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OPENSEQ.org

GLGA - Glycogen synthase
UniProt: P0A6U8 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10377
Length: 477 (466)
Sequences: 6628
Seq/Len: 14.22

GLGA
Paralog alert: 0.64 [within 20: 0.10] - ratio of genomes with paralogs
Cluster includes: GLGA RFAB RFAG WBBK WCAC WCAI WCAL
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
2_Q 36_D 4.451 1.00
296_A 367_A 4.087 1.00
134_H 473_Y 3.893 1.00
323_Q 350_G 3.671 1.00
207_H 242_S 3.347 1.00
35_V 470_R 3.164 1.00
292_V 323_Q 3.088 1.00
3_V 35_V 3.08 1.00
33_D 467_K 2.91 1.00
316_G 429_W 2.834 1.00
395_V 422_V 2.738 1.00
33_D 470_R 2.709 1.00
314_L 324_L 2.644 1.00
293_P 439_F 2.593 1.00
424_E 430_S 2.57 1.00
38_R 80_Y 2.57 1.00
4_L 40_L 2.549 1.00
38_R 130_P 2.513 1.00
397_R 424_E 2.493 1.00
405_V 420_G 2.418 1.00
134_H 159_T 2.405 1.00
216_A 220_T 2.391 1.00
444_R 447_L 2.381 1.00
335_Q 339_L 2.377 1.00
370_I 386_G 2.325 1.00
427_N 430_S 2.247 1.00
38_R 128_W 2.236 1.00
312_E 341_A 2.213 1.00
316_G 432_L 2.182 1.00
294_L 325_A 2.181 1.00
1_M 35_V 2.164 1.00
308_D 375_R 2.163 1.00
421_F 434_A 2.062 1.00
242_S 475_R 2.061 1.00
428_A 432_L 2.016 1.00
283_A 362_R 2.01 1.00
158_F 205_A 2.009 1.00
310_V 371_L 1.999 1.00
295_F 369_V 1.996 1.00
301_L 326_L 1.986 1.00
437_R 447_L 1.974 1.00
295_F 435_I 1.954 1.00
464_V 468_S 1.933 1.00
450_F 454_Q 1.904 1.00
29_A 32_A 1.895 1.00
317_L 436_R 1.864 1.00
294_L 366_G 1.86 1.00
370_I 391_T 1.857 1.00
369_V 394_L 1.823 1.00
424_E 427_N 1.823 1.00
336_E 340_A 1.817 1.00
5_H 27_P 1.811 1.00
452_Q 455_A 1.811 1.00
390_G 456_M 1.807 1.00
213_P 217_R 1.789 1.00
318_L 348_Q 1.787 1.00
317_L 322_G 1.78 1.00
313_A 431_L 1.78 1.00
448_W 452_Q 1.763 1.00
312_E 428_A 1.762 1.00
5_H 30_Q 1.75 1.00
447_L 450_F 1.722 1.00
207_H 475_R 1.708 1.00
397_R 402_A 1.702 1.00
247_G 462_W 1.696 1.00
342_A 351_V 1.693 1.00
38_R 78_G 1.692 1.00
29_A 466_A 1.69 1.00
383_Q 401_L 1.69 1.00
392_L 455_A 1.685 1.00
244_V 472_L 1.685 1.00
5_H 136_H 1.679 1.00
470_R 474_Y 1.678 1.00
449_R 453_R 1.658 1.00
464_V 467_K 1.658 1.00
430_S 434_A 1.646 1.00
406_S 418_A 1.634 1.00
468_S 471_E 1.621 1.00
29_A 463_Q 1.621 1.00
136_H 161_H 1.616 1.00
434_A 437_R 1.607 1.00
4_L 130_P 1.603 1.00
207_H 472_L 1.6 1.00
217_R 220_T 1.598 1.00
135_A 158_F 1.596 1.00
367_A 391_T 1.596 1.00
333_V 339_L 1.59 1.00
327_L 363_I 1.584 1.00
229_E 233_Q 1.576 1.00
295_F 324_L 1.573 1.00
377_E 380_G 1.566 1.00
211_V 246_N 1.564 1.00
298_V 364_M 1.557 1.00
209_T 469_Y 1.539 1.00
394_L 435_I 1.533 1.00
297_V 307_L 1.521 1.00
217_R 221_E 1.519 1.00
310_V 324_L 1.513 1.00
216_A 241_L 1.504 1.00
293_P 369_V 1.484 1.00
369_V 438_A 1.48 1.00
209_T 472_L 1.474 1.00
26_L 469_Y 1.471 1.00
316_G 319_E 1.469 1.00
148_A 206_D 1.464 1.00
296_A 364_M 1.463 1.00
31_I 37_A 1.462 1.00
244_V 469_Y 1.452 1.00
445_P 448_W 1.45 1.00
395_V 405_V 1.449 1.00
350_G 353_I 1.447 1.00
295_F 371_L 1.417 1.00
438_A 448_W 1.414 1.00
294_L 323_Q 1.413 1.00
33_D 466_A 1.412 1.00
135_A 156_S 1.411 1.00
340_A 344_E 1.41 1.00
394_L 434_A 1.409 1.00
216_A 243_G 1.403 0.99
