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OPENSEQ.org

YOAB - RutC family protein YoaB
UniProt: P0AEB7 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13514
Length: 114 (112)
Sequences: 4343
Seq/Len: 38.78

YOAB
Paralog alert: 0.59 [within 20: 0.09] - ratio of genomes with paralogs
Cluster includes: RIDA RUTC TDCF YJGH YOAB
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
40_A 82_A 3.452 1.00
47_D 57_K 2.95 1.00
34_D 37_E 2.718 1.00
62_D 109_K 2.696 1.00
36_F 78_K 2.557 1.00
55_S 59_S 2.412 1.00
36_F 75_A 2.325 1.00
40_A 44_A 2.261 1.00
47_D 51_E 2.236 1.00
50_L 112_A 2.074 1.00
38_Q 105_K 2.026 1.00
66_F 95_V 1.986 1.00
27_V 104_Y 1.953 1.00
65_I 76_M 1.94 1.00
44_A 83_W 1.899 1.00
55_S 114_V 1.808 1.00
41_N 45_Q 1.8 1.00
18_H 61_L 1.787 1.00
72_D 105_K 1.7 1.00
22_L 55_S 1.686 1.00
63_A 110_I 1.682 1.00
18_H 113_A 1.674 1.00
44_A 47_D 1.655 1.00
46_I 110_I 1.611 1.00
17_I 114_V 1.599 1.00
96_Q 99_L 1.59 1.00
99_L 103_K 1.573 1.00
56_N 59_S 1.455 1.00
28_P 104_Y 1.396 0.99
93_C 109_K 1.386 0.99
40_A 83_W 1.376 0.99
22_L 53_Q 1.361 0.99
35_A 39_T 1.356 0.99
67_L 94_T 1.35 0.99
21_T 113_A 1.348 0.99
68_A 72_D 1.323 0.99
75_A 78_K 1.312 0.99
41_N 44_A 1.31 0.99
28_P 42_T 1.277 0.99
60_I 84_V 1.262 0.99
23_Y 111_V 1.253 0.99
77_N 92_R 1.247 0.99
70_K 96_Q 1.235 0.98
67_L 76_M 1.23 0.98
7_D 52_K 1.206 0.98
17_I 20_N 1.175 0.98
66_F 93_C 1.162 0.97
36_F 79_A 1.161 0.97
72_D 75_A 1.156 0.97
79_A 82_A 1.143 0.97
60_I 110_I 1.139 0.97
64_T 109_K 1.134 0.97
50_L 55_S 1.133 0.97
80_W 92_R 1.1 0.96
69_D 72_D 1.084 0.96
17_I 22_L 1.066 0.95
68_A 105_K 1.06 0.95
51_E 56_N 1.055 0.95
32_D 37_E 1.05 0.94
57_K 60_I 1.023 0.93
47_D 83_W 1.012 0.93
24_Y 49_V 1.007 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3gtzA30.99121000.045Contact Map0.792
3k12A60.99121000.057Contact Map0.854
3kjjA120.99121000.079Contact Map0.753
1xrgA30.99121000.089Contact Map0.866
3v4dA60.99121000.094Contact Map0.913
3m1xA10.99121000.102Contact Map0.637
3quwA10.99121000.106Contact Map0.721
3r0pA60.99121000.111Contact Map0.859
3k0tA30.99121000.112Contact Map0.826
3lmeA1211000.115Contact Map0.877

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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