| UniProt: | P76082 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13740 | ||
| Length: | 255 (252) | ||
| Sequences: | 13444 | ||
| Seq/Len: | 53.35 |
| PAAF
Paralog alert: 0.70 [within 20: 0.25] - ratio of genomes with paralogs Cluster includes: CAID MENB PAAF PAAG SCPB |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 176_D | 186_Y | 3.167 | 1.00 | |
| 124_R | 162_S | 3.081 | 1.00 | |
| 121_E | 179_P | 3.043 | 1.00 | |
| 186_Y | 189_Q | 2.899 | 1.00 | |
| 119_A | 174_V | 2.869 | 1.00 | |
| 97_A | 114_C | 2.601 | 1.00 | |
| 42_A | 92_N | 2.541 | 1.00 | |
| 14_L | 188_L | 2.53 | 1.00 | |
| 122_N | 180_S | 2.493 | 1.00 | |
| 161_E | 193_K | 2.339 | 1.00 | |
| 164_T | 167_Q | 2.318 | 1.00 | |
| 5_I | 18_N | 2.31 | 1.00 | |
| 155_K | 161_E | 2.199 | 1.00 | |
| 131_T | 197_H | 2.165 | 1.00 | |
| 167_Q | 170_Q | 2.159 | 1.00 | |
| 23_R | 57_R | 2.148 | 1.00 | |
| 216_A | 219_A | 2.141 | 1.00 | |
| 39_E | 87_R | 2.11 | 1.00 | |
| 152_L | 171_A | 2.045 | 1.00 | |
| 242_S | 246_Q | 1.997 | 1.00 | |
| 98_A | 187_A | 1.971 | 1.00 | |
| 104_L | 126_G | 1.946 | 1.00 | |
| 157_V | 205_A | 1.936 | 1.00 | |
| 121_E | 166_Q | 1.928 | 1.00 | |
| 118_V | 178_F | 1.924 | 1.00 | |
| 182_L | 185_E | 1.86 | 1.00 | |
| 23_R | 58_F | 1.857 | 1.00 | |
| 98_A | 184_L | 1.856 | 1.00 | |
| 18_N | 55_N | 1.807 | 1.00 | |
| 29_A | 33_Q | 1.804 | 1.00 | |
| 13_L | 41_A | 1.759 | 1.00 | |
| 50_C | 91_F | 1.755 | 1.00 | |
| 11_R | 48_S | 1.752 | 1.00 | |
| 14_L | 53_T | 1.751 | 1.00 | |
| 239_E | 248_R | 1.75 | 1.00 | |
| 155_K | 175_S | 1.731 | 1.00 | |
| 167_Q | 171_A | 1.721 | 1.00 | |
| 235_E | 255_R | 1.72 | 1.00 | |
| 16_T | 55_N | 1.71 | 1.00 | |
| 8_R | 13_L | 1.687 | 1.00 | |
| 53_T | 100_N | 1.68 | 1.00 | |
| 166_Q | 170_Q | 1.67 | 1.00 | |
| 121_E | 180_S | 1.636 | 1.00 | |
| 41_A | 50_C | 1.606 | 1.00 | |
| 119_A | 125_F | 1.606 | 1.00 | |
| 161_E | 167_Q | 1.601 | 1.00 | |
| 154_S | 209_L | 1.594 | 1.00 | |
| 8_R | 44_D | 1.589 | 1.00 | |
| 16_T | 53_T | 1.589 | 1.00 | |
| 154_S | 210_R | 1.586 | 1.00 | |
| 155_K | 176_D | 1.582 | 1.00 | |
| 6_V | 13_L | 1.576 | 1.00 | |
| 150_K | 154_S | 1.561 | 1.00 | |
| 111_A | 117_V | 1.556 | 1.00 | |
| 118_V | 190_L | 1.54 | 1.00 | |
| 35_V | 87_R | 1.54 | 1.00 | |
| 115_D | 206_K | 1.531 | 1.00 | |
| 154_S | 158_L | 1.509 | 1.00 | |
| 188_L | 192_S | 1.492 | 1.00 | |
| 130_I | 160_G | 1.492 | 1.00 | |
| 117_V | 151_S | 1.485 | 1.00 | |
| 40_A | 44_D | 1.478 | 1.00 | |
| 10_Q | 192_S | 1.47 | 1.00 | |
| 42_A | 87_R | 1.46 | 1.00 | |
| 182_L | 186_Y | 1.451 | 1.00 | |
| 235_E | 253_K | 1.438 | 1.00 | |
| 178_F | 186_Y | 1.437 | 1.00 | |
| 117_V | 147_S | 1.434 | 1.00 | |
| 88_L | 95_L | 1.427 | 1.00 | |
| 13_L | 47_I | 1.417 | 1.00 | |
| 17_L | 30_L | 1.404 | 0.99 | |
| 49_V | 191_A | 1.385 | 0.99 | |
