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OPENSEQ.org

RUTC - Putative aminoacrylate peracid reductase RutC
UniProt: P0AFQ5 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13857
Length: 128 (126)
Sequences: 4501
Seq/Len: 35.72

RUTC
Paralog alert: 0.59 [within 20: 0.10] - ratio of genomes with paralogs
Cluster includes: RIDA RUTC TDCF YJGH YOAB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
53_R 95_E 3.455 1.00
60_R 70_M 2.843 1.00
75_F 121_A 2.715 1.00
47_D 50_A 2.644 1.00
49_K 91_E 2.593 1.00
49_K 88_A 2.384 1.00
68_G 72_D 2.381 1.00
68_G 126_I 2.298 1.00
60_R 64_E 2.188 1.00
53_R 57_E 2.163 1.00
63_I 124_A 2.126 1.00
108_Q 111_L 2.12 1.00
79_F 107_I 2.031 1.00
51_Q 117_L 1.958 1.00
23_L 126_I 1.95 1.00
78_I 89_I 1.909 1.00
57_E 96_F 1.896 1.00
34_L 116_A 1.876 1.00
76_N 122_T 1.775 1.00
24_A 74_T 1.725 1.00
59_I 122_T 1.722 1.00
28_V 68_G 1.718 1.00
54_H 58_T 1.711 1.00
37_D 40_N 1.648 1.00
4_S 23_L 1.636 1.00
85_N 117_L 1.604 1.00
57_E 60_R 1.584 1.00
24_A 125_H 1.57 1.00
48_P 52_T 1.446 1.00
53_R 96_F 1.397 0.99
35_A 116_A 1.389 0.99
28_V 66_A 1.386 0.99
69_T 72_D 1.382 0.99
80_I 106_C 1.347 0.99
105_F 121_A 1.339 0.99
35_A 55_V 1.337 0.99
111_L 115_D 1.335 0.99
54_H 57_E 1.334 0.99
81_T 85_N 1.315 0.99
27_V 125_H 1.309 0.99
88_A 91_E 1.278 0.99
83_W 108_Q 1.274 0.99
43_L 116_A 1.263 0.99
23_L 26_G 1.262 0.99
29_Y 123_I 1.26 0.99
73_V 97_F 1.23 0.98
80_I 89_I 1.226 0.98
90_N 104_R 1.197 0.98
79_F 105_F 1.18 0.98
85_N 88_A 1.176 0.98
73_V 122_T 1.162 0.97
49_K 92_I 1.122 0.97
70_M 73_V 1.118 0.96
92_I 95_E 1.115 0.96
45_A 50_A 1.109 0.96
63_I 68_G 1.108 0.96
93_Y 104_R 1.104 0.96
8_P 20_P 1.101 0.96
77_S 121_A 1.099 0.96
30_V 62_V 1.086 0.96
23_L 28_V 1.069 0.95
37_D 44_F 1.065 0.95
49_K 53_R 1.058 0.95
52_T 89_I 1.052 0.95
64_E 69_T 1.048 0.94
21_G 62_V 1.041 0.94
56_L 96_F 1.034 0.94
60_R 96_F 1.012 0.93
81_T 117_L 1.011 0.93
42_V 114_P 1.002 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3v4dA611000.066Contact Map0.892
1xrgA30.98441000.073Contact Map0.874
1qahA211000.077Contact Map0.663
3r0pA60.98441000.081Contact Map0.863
3k0tA30.98441000.082Contact Map0.835
3m1xA10.98441000.086Contact Map0.657
3quwA10.99221000.087Contact Map0.715
2dyyA120.98441000.088Contact Map0.961
1jd1A60.99221000.096Contact Map0.877
3vczA30.97661000.097Contact Map0.896

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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