306_G 309_L 1.382 0.99
161_H 381_L 1.381 0.99
406_S 419_S 1.375 0.99
305_K 374_S 1.368 0.99
316_G 428_A 1.365 0.99
356_H 359_F 1.359 0.99
235_R 238_E 1.357 0.99
314_L 322_G 1.357 0.99
32_A 463_Q 1.351 0.99
213_P 243_G 1.346 0.99
313_A 432_L 1.333 0.99
338_F 351_V 1.332 0.99
386_G 391_T 1.331 0.99
155_K 206_D 1.328 0.99
249_D 253_W 1.325 0.99
300_R 305_K 1.325 0.99
213_P 216_A 1.32 0.99
453_R 457_A 1.319 0.99
317_L 435_I 1.313 0.99
269_T 272_D 1.311 0.99
454_Q 457_A 1.31 0.99
298_V 327_L 1.305 0.99
220_T 236_H 1.304 0.99
158_F 198_L 1.3 0.99
374_S 377_E 1.299 0.99
423_F 434_A 1.296 0.99
280_L 366_G 1.295 0.99
338_F 343_A 1.291 0.99
338_F 342_A 1.269 0.99
372_V 382_T 1.265 0.99
213_P 403_D 1.26 0.99
391_T 452_Q 1.26 0.99
315_P 318_L 1.253 0.99
210_A 241_L 1.236 0.98
430_S 433_R 1.232 0.98
22_V 161_H 1.23 0.98
132_V 473_Y 1.228 0.98
136_H 159_T 1.224 0.98
157_V 476_L 1.221 0.98
292_V 321_G 1.217 0.98
253_W 361_H 1.215 0.98
245_L 460_F 1.213 0.98
324_L 349_V 1.209 0.98
423_F 430_S 1.208 0.98
461_S 464_V 1.207 0.98
359_F 362_R 1.202 0.98
17_G 20_A 1.201 0.98
279_Q 282_I 1.187 0.98
471_E 474_Y 1.181 0.98
28_A 75_N 1.18 0.98
421_F 437_R 1.173 0.98
437_R 444_R 1.173 0.98
364_M 382_T 1.172 0.98
296_A 363_I 1.166 0.97
157_V 209_T 1.166 0.97
162_N 378_P 1.164 0.97
395_V 401_L 1.162 0.97
23_I 136_H 1.159 0.97
156_S 205_A 1.155 0.97
159_T 473_Y 1.151 0.97
209_T 244_V 1.148 0.97
305_K 377_E 1.14 0.97
24_G 28_A 1.135 0.97
294_L 368_D 1.131 0.97
298_V 360_S 1.124 0.97
1_M 131_D 1.116 0.96
445_P 449_R 1.116 0.96
282_I 288_V 1.114 0.96
336_E 339_L 1.111 0.96
22_V 246_N 1.108 0.96
467_K 471_E 1.103 0.96
256_E 266_T 1.102 0.96
132_V 477_K 1.101 0.96
253_W 389_Y 1.097 0.96
309_L 426_S 1.095 0.96
222_P 229_E 1.093 0.96
300_R 304_Q 1.085 0.96
315_P 345_Y 1.084 0.96
31_I 76_G 1.084 0.96
22_V 136_H 1.082 0.96
141_G 158_F 1.081 0.95
372_V 383_Q 1.079 0.95
266_T 269_T 1.077 0.95
249_D 252_I 1.075 0.95
418_A 454_Q 1.074 0.95
210_A 219_I 1.074 0.95
165_Y 302_T 1.071 0.95
365_G 389_Y 1.062 0.95
369_V 435_I 1.059 0.95
250_E 461_S 1.056 0.95
380_G 383_Q 1.054 0.95
429_W 433_R 1.05 0.94
295_F 322_G 1.05 0.94
296_A 327_L 1.049 0.94
444_R 450_F 1.047 0.94
450_F 453_R 1.047 0.94
462_W 465_A 1.046 0.94
440_V 444_R 1.045 0.94
451_V 454_Q 1.044 0.94
396_R 423_F 1.041 0.94
291_K 321_G 1.039 0.94
293_P 368_D 1.038 0.94
305_K 382_T 1.036 0.94
7_C 23_I 1.033 0.94
297_V 310_V 1.032 0.94
340_A 343_A 1.031 0.94
71_F 78_G 1.028 0.94
452_Q 456_M 1.026 0.94
309_L 431_L 1.02 0.93
278_R 282_I 1.016 0.93
405_V 419_S 1.011 0.93
27_P 37_A 1.01 0.93
27_P 39_V 1.007 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2qzsA111000.19Contact Map0.763
1rzuA20.97271000.194Contact Map0.74
4hlnA10.99161000.254Contact Map0.716
3vueA10.96231000.274Contact Map0.751
3froA30.87421000.319Contact Map0.793
2r60A10.8471000.329Contact Map0.724
3c48A20.81761000.348Contact Map0.823
3s28A80.89731000.356Contact Map0.577
3nb0A40.92031000.385Contact Map0.561
3okpA10.75681000.387Contact Map0.734

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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