | |
| 51_L | 55_E | 1.535 | 1.00 | |
| 12_K | 16_D | 1.523 | 1.00 | |
| 98_W | 132_G | 1.505 | 1.00 | |
| 61_F | 71_T | 1.499 | 1.00 | |
| 197_G | 203_A | 1.497 | 1.00 | |
| 187_M | 200_G | 1.486 | 1.00 | |
| 14_K | 18_W | 1.474 | 1.00 | |
| 106_T | 148_P | 1.465 | 1.00 | |
| 181_I | 233_I | 1.451 | 1.00 | |
| 55_E | 62_R | 1.444 | 1.00 | |
| 184_P | 204_I | 1.425 | 1.00 | |
| 109_I | 125_L | 1.423 | 1.00 | |
| 177_V | 235_N | 1.415 | 1.00 | |
| 180_L | 208_K | 1.413 | 1.00 | |
| 141_Y | 194_Y | 1.402 | 0.99 | |
| 114_A | 119_V | 1.398 | 0.99 | |
| 102_E | 127_R | 1.387 | 0.99 | |
| 173_K | 212_D | 1.38 | 0.99 | |
| 11_A | 47_L | 1.362 | 0.99 | |
| 49_Q | 52_L | 1.354 | 0.99 | |
| 165_A | 169_K | 1.343 | 0.99 | |
| 33_E | 48_R | 1.343 | 0.99 | |
| 212_D | 216_N | 1.339 | 0.99 | |
| 187_M | 201_M | 1.332 | 0.99 | |
| 185_V | 191_I | 1.322 | 0.99 | |
| 119_V | 123_T | 1.311 | 0.99 | |
| 109_I | 114_A | 1.311 | 0.99 | |
| 117_I | 125_L | 1.296 | 0.99 | |
| 209_H | 217_I | 1.295 | 0.99 | |
| 18_W | 24_T | 1.295 | 0.99 | |
| 11_A | 14_K | 1.295 | 0.99 | |
| 52_L | 56_A | 1.29 | 0.99 | |
| 62_R | 68_W | 1.29 | 0.99 | |
| 49_Q | 53_N | 1.288 | 0.99 | |
| 104_N | 155_I | 1.271 | 0.99 | |
| 164_S | 210_R | 1.269 | 0.99 | |
| 11_A | 40_L | 1.266 | 0.99 | |
| 198_S | 201_M | 1.257 | 0.99 | |
| 212_D | 218_V | 1.248 | 0.99 | |
| 205_L | 222_I | 1.247 | 0.99 | |
| 151_A | 167_W | 1.246 | 0.98 | |
| 89_A | 134_L | 1.244 | 0.98 | |
| 203_A | 224_Y | 1.239 | 0.98 | |
| 164_S | 219_Q | 1.232 | 0.98 | |
| 117_I | 217_I | 1.23 | 0.98 | |
| 105_R | 127_R | 1.228 | 0.98 | |
| 187_M | 197_G | 1.221 | 0.98 | |
| 16_D | 20_K | 1.217 | 0.98 | |
| 8_V | 53_N | 1.184 | 0.98 | |
| 179_K | 233_I | 1.179 | 0.98 | |
| 149_E | 216_N | 1.142 | 0.97 | |
| 192_S | 200_G | 1.141 | 0.97 | |
| 185_V | 203_A | 1.136 | 0.97 | |
| 18_W | 40_L | 1.136 | 0.97 | |
| 168_E | 174_E | 1.136 | 0.97 | |
| 42_I | 47_L | 1.129 | 0.97 | |
| 133_A | 136_G | 1.118 | 0.96 | |
| 119_V | 125_L | 1.09 | 0.96 | |
| 109_I | 123_T | 1.083 | 0.96 | |
| 85_F | 89_A | 1.071 | 0.95 | |
| 146_I | 163_F | 1.066 | 0.95 | |
| 99_G | 131_W | 1.057 | 0.95 | |
| 9_E | 13_E | 1.056 | 0.95 | |
| 109_I | 119_V | 1.048 | 0.94 | |
| 207_E | 222_I | 1.043 | 0.94 | |
| 19_L | 70_V | 1.042 | 0.94 | |
| 186_R | 201_M | 1.038 | 0.94 | |
| 32_S | 35_E | 1.031 | 0.94 | |
| 52_L | 62_R | 1.029 | 0.94 | |
| 26_P | 72_Q | 1.022 | 0.93 | |
| 74_R | 183_K | 1.018 | 0.93 | |
| 104_N | 126_Y | 1.018 | 0.93 | |
| 24_T | 28_G | 1.015 | 0.93 | |
| 36_L | 47_L | 1.015 | 0.93 | |
| 144_T | 219_Q | 1.014 | 0.93 | |
| 109_I | 122_S | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2wv0A | 10 | 0.9958 | 100 | 0.083 | Contact Map | 0.879 |
| 3f8mA | 2 | 0.9746 | 100 | 0.109 | Contact Map | 0.761 |
| 3edpA | 2 | 0.9746 | 100 | 0.11 | Contact Map | 0.692 |
| 2ra5A | 1 | 0.9831 | 100 | 0.115 | Contact Map | 0.673 |
| 3eetA | 2 | 0.9831 | 100 | 0.13 | Contact Map | 0.739 |
| 3bwgA | 3 | 0.9831 | 100 | 0.138 | Contact Map | 0.837 |
| 3f8lA | 4 | 0.8051 | 100 | 0.362 | Contact Map | 0.789 |
| 3hfiA | 1 | 0.6864 | 100 | 0.482 | Contact Map | 0.767 |
| 3cnvA | 4 | 0.6568 | 100 | 0.486 | Contact Map | 0.822 |
| 2ikkA | 2 | 0.7034 | 100 | 0.486 | Contact Map | 0.874 |
Sequence Conservation (Image Generated using WebLogo v3)