| 15_L | 37_E | 1.367 | 0.99 | |
| 27_N | 30_L | 1.365 | 0.99 | |
| 156_M | 163_I | 1.362 | 0.99 | |
| 169_Q | 177_V | 1.352 | 0.99 | |
| 9_Q | 192_S | 1.35 | 0.99 | |
| 6_V | 41_A | 1.345 | 0.99 | |
| 99_V | 103_A | 1.343 | 0.99 | |
| 207_Q | 211_Q | 1.342 | 0.99 | |
| 100_N | 120_G | 1.336 | 0.99 | |
| 120_G | 180_S | 1.335 | 0.99 | |
| 100_N | 122_N | 1.322 | 0.99 | |
| 108_C | 127_L | 1.321 | 0.99 | |
| 38_L | 91_F | 1.32 | 0.99 | |
| 183_T | 187_A | 1.265 | 0.99 | |
| 9_Q | 188_L | 1.26 | 0.99 | |
| 28_N | 67_E | 1.26 | 0.99 | |
| 120_G | 183_T | 1.244 | 0.98 | |
| 22_A | 66_N | 1.24 | 0.98 | |
| 89_Q | 143_R | 1.232 | 0.98 | |
| 14_L | 184_L | 1.229 | 0.98 | |
| 184_L | 188_L | 1.226 | 0.98 | |
| 152_L | 155_K | 1.222 | 0.98 | |
| 184_L | 187_A | 1.211 | 0.98 | |
| 35_V | 39_E | 1.208 | 0.98 | |
| 57_R | 100_N | 1.207 | 0.98 | |
| 33_Q | 37_E | 1.206 | 0.98 | |
| 51_V | 187_A | 1.199 | 0.98 | |
| 126_G | 162_S | 1.199 | 0.98 | |
| 50_C | 93_K | 1.198 | 0.98 | |
| 152_L | 167_Q | 1.152 | 0.97 | |
| 151_S | 175_S | 1.135 | 0.97 | |
| 19_R | 22_A | 1.132 | 0.97 | |
| 53_T | 184_L | 1.131 | 0.97 | |
| 99_V | 111_A | 1.13 | 0.97 | |
| 17_L | 60_A | 1.112 | 0.96 | |
| 165_A | 177_V | 1.109 | 0.96 | |
| 102_Y | 124_R | 1.103 | 0.96 | |
| 149_G | 152_L | 1.098 | 0.96 | |
| 86_A | 90_A | 1.094 | 0.96 | |
| 191_A | 195_A | 1.092 | 0.96 | |
| 204_A | 230_L | 1.085 | 0.96 | |
| 60_A | 107_G | 1.084 | 0.96 | |
| 215_V | 219_A | 1.076 | 0.95 | |
| 19_R | 64_D | 1.075 | 0.95 | |
| 141_T | 224_E | 1.074 | 0.95 | |
| 9_Q | 14_L | 1.07 | 0.95 | |
| 197_H | 202_L | 1.07 | 0.95 | |
| 116_V | 190_L | 1.058 | 0.95 | |
| 194_M | 202_L | 1.048 | 0.94 | |
| 66_N | 245_L | 1.042 | 0.94 | |
| 163_I | 171_A | 1.037 | 0.94 | |
| 86_A | 218_Q | 1.035 | 0.94 | |
| 219_A | 222_A | 1.032 | 0.94 | |
| 237_R | 241_I | 1.031 | 0.94 | |
| 148_V | 152_L | 1.029 | 0.94 | |
| 99_V | 117_V | 1.022 | 0.93 | |
| 144_L | 148_V | 1.022 | 0.93 | |
| 36_N | 40_A | 1.013 | 0.93 | |
| 7_S | 16_T | 1.004 | 0.93 | |
| 99_V | 125_F | 1.002 | 0.92 | |
| 45_T | 93_K | 1.002 | 0.92 | |
| 12_V | 49_V | 1.002 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4jwvA | 2 | 1 | 100 | 0.014 | Contact Map | 0.663 |
| 4lk5A | 3 | 1 | 100 | 0.017 | Contact Map | 0.71 |
| 4jfcA | 1 | 0.9922 | 100 | 0.021 | Contact Map | 0.703 |
| 4fzwC | 2 | 1 | 100 | 0.021 | Contact Map | 0.669 |
| 3sllA | 6 | 1 | 100 | 0.021 | Contact Map | 0.862 |
| 3kqfA | 6 | 1 | 100 | 0.021 | Contact Map | 0.826 |
| 3tlfA | 6 | 0.9961 | 100 | 0.022 | Contact Map | 0.798 |
| 1nzyA | 2 | 1 | 100 | 0.022 | Contact Map | 0.737 |
| 3qxzA | 3 | 0.9961 | 100 | 0.022 | Contact Map | 0.748 |
| 4fzwA | 2 | 1 | 100 | 0.022 | Contact Map | 0.686 |
Sequence Conservation (Image Generated using WebLogo v3)