OPENSEQ.org -1516281329- GREMLIN Submission

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mep50

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Coupling matrix for [L:0095] and [V:0133]

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
A	0.2	0.6	0	0.2	-0.1	-0.4	0.3	0.6	-0.2	-0.8	-0.3	0	-0.1	-0.7	-0.3	0.1	0.1	1	-0.2	-0.1
F	0.1	-0.1	0.4	0.5	0.5	-0.4	-0.1	0.1	0.3	-0.8	0	-0.7	-0.1	0.1	-0.5	0.1	0.6	-0.1	0.5	0.3
I	0.1	0.5	0.6	0.3	0.4	0	0.3	0.1	-0.3	-0.7	-0.1	0.2	-0.2	-0.2	0	0	0.1	-0.1	0.1	0.2
L	0.1	0.3	0.3	0.5	0.4	0.1	0.8	-0.2	-0.6	0.5	-0.1	-0.3	0	0.1	0.4	0	-0.1	-0.8	0.1	0.2
V	0.1	0.3	0.2	0.3	0.3	-0.1	0.3	-0.1	0.4	0.4	0	-0.1	-0.2	0.1	-0.1	-0.2	0.1	-0.5	-0.1	0.1
M	0.1	0.6	0.5	0.1	0.2	0.4	0.1	0	-0.1	0.2	0.1	-0.2	0.1	-0.2	-0.1	-0.4	-0.3	-0.4	-0.1	0.3
W	0	-0.8	-0.2	0	-0.5	-0.3	-0.7	-0.3	0	-0.2	0.1	0.9	0.1	0.4	0.1	0.7	-0.2	0.3	0.5	-0.3
Y	-0.2	-0.6	0	0.5	0	0.3	-0.3	-0.2	0.3	0.7	-0.2	-0.5	0	0.3	-0.5	0.6	-0.1	-0.3	0.3	0.2
D	-0.1	0.1	-0.2	0	0.2	-0.1	-0.1	-0.2	0	0	0	0	-0.1	0	0	-0.1	0.2	0	0	-0.1
E	-0.1	-0.3	-0.1	-0.1	0.1	0	-0.2	0	0	0	0	0	0	0	0	0	0	0	0	0
K	0.1	-0.3	-0.1	-0.1	0	-0.1	-0.2	0.1	0	0	0	0	-0.1	0	0	-0.1	-0.1	0.2	0	-0.1
R	0.6	-0.3	-0.3	-0.2	0.1	-0.1	-0.2	0.1	0	0	0	0.2	-0.1	0.2	0	-0.1	0.1	0	0	-0.1
H	0.5	-0.6	0.3	-0.2	-0.2	-0.1	-0.2	-0.2	0	0	0	0.2	-0.1	0	0.1	-0.1	-0.1	0	0	-0.1
N	-0.1	-0.2	-0.2	-0.2	0	-0.1	0.1	0.1	0	0	0	0	-0.1	0	0.2	-0.1	-0.1	0	0	-0.1
Q	-0.1	-0.4	0.4	-0.2	0	0.2	-0.2	-0.2	0	0	0	0	0	0	0	-0.1	0.2	0	0	-0.1
S	-0.5	0.5	0	-0.4	-0.4	0.2	0.5	0.7	0	-0.1	0	-0.1	0.2	-0.1	0	-0.4	0.2	-0.1	-0.1	-0.3
T	-0.4	0.2	-0.2	0.4	0.1	1.1	-0.2	-0.5	0	-0.1	0	-0.1	0	-0.1	-0.1	0.1	-0.2	0.3	-0.1	-0.1
G	-0.1	0.4	-0.2	0.3	0	-0.2	0.2	0.1	0	-0.1	0	-0.1	-0.1	0	0.1	-0.2	0	0	-0.1	0
P	-0.1	0.2	-0.2	0	0	-0.1	0	-0.2	0	0	0	0	0	0	0	-0.1	-0.1	0	0	-0.1
C	0.4	0.2	-0.8	-0.8	-0.5	-0.2	-0.5	0.6	-0.1	0.6	0.1	0.3	0.2	0	0.3	0	0.1	0.1	-0.4	0.3

Conservation matrix (aka PSSM)

-	A	F	I	L	V	M	W	Y	D	E	K	R	H	N	Q	S	T	G	P	C
0095	0.2	1.4	2	2.5	1.8	0.7	-0.2	0.6	-1.1	-1.4	-1.1	-0.6	-1.2	-1.1	-1	-0.1	-0.2	-0.3	-1	-0.1
0133	0.7	0.7	0.5	0.8	1.1	0.3	-0.3	0.5	-0.9	-0.8	-0.8	-0.3	-0.6	-0.4	-0.8	0.3	0.6	-0.6	0	0

Select residue pair below:

i_j	Score	Prob
0095_0105	1.054	0.95
0095_0140	1.026	0.94
0044_0095	0.729	0.65
0089_0095	0.670	0.56
0095_0133	0.642	0.51

Local Interactions:

i_j	Score	Prob
0095_0096	0.954	0.90
0094_0095	0.888	0.85

See all coupling residues
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