| UniProt: | P77467 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13741 | ||
| Length: | 262 (258) | ||
| Sequences: | 13163 | ||
| Seq/Len: | 51.02 |
| PAAG
Paralog alert: 0.70 [within 20: 0.25] - ratio of genomes with paralogs Cluster includes: CAID MENB PAAF PAAG SCPB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 183_Q | 193_T | 3.254 | 1.00 | |
| 128_R | 186_D | 3.157 | 1.00 | |
| 131_K | 169_Q | 3.105 | 1.00 | |
| 193_T | 196_Q | 3.014 | 1.00 | |
| 126_A | 181_I | 2.954 | 1.00 | |
| 104_C | 121_G | 2.658 | 1.00 | |
| 15_T | 195_Q | 2.572 | 1.00 | |
| 43_E | 99_P | 2.526 | 1.00 | |
| 129_S | 187_D | 2.494 | 1.00 | |
| 168_N | 200_H | 2.435 | 1.00 | |
| 6_L | 19_N | 2.32 | 1.00 | |
| 171_S | 174_Q | 2.316 | 1.00 | |
| 162_G | 168_N | 2.205 | 1.00 | |
| 138_K | 204_Q | 2.184 | 1.00 | |
| 24_L | 58_R | 2.181 | 1.00 | |
| 223_T | 226_T | 2.161 | 1.00 | |
| 174_Q | 177_E | 2.161 | 1.00 | |
| 249_S | 253_A | 2.094 | 1.00 | |
| 40_K | 94_R | 2.079 | 1.00 | |
| 128_R | 173_E | 2.058 | 1.00 | |
| 159_R | 178_W | 2.036 | 1.00 | |
| 189_T | 192_D | 2.016 | 1.00 | |
| 105_A | 194_A | 2.014 | 1.00 | |
| 125_I | 185_V | 1.986 | 1.00 | |
| 111_A | 133_V | 1.919 | 1.00 | |
| 105_A | 191_A | 1.915 | 1.00 | |
| 24_L | 59_G | 1.835 | 1.00 | |
| 30_E | 34_Q | 1.815 | 1.00 | |
| 19_N | 56_A | 1.789 | 1.00 | |
| 174_Q | 178_W | 1.752 | 1.00 | |
| 14_M | 42_V | 1.746 | 1.00 | |
| 51_L | 98_L | 1.746 | 1.00 | |
| 173_E | 177_E | 1.743 | 1.00 | |
| 54_T | 107_N | 1.743 | 1.00 | |
| 15_T | 54_T | 1.735 | 1.00 | |
| 17_T | 56_A | 1.728 | 1.00 | |
| 12_G | 49_R | 1.721 | 1.00 | |
| 162_G | 182_W | 1.72 | 1.00 | |
| 242_A | 262_K | 1.714 | 1.00 | |
| 128_R | 187_D | 1.688 | 1.00 | |
| 168_N | 174_Q | 1.687 | 1.00 | |
| 9_V | 14_M | 1.68 | 1.00 | |
| 9_V | 45_D | 1.662 | 1.00 | |
| 246_E | 255_R | 1.652 | 1.00 | |
| 161_M | 216_I | 1.633 | 1.00 | |
| 164_A | 212_I | 1.631 | 1.00 | |
| 42_V | 51_L | 1.627 | 1.00 | |
| 162_G | 183_Q | 1.608 | 1.00 | |
| 125_I | 197_L | 1.607 | 1.00 | |
| 126_A | 132_F | 1.596 | 1.00 | |
| 161_M | 217_N | 1.591 | 1.00 | |
| 7_S | 14_M | 1.586 | 1.00 | |
| 17_T | 54_T | 1.573 | 1.00 | |
| 118_A | 124_V | 1.559 | 1.00 | |
| 161_M | 165_L | 1.546 | 1.00 | |
| 36_A | 94_R | 1.54 | 1.00 | |
| 157_R | 161_M | 1.54 | 1.00 | |
| 11_K | 199_R | 1.524 | 1.00 | |
| 195_Q | 199_R | 1.521 | 1.00 | |
| 41_Q | 45_D | 1.508 | 1.00 | |
| 189_T | 193_T | 1.499 | 1.00 | |
| 124_V | 158_A | 1.493 | 1.00 | |
| 124_V | 154_V | 1.468 | 1.00 | |
| 242_A | 260_T | 1.466 | 1.00 | |
| 185_V | 193_T | 1.462 | 1.00 | |
| 137_S | 167_G | 1.456 | 1.00 | |
| 14_M | 48_I | 1.448 | 1.00 | |
| 95_L | 102_V | 1.439 | 1.00 | |
| 10_E | 199_R | 1.433 | 1.00 | |
| 50_C | 198_A | 1.43 | 1.00 | |
| 18_L | 31_M | 1.43 | 1.00 | |
| 7_S | 42_V | 1.424 | 1.00 | |
| 176_H | 184_V | 1.418 | 1.00 | |
| 16_L | 38_C | 1.407 | 0.99 | |
