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ACCC - PUR5
UniProt: P24182 - P08178
Length: 794
Sequences: 477
Seq/Len: 0.66
I_Prob: 0.00

ACCC - Biotin carboxylase
Paralog alert: 0.87 [within 20: 0.13] - ratio of genomes with paralogs
Cluster includes: ACCC DDLA DDLB GSHB PUR2 PURK PURT RIMK
PUR5 - Phosphoribosylformylglycinamidine cyclo-ligase
Paralog alert: 0.02 [within 20: 0.01] - ratio of genomes with paralogs
Cluster includes: PUR5
GREMLIN Results (Scaled_score > 1):

Legend: The darker and larger the blue dots, the higher strength in coevolution.

Residue pairs sorted by strength in coevolution signal:
i j Scaled Score I_Prob
272_A 135_C 1.12 0.00
198_V 165_E 1.04 0.00
275_F 97_V 1.04 0.00
243_A 152_E 1.03 0.00
8_A 285_T 1.02 0.00
106_K 279_V 1.02 0.00
8_A 171_D 1.00 0.00
5_I 131_L 0.97 0.00
394_N 269_I 0.96 0.00
112_L 85_I 0.94 0.00
200_M 83_I 0.94 0.00
303_I 185_G 0.91 0.00
236_H 16_I 0.91 0.00
401_R 163_V 0.88 0.00
279_F 185_G 0.88 0.00
291_T 302_V 0.88 0.00
404_N 310_A 0.86 0.00
68_S 243_H 0.85 0.00
338_R 127_A 0.84 0.00
109_T 261_L 0.84 0.00
286_F 156_V 0.83 0.00
301_E 15_D 0.83 0.00
243_A 289_V 0.83 0.00
389_I 194_Y 0.82 0.00
256_I 97_V 0.82 0.00
107_A 227_R 0.82 0.00
5_I 39_M 0.81 0.00
300_T 227_R 0.81 0.00
71_E 42_L 0.81 0.00
334_A 44_G 0.80 0.00
287_I 8_S 0.80 0.00
192_A 312_E 0.80 0.00
341_A 55_Y 0.80 0.00
272_A 227_R 0.80 0.00
79_H 131_L 0.80 0.00
77_A 104_F 0.80 0.00
287_I 293_E 0.80 0.00
311_E 283_L 0.79 0.00
287_I 46_G 0.79 0.00
74_G 335_A 0.79 0.00
172_V 46_G 0.79 0.00
274_T 97_V 0.78 0.00
268_G 242_V 0.78 0.00
173_R 12_A 0.78 0.00
119_A 189_P 0.78 0.00
378_P 277_P 0.78 0.00
204_L 166_K 0.77 0.00
233_Q 101_E 0.77 0.00
376_T 26_I 0.77 0.00
214_V 330_I 0.77 0.00
239_V 114_L 0.77 0.00
233_Q 18_A 0.76 0.00
357_F 313_V 0.76 0.00
143_D 310_A 0.76 0.00
233_Q 44_G 0.76 0.00
125_K 194_Y 0.76 0.00
7_I 334_K 0.75 0.00
387_K 52_P 0.75 0.00
365_V 279_V 0.75 0.00
339_I 214_D 0.75 0.00
182_I 221_H 0.75 0.00
154_Y 87_L 0.74 0.00
222_A 261_L 0.74 0.00
212_I 42_L 0.74 0.00
128_V 46_G 0.74 0.00
316_A 194_Y 0.74 0.00
194_S 44_G 0.74 0.00
4_K 132_Q 0.74 0.00
127_G 182_I 0.74 0.00
8_A 330_I 0.73 0.00
322_S 242_V 0.73 0.00
241_E 48_L 0.73 0.00
374_G 177_D 0.73 0.00
347_F 73_L 0.73 0.00
8_A 276_W 0.73 0.00
269_Y 182_I 0.73 0.00
390_C 217_P 0.72 0.00
198_V 82_T 0.72 0.00
17_I 151_G 0.72 0.00
222_A 131_L 0.72 0.00
264_C 184_L 0.72 0.00
158_I 315_K 0.72 0.00
77_A 109_Y 0.72 0.00
397_V 319_L 0.72 0.00
269_Y 270_D 0.72 0.00
233_Q 35_R 0.72 0.00
107_A 173_S 0.71 0.00
242_E 98_Q 0.71 0.00
419_D 334_K 0.71 0.00
339_I 277_P 0.71 0.00
269_Y 20_N 0.71 0.00
5_I 316_A 0.71 0.00
338_R 136_S 0.71 0.00
262_K 257_I 0.71 0.00
63_I 133_S 0.70 0.00
143_D 318_A 0.70 0.00
335_V 261_L 0.70 0.00
247_G 50_A 0.70 0.00
245_A 296_R 0.70 0.00
252_L 185_G 0.70 0.00
373_A 12_A 0.70 0.00
371_I 261_L 0.69 0.00
106_K 276_W 0.69 0.00
8_A 173_S 0.69 0.00
416_T 320_L 0.69 0.00
268_G 199_K 0.69 0.00
282_G 83_I 0.69 0.00
86_S 295_Y 0.69 0.00
138_L 228_I 0.69 0.00
374_G 174_K 0.69 0.00
300_T 156_V 0.68 0.00
122_A 119_A 0.68 0.00
335_V 87_L 0.68 0.00
311_E 213_L 0.68 0.00
374_G 257_I 0.68 0.00
311_E 111_T 0.68 0.00
245_A 97_V 0.68 0.00
112_L 194_Y 0.68 0.00
171_V 10_K 0.68 0.00
278_L 55_Y 0.67 0.00
200_M 156_V 0.67 0.00
261_A 126_I 0.67 0.00
388_L 180_V 0.67 0.00
400_A 332_I 0.67 0.00
266_D 318_A 0.67 0.00
401_R 285_T 0.67 0.00
379_P 26_I 0.67 0.00
Legend: The i (protein A) and j (protein B) are positions as given in the UniProt sequences. The value of the raw score is the function of the learning procedure, L2 normalization and APC (entropic) correction.

Scaled Score = raw_score/average(raw_scores)
I_Prob = P(contact | scaled_score, seq/len, top_inter_score)

Text file of predictions
(includes both intra and inter preds)

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