| 127_A | 187_D | 1.401 | 0.99 | |
| 43_E | 94_R | 1.382 | 0.99 | |
| 122_D | 213_K | 1.377 | 0.99 | |
| 28_N | 31_M | 1.371 | 0.99 | |
| 106_V | 110_A | 1.365 | 0.99 | |
| 107_N | 127_A | 1.358 | 0.99 | |
| 163_L | 170_L | 1.355 | 0.99 | |
| 10_E | 195_Q | 1.349 | 0.99 | |
| 107_N | 129_S | 1.34 | 0.99 | |
| 39_L | 98_L | 1.334 | 0.99 | |
| 115_A | 134_M | 1.314 | 0.99 | |
| 159_R | 162_G | 1.306 | 0.99 | |
| 190_L | 194_A | 1.301 | 0.99 | |
| 29_D | 68_D | 1.301 | 0.99 | |
| 15_T | 191_A | 1.288 | 0.99 | |
| 52_L | 194_A | 1.276 | 0.99 | |
| 214_Q | 218_S | 1.262 | 0.99 | |
| 58_R | 107_N | 1.257 | 0.99 | |
| 191_A | 195_Q | 1.257 | 0.99 | |
| 127_A | 190_L | 1.256 | 0.99 | |
| 191_A | 194_A | 1.245 | 0.98 | |
| 36_A | 40_K | 1.217 | 0.98 | |
| 51_L | 100_K | 1.204 | 0.98 | |
| 23_R | 67_N | 1.203 | 0.98 | |
| 96_A | 150_L | 1.194 | 0.98 | |
| 106_V | 118_A | 1.189 | 0.98 | |
| 133_V | 169_Q | 1.186 | 0.98 | |
| 198_A | 202_A | 1.181 | 0.98 | |
| 156_G | 159_R | 1.179 | 0.98 | |
| 159_R | 174_Q | 1.179 | 0.98 | |
| 34_Q | 38_C | 1.177 | 0.98 | |
| 54_T | 191_A | 1.175 | 0.98 | |
| 172_A | 184_V | 1.173 | 0.98 | |
| 20_R | 23_R | 1.153 | 0.97 | |
| 158_A | 182_W | 1.147 | 0.97 | |
| 33_A | 87_F | 1.133 | 0.97 | |
| 222_N | 226_T | 1.131 | 0.97 | |
| 123_I | 197_L | 1.11 | 0.96 | |
| 93_R | 97_K | 1.102 | 0.96 | |
| 148_T | 231_E | 1.099 | 0.96 | |
| 10_E | 15_T | 1.092 | 0.96 | |
| 18_L | 61_C | 1.092 | 0.96 | |
| 151_L | 155_A | 1.082 | 0.96 | |
| 109_V | 131_K | 1.081 | 0.95 | |
| 170_L | 178_W | 1.079 | 0.95 | |
| 155_A | 159_R | 1.078 | 0.95 | |
| 20_R | 65_D | 1.073 | 0.95 | |
| 67_N | 252_L | 1.071 | 0.95 | |
| 106_V | 132_F | 1.056 | 0.95 | |
| 6_L | 56_A | 1.052 | 0.95 | |
| 61_C | 114_G | 1.051 | 0.94 | |
| 93_R | 225_D | 1.05 | 0.94 | |
| 15_T | 52_L | 1.042 | 0.94 | |
| 204_Q | 209_L | 1.041 | 0.94 | |
| 37_E | 41_Q | 1.035 | 0.94 | |
| 201_L | 209_L | 1.033 | 0.94 | |
| 46_D | 100_K | 1.031 | 0.94 | |
| 244_Y | 248_V | 1.026 | 0.94 | |
| 186_D | 189_T | 1.026 | 0.94 | |
| 43_E | 98_L | 1.015 | 0.93 | |
| 194_A | 198_A | 1.014 | 0.93 | |
| 173_E | 176_H | 1.014 | 0.93 | |
| 8_H | 17_T | 1.004 | 0.93 | |
| 123_I | 182_W | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4fzwC | 2 | 1 | 100 | 0.055 | Contact Map | 0.663 |
| 3g64A | 3 | 1 | 100 | 0.057 | Contact Map | 0.692 |
| 4mi2A | 3 | 1 | 100 | 0.06 | Contact Map | 0.724 |
| 4lk5A | 3 | 0.9924 | 100 | 0.061 | Contact Map | 0.712 |
| 4jfcA | 1 | 0.9885 | 100 | 0.062 | Contact Map | 0.7 |
| 3qxzA | 3 | 0.9809 | 100 | 0.064 | Contact Map | 0.742 |
| 3sllA | 6 | 1 | 100 | 0.064 | Contact Map | 0.854 |
| 2ej5A | 2 | 0.9809 | 100 | 0.065 | Contact Map | 0.703 |
| 3peaA | 6 | 0.9847 | 100 | 0.065 | Contact Map | 0.767 |
| 4jwvA | 2 | 0.9771 | 100 | 0.066 | Contact Map | 0.662 |
Sequence Conservation (Image Generated using WebLogo